Detalhe da pesquisa
1.
Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy.
Proc Natl Acad Sci U S A
; 111(11): 4019-24, 2014 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24550462
2.
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth.
Proc Natl Acad Sci U S A
; 111(11): 4025-30, 2014 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24550463
3.
OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation.
Proc Natl Acad Sci U S A
; 111(11): 4031-6, 2014 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24550447
4.
Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans.
Nat Chem Biol
; 8(12): 960-962, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23103944
5.
Dual-action inhibitors of HIF prolyl hydroxylases that induce binding of a second iron ion.
Org Biomol Chem
; 11(5): 732-745, 2013 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23151668
6.
5-Substituted Pyridine-2,4-dicarboxylate Derivatives Have Potential for Selective Inhibition of Human Jumonji-C Domain-Containing Protein 5.
J Med Chem
; 66(15): 10849-10865, 2023 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37527664
7.
Development and application of a fluoride-detection-based fluorescence assay for γ-butyrobetaine hydroxylase.
Chembiochem
; 13(11): 1559-63, 2012 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-22730246
8.
Improved synthesis of 5-hydroxymethyl-2'-deoxycytidine phosphoramidite using a 2'-deoxyuridine to 2'-deoxycytidine conversion without temporary protecting groups.
Bioorg Med Chem Lett
; 21(4): 1181-4, 2011 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21256007
9.
Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates.
Org Biomol Chem
; 9(1): 127-35, 2011 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21076780
10.
Synthesis of Novel Pyridine-Carboxylates as Small-Molecule Inhibitors of Human Aspartate/Asparagine-ß-Hydroxylase.
ChemMedChem
; 15(13): 1139-1149, 2020 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32330361
11.
Structure of the ribosomal oxygenase OGFOD1 provides insights into the regio- and stereoselectivity of prolyl hydroxylases.
Structure
; 23(4): 639-52, 2015 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25728928
12.
Structural insights into how 5-hydroxymethylation influences transcription factor binding.
Chem Commun (Camb)
; 50(15): 1794-6, 2014 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24287551
13.
Fluoromethylated derivatives of carnitine biosynthesis intermediates--synthesis and applications.
Chem Commun (Camb)
; 50(10): 1175-7, 2014 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24317009
14.
Role of the jelly-roll fold in substrate binding by 2-oxoglutarate oxygenases.
Curr Opin Struct Biol
; 22(6): 691-700, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23142576
15.
Hydroxylation of methylated CpG dinucleotides reverses stabilisation of DNA duplexes by cytosine 5-methylation.
Chem Commun (Camb)
; 47(18): 5325-7, 2011 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21451870
16.
Stereoselective C-C bond formation catalysed by engineered carboxymethylproline synthases.
Nat Chem
; 3(5): 365-71, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21505494
17.
Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α).
PLoS One
; 6(1): e16210, 2011 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21264265
18.
Photoactivable peptides for identifying enzyme-substrate and protein-protein interactions.
Chem Commun (Camb)
; 47(5): 1488-90, 2011 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21152646
19.
Inhibition of the histone lysine demethylase JMJD2A by ejection of structural Zn(II).
Chem Commun (Camb)
; (42): 6376-8, 2009 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-19841782
20.
Quantitative modeling of triacylglycerol homeostasis in yeast--metabolic requirement for lipolysis to promote membrane lipid synthesis and cellular growth.
FEBS J
; 275(22): 5552-63, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18959743