Detalhe da pesquisa
1.
First-in-human study of IM156, a novel potent biguanide oxidative phosphorylation (OXPHOS) inhibitor, in patients with advanced solid tumors.
Invest New Drugs
; 40(5): 1001-1010, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35802288
2.
First-in-Human Evaluation of the Safety, Tolerability, and Pharmacokinetics of SPR720, a Novel Oral Bacterial DNA Gyrase (GyrB) Inhibitor for Mycobacterial Infections.
Antimicrob Agents Chemother
; 65(11): e0120821, 2021 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34491803
3.
Roflumilast Cream Improves Signs and Symptoms of Plaque Psoriasis: Results from a Phase 1/2a Randomized, Controlled Study.
J Drugs Dermatol
; 19(8): 734-740, 2020 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32845114
4.
Pharmacokinetics of Roflumilast Cream in Chronic Plaque Psoriasis: Data from Phase I to Phase III Studies.
Am J Clin Dermatol
; 24(2): 315-324, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36422852
5.
Zilovertamab Vedotin Targeting of ROR1 as Therapy for Lymphoid Cancers.
NEJM Evid
; 1(1): EVIDoa2100001, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38319241
6.
Clinical stage molecule PT150 is a modulator of glucocorticoid and androgen receptors with antiviral activity against SARS-CoV-2.
Cell Cycle
; 19(24): 3632-3638, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33305659
7.
Identification of interspecies difference in efflux transporters of hepatocytes from dog, rat, monkey and human.
Eur J Pharm Sci
; 35(1-2): 114-26, 2008 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-18639632
8.
Pharmacokinetic and pharmacodynamic evaluation of the suitability of using fluticasone and an acute rat lung inflammation model to differentiate lung versus systemic efficacy.
J Pharm Sci
; 98(11): 4354-64, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19230021
9.
Fluticasone and budesonide nanosuspensions for pulmonary delivery: preparation, characterization, and pharmacokinetic studies.
J Pharm Sci
; 97(11): 4869-78, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18351635
10.
Development of an in vitro drug-drug interaction assay to simultaneously monitor five cytochrome P450 isoforms and performance assessment using drug library compounds.
J Pharmacol Toxicol Methods
; 58(3): 206-14, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18634893