Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Whole-genome and transcriptome analysis enhances precision cancer treatment options.

Pleasance, E; Bohm, A; Williamson, L M; Nelson, J M T; Shen, Y; Bonakdar, M; Titmuss, E; Csizmok, V; Wee, K; Hosseinzadeh, S; Grisdale, C J; Reisle, C; Taylor, G A; Lewis, E; Jones, M R; Bleile, D; Sadeghi, S; Zhang, W; Davies, A; Pellegrini, B; Wong, T; Bowlby, R; Chan, S K; Mungall, K L; Chuah, E; Mungall, A J; Moore, R A; Zhao, Y; Deol, B; Fisic, A; Fok, A; Regier, D A; Weymann, D; Schaeffer, D F; Young, S; Yip, S; Schrader, K; Levasseur, N; Taylor, S K; Feng, X; Tinker, A; Savage, K J; Chia, S; Gelmon, K; Sun, S; Lim, H; Renouf, D J; Jones, S J M; Marra, M A; Laskin, J.

Ann Oncol ; 33(9): 939-949, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-35691590

2.

Early inflammation precedes cardiac fibrosis and heart failure in desmoglein 2 murine model of arrhythmogenic cardiomyopathy.

Ng, K E; Delaney, P J; Thenet, D; Murtough, S; Webb, C M; Zaman, N; Tsisanova, E; Mastroianni, G; Walker, S L M; Westaby, J D; Pennington, D J; Pink, R; Kelsell, D P; Tinker, A.

Cell Tissue Res ; 386(1): 79-98, 2021 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-34236518

3.

A Canadian cancer trials group phase IB study of durvalumab (anti-PD-L1) plus tremelimumab (anti-CTLA-4) given concurrently or sequentially in patients with advanced, incurable solid malignancies.

Nehra, J; Bradbury, P A; Ellis, P M; Laskin, J; Kollmannsberger, C; Hao, D; Juergens, R A; Goss, G; Wheatley-Price, P; Hotte, S J; Gelmon, K; Tinker, A V; Brown-Walker, P; Gauthier, I; Tu, D; Song, X; Khan, A; Seymour, Lesley; Smoragiewicz, M.

Invest New Drugs ; 38(5): 1442-1447, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-32020438

4.

Loss-of-function desmoplakin I and II mutations underlie dominant arrhythmogenic cardiomyopathy with a hair and skin phenotype.

Maruthappu, T; Posafalvi, A; Castelletti, S; Delaney, P J; Syrris, P; O'Toole, E A; Green, K J; Elliott, P M; Lambiase, P D; Tinker, A; McKenna, W J; Kelsell, D P.

Br J Dermatol ; 180(5): 1114-1122, 2019 05.

Artigo em Inglês | MEDLINE | ID: mdl-30382575

5.

Phase II study of temsirolimus (CCI-779) in women with recurrent, unresectable, locally advanced or metastatic carcinoma of the cervix. A trial of the NCIC Clinical Trials Group (NCIC CTG IND 199).

Tinker, A V; Ellard, S; Welch, S; Moens, F; Allo, G; Tsao, M S; Squire, J; Tu, D; Eisenhauer, E A; MacKay, H.

Gynecol Oncol ; 130(2): 269-74, 2013 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-23672928

6.

Hyperinsulinaemic hypoglycaemia and diabetes mellitus due to dominant ABCC8/KCNJ11 mutations.

Kapoor, R R; Flanagan, S E; James, C T; McKiernan, J; Thomas, A M; Harmer, S C; Shield, J P; Tinker, A; Ellard, S; Hussain, K.

Diabetologia ; 54(10): 2575-83, 2011 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-21674179

7.

Exploring palliative treatment outcomes in women with advanced or recurrent ovarian clear cell carcinoma.

Al-Barrak, J; Santos, J L; Tinker, A; Hoskins, P; Gilks, C B; Lau, H; Swenerton, K D.

Gynecol Oncol ; 122(1): 107-10, 2011 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-21463887

8.

18F FDG positron-emission tomography findings of gliomatosis peritonei: A case report and review of the literature.

Lavoie, J-M; Lacroix-Poisson, F; Hoang, L N; Wilson, D C; Seckl, M J; Tinker, A V.

Gynecol Oncol Rep ; 20: 105-107, 2017 May.

Artigo em Inglês | MEDLINE | ID: mdl-28393096

9.

The right to a healthy newborn.

Tinker, A G; Paul, V K; Ruben, J D.

Int J Gynaecol Obstet ; 94(3): 269-76, 2006 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-16839556

10.

Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistance.

He, Y; Wu, A C; Harrington, B S; Davies, C M; Wallace, S J; Adams, M N; Palmer, J S; Roche, D K; Hollier, B G; Westbrook, T F; Hamidi, H; Konecny, G E; Winterhoff, B; Chetty, N P; Crandon, A J; Oliveira, N B; Shannon, C M; Tinker, A V; Gilks, C B; Coward, J I; Lumley, J W; Perrin, L C; Armes, J E; Hooper, J D.

Oncogene ; 35(4): 468-78, 2016 Jan 28.

Artigo em Inglês | MEDLINE | ID: mdl-25893298

11.

K(ATP) channel gene expression is induced by urocortin and mediates its cardioprotective effect.

Lawrence, K M; Chanalaris, A; Scarabelli, T; Hubank, M; Pasini, E; Townsend, P A; Comini, L; Ferrari, R; Tinker, A; Stephanou, A; Knight, R A; Latchman, D S.

Circulation ; 106(12): 1556-62, 2002 Sep 17.

Artigo em Inglês | MEDLINE | ID: mdl-12234964

12.

Probing the structure of the conduction pathway of the sheep cardiac sarcoplasmic reticulum calcium-release channel with permeant and impermeant organic cations.

Tinker, A; Williams, A J.

J Gen Physiol ; 102(6): 1107-29, 1993 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-8133241

13.

Divalent cation conduction in the ryanodine receptor channel of sheep cardiac muscle sarcoplasmic reticulum.

Tinker, A; Williams, A J.

J Gen Physiol ; 100(3): 479-93, 1992 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-1279095

14.

How does ryanodine modify ion handling in the sheep cardiac sarcoplasmic reticulum Ca(2+)-release channel?

Lindsay, A R; Tinker, A; Williams, A J.

J Gen Physiol ; 104(3): 425-47, 1994 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-7807056

15.

A model for ionic conduction in the ryanodine receptor channel of sheep cardiac muscle sarcoplasmic reticulum.

Tinker, A; Lindsay, A R; Williams, A J.

J Gen Physiol ; 100(3): 495-517, 1992 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-1279096

16.

Cation conduction in the calcium release channel of the cardiac sarcoplasmic reticulum under physiological and pathophysiological conditions.

Tinker, A; Lindsay, A R; Williams, A J.

Cardiovasc Res ; 27(10): 1820-5, 1993 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-8275529

17.

A spectrum of functional effects for disease causing mutations in the Jervell and Lange-Nielsen syndrome.

Huang, L; Bitner-Glindzicz, M; Tranebjaerg, L; Tinker, A.

Cardiovasc Res ; 51(4): 670-80, 2001 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-11530100

18.

Dose-dense paclitaxel in advanced ovarian cancer.

Kumar, A; Hoskins, P J; Tinker, A V.

Clin Oncol (R Coll Radiol) ; 27(1): 40-7, 2015 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-25455846

19.

Detection of interleukin-1 and interleukin-6 in adult rat brain, following mechanical injury, by in vivo microdialysis: evidence of a role for microglia in cytokine production.

Woodroofe, M N; Sarna, G S; Wadhwa, M; Hayes, G M; Loughlin, A J; Tinker, A; Cuzner, M L.

J Neuroimmunol ; 33(3): 227-36, 1991 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-1874973

20.

Women's health.

Curlin, P; Tinker, A.

Infect Dis Clin North Am ; 9(2): 335-51, 1995 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-7673671

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