Detalhe da pesquisa
1.
A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep.
Nat Genet
; 38(7): 813-8, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16751773
2.
Mice deleted for GPAT3 have reduced GPAT activity in white adipose tissue and altered energy and cholesterol homeostasis in diet-induced obesity.
Am J Physiol Endocrinol Metab
; 306(10): E1176-87, 2014 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24714397
3.
Predictors of readmission to a psychiatry inpatient unit.
Compr Psychiatry
; 55(3): 426-30, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24405773
4.
Targeting Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) with small molecule inhibitors for the treatment of metabolic diseases.
J Biol Chem
; 286(48): 41838-41851, 2011 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-21990351
5.
Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent.
Proc Natl Acad Sci U S A
; 106(1): 262-7, 2009 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-19116277
6.
GPAT3 and GPAT4 are regulated by insulin-stimulated phosphorylation and play distinct roles in adipogenesis.
J Lipid Res
; 51(7): 1971-81, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20181984
7.
H6PDH interacts directly with 11beta-HSD1: implications for determining the directionality of glucocorticoid catalysis.
Arch Biochem Biophys
; 483(1): 45-54, 2009 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19121282
8.
Normal food intake and body weight in mice lacking the G protein-coupled receptor GPR39.
Endocrinology
; 148(2): 501-6, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17095592
9.
Structure-based optimization of protein tyrosine phosphatase 1B inhibitors: from the active site to the second phosphotyrosine binding site.
J Med Chem
; 50(19): 4681-98, 2007 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-17705360
10.
Nuclear receptors as drug targets in metabolic diseases: new approaches to therapy.
Trends Endocrinol Metab
; 17(7): 284-90, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16870465
11.
Bone morphogenetic proteins and growth differentiation factors as drug targets in cardiovascular and metabolic disease.
Drug Discov Today
; 11(9-10): 405-11, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16635802
12.
Molecular activation of PPARgamma by angiotensin II type 1-receptor antagonists.
Vascul Pharmacol
; 45(3): 154-62, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16765099
13.
Myostatin, a negative regulator of muscle mass: implications for muscle degenerative diseases.
Curr Opin Pharmacol
; 5(3): 328-32, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15907921
14.
Recent advances in the development of small molecule inhibitors of PTP1B for the treatment of insulin resistance and type 2 diabetes.
Curr Opin Drug Discov Devel
; 5(4): 500-12, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12197308
15.
Antibodies to B7.1 define the GFCC'C" face of the N-terminal domain as critical for co-stimulatory interactions.
Immunol Lett
; 83(2): 77-83, 2002 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-12067755
16.
Discovery of HSD-621 as a Potential Agent for the Treatment of Type 2 Diabetes.
ACS Med Chem Lett
; 4(1): 118-23, 2013 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900572
17.
Myostatin mutation associated with gross muscle hypertrophy in a child.
N Engl J Med
; 350(26): 2682-8, 2004 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-15215484
18.
A zymogen-like factor Xa variant corrects the coagulation defect in hemophilia.
Nat Biotechnol
; 29(11): 1028-33, 2011 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-22020385
19.
Bidirectional modulation of adipogenesis by the secreted protein Ccdc80/DRO1/URB.
J Biol Chem
; 284(12): 8136-47, 2009 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-19141617
20.
Efficacious 11beta-hydroxysteroid dehydrogenase type I inhibitors in the diet-induced obesity mouse model.
J Med Chem
; 52(17): 5449-61, 2009 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19673466