RESUMO
Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue tumor arising in the dermis. It is notorious for high rates of local recurrence despite its low metastatic potential. Although the etiology is unknown, DFSP often is considered to arise within scars and at sites of prior vaccination or trauma. Clinically, DFSP can be highly variable and mimic other soft tissue proliferations. We present a case of recurrent DFSP arising at the site of a Rho(D) immune globulin (Rhlg) injection that was administered 7 years prior. We also discuss the diagnostic challenges of DFSP as well as the indolent and locally recurrent nature of the tumor. This case serves to remind dermatologists of the highly variable clinical appearance of DFSP as well as to warn against presumptive diagnoses of lesions that mimic keloids and hypertrophic scars.
Assuntos
Cicatriz/complicações , Dermatofibrossarcoma/etiologia , Recidiva Local de Neoplasia/patologia , Imunoglobulina rho(D)/efeitos adversos , Neoplasias Cutâneas/etiologia , Adulto , Nádegas , Dermatofibrossarcoma/patologia , Dermatofibrossarcoma/cirurgia , Feminino , Humanos , Injeções Subcutâneas , Imunoglobulina rho(D)/administração & dosagem , Neoplasias Cutâneas/patologia , Neoplasias Cutâneas/cirurgiaRESUMO
Sweet syndrome, or acute febrile neutrophilic dermatosis, is characterized by the presence of fever, peripheral leukocytosis, painful erythematous plaques and nodules, and a predominately neutrophilic dermal infiltrate. We report a case occurring in a 10-week-old male child, with preceding upper respiratory tract, and gastrointestinal infection symptoms. Sweet syndrome occurring in an infant should prompt a work-up for immunodeficiency, as well as a review of the peripheral blood smear to rule out the rare case of malignancy.