Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Mezigdomide plus Dexamethasone in Relapsed and Refractory Multiple Myeloma.

Richardson, Paul G; Trudel, Suzanne; Popat, Rakesh; Mateos, María-Victoria; Vangsted, Annette J; Ramasamy, Karthik; Martinez-Lopez, Joaquín; Quach, Hang; Orlowski, Robert Z; Arnao, Mario; Lonial, Sagar; Karanes, Chatchada; Pawlyn, Charlotte; Kim, Kihyun; Oriol, Albert; Berdeja, Jesus G; Rodríguez Otero, Paula; Casas-Avilés, Ignacio; Spirli, Alessia; Poon, Jennifer; Li, Shaoyi; Gong, Jing; Wong, Lilly; Lamba, Manisha; Pierce, Daniel W; Amatangelo, Michael; Peluso, Teresa; Maciag, Paulo; Katz, Jessica; Pourdehnad, Michael; Bahlis, Nizar J.

N Engl J Med ; 389(11): 1009-1022, 2023 Sep 14.

Artigo em Inglês | MEDLINE | ID: mdl-37646702

2.

Safety and efficacy of belantamab mafodotin with pembrolizumab in patients with relapsed or refractory multiple myeloma.

Suvannasankha, Attaya; Bahlis, Nizar; Trudel, Suzanne; Weisel, Katja; Koenecke, Christian; Oriol, Albert; Voorhees, Peter M; Alonso, Aranzazu A; Callander, Natalie S; Mateos, María-Victoria; Reddy, Nishitha; Hakim, Shawn; LaMacchia, John; Patel, Nashita; Williams, Danaé; Jewell, Roxanne C; Zhou, Xiangdong; Gupta, Ira; Opalinska, Joanna; Nooka, Ajay K.

Cancer ; 2024 Apr 17.

Artigo em Inglês | MEDLINE | ID: mdl-38630908

3.

Single-agent belantamab mafodotin in patients with relapsed/refractory multiple myeloma: Final analysis of the DREAMM-2 trial.

Nooka, Ajay K; Cohen, Adam D; Lee, Hans C; Badros, Ashraf; Suvannasankha, Attaya; Callander, Natalie; Abdallah, Al-Ola; Trudel, Suzanne; Chari, Ajai; Libby, Edward N; Chaudhry, Maria; Hultcrantz, Malin; Kortüm, K Martin; Popat, Rakesh; Sborov, Douglas; Hakim, Shawn; Lewis, Eric; Gorsh, Boris; Bhushan, Bharat; McKeown, Astrid; Gupta, Ira; Opalinska, Joanna; Richardson, Paul G; Lonial, Sagar.

Cancer ; 129(23): 3746-3760, 2023 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-37622738

4.

Kinetics of response to first- and second-line therapies in multiple myeloma: Assessment by both M-spikes and light chains.

Lebel, Eyal; Li, Xuan; Paul, Harminder; Masih-Khan, Esther; Bhella, Sita; Chen, Christine; Prica, Anca; Reece, Donna; Tiedemann, Rodger; Trudel, Suzanne; Kukreti, Vishal.

Eur J Haematol ; 108(3): 204-211, 2022 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-34767270

5.

Longer term outcomes with single-agent belantamab mafodotin in patients with relapsed or refractory multiple myeloma: 13-month follow-up from the pivotal DREAMM-2 study.

Lonial, Sagar; Lee, Hans C; Badros, Ashraf; Trudel, Suzanne; Nooka, Ajay K; Chari, Ajai; Abdallah, Al-Ola; Callander, Natalie; Sborov, Douglas; Suvannasankha, Attaya; Weisel, Katja; Voorhees, Peter M; Womersley, Lynsey; Baron, January; Piontek, Trisha; Lewis, Eric; Opalinska, Joanna; Gupta, Ira; Cohen, Adam D.

Cancer ; 127(22): 4198-4212, 2021 11 15.

Artigo em Inglês | MEDLINE | ID: mdl-34314018

6.

Belantamab mafodotin in combination with novel agents in relapsed/refractory multiple myeloma: DREAMM-5 study design.

Nooka, Ajay K; Weisel, Katja; van de Donk, Niels Wcj; Routledge, David; Otero, Paula Rodriguez; Song, Kevin; Quach, Hang; Callander, Natalie; Minnema, Monique C; Trudel, Suzanne; Jackson, Nicola A; Ahlers, Christoph M; Im, Ellie; Cheng, Shinta; Smith, L; Hareth, Nahi; Ferron-Brady, Geraldine; Brouch, Maria; Montes de Oca, Rocio; Paul, Sofia; Holkova, Beata; Gupta, Ira; Kremer, Brandon E; Richardson, Paul.

Future Oncol ; 17(16): 1987-2003, 2021 06.

Artigo em Inglês | MEDLINE | ID: mdl-33682447

7.

Belantamab mafodotin for relapsed or refractory multiple myeloma (DREAMM-2): a two-arm, randomised, open-label, phase 2 study.

Lonial, Sagar; Lee, Hans C; Badros, Ashraf; Trudel, Suzanne; Nooka, Ajay K; Chari, Ajai; Abdallah, Al-Ola; Callander, Natalie; Lendvai, Nikoletta; Sborov, Douglas; Suvannasankha, Attaya; Weisel, Katja; Karlin, Lionel; Libby, Edward; Arnulf, Bertrand; Facon, Thierry; Hulin, Cyrille; Kortüm, K Martin; Rodríguez-Otero, Paula; Usmani, Saad Z; Hari, Parameswaran; Baz, Rachid; Quach, Hang; Moreau, Philippe; Voorhees, Peter M; Gupta, Ira; Hoos, Axel; Zhi, Eric; Baron, January; Piontek, Trisha; Lewis, Eric; Jewell, Roxanne C; Dettman, Elisha J; Popat, Rakesh; Esposti, Simona Degli; Opalinska, Joanna; Richardson, Paul; Cohen, Adam D.

Lancet Oncol ; 21(2): 207-221, 2020 02.

Artigo em Inglês | MEDLINE | ID: mdl-31859245

8.

Safety and efficacy of selinexor in relapsed or refractory multiple myeloma and Waldenstrom macroglobulinemia.

Chen, Christine; Siegel, David; Gutierrez, Martin; Jacoby, Meagan; Hofmeister, Craig C; Gabrail, Nashat; Baz, Rachid; Mau-Sorensen, Morten; Berdeja, Jesus G; Savona, Michael; Savoie, Lynn; Trudel, Suzanne; Areethamsirikul, Nuchanan; Unger, T J; Rashal, Tami; Hanke, Tim; Kauffman, Michael; Shacham, Sharon; Reece, Donna.

Blood ; 131(8): 855-863, 2018 02 22.

Artigo em Inglês | MEDLINE | ID: mdl-29203585

9.

Belantamab mafodotin in the treatment of relapsed or refractory multiple myeloma.

Sheikh, Semira; Lebel, Eyal; Trudel, Suzanne.

Future Oncol ; 16(34): 2783-2798, 2020 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-32875817

10.

Targeting B-cell maturation antigen with GSK2857916 antibody-drug conjugate in relapsed or refractory multiple myeloma (BMA117159): a dose escalation and expansion phase 1 trial.

Trudel, Suzanne; Lendvai, Nikoletta; Popat, Rakesh; Voorhees, Peter M; Reeves, Brandi; Libby, Edward N; Richardson, Paul G; Anderson, Larry D; Sutherland, Heather J; Yong, Kwee; Hoos, Axel; Gorczyca, Michele M; Lahiri, Soumi; He, Zangdong; Austin, Daren J; Opalinska, Joanna B; Cohen, Adam D.

Lancet Oncol ; 19(12): 1641-1653, 2018 12.

Artigo em Inglês | MEDLINE | ID: mdl-30442502

11.

Initial genome sequencing and analysis of multiple myeloma.

Chapman, Michael A; Lawrence, Michael S; Keats, Jonathan J; Cibulskis, Kristian; Sougnez, Carrie; Schinzel, Anna C; Harview, Christina L; Brunet, Jean-Philippe; Ahmann, Gregory J; Adli, Mazhar; Anderson, Kenneth C; Ardlie, Kristin G; Auclair, Daniel; Baker, Angela; Bergsagel, P Leif; Bernstein, Bradley E; Drier, Yotam; Fonseca, Rafael; Gabriel, Stacey B; Hofmeister, Craig C; Jagannath, Sundar; Jakubowiak, Andrzej J; Krishnan, Amrita; Levy, Joan; Liefeld, Ted; Lonial, Sagar; Mahan, Scott; Mfuko, Bunmi; Monti, Stefano; Perkins, Louise M; Onofrio, Robb; Pugh, Trevor J; Rajkumar, S Vincent; Ramos, Alex H; Siegel, David S; Sivachenko, Andrey; Stewart, A Keith; Trudel, Suzanne; Vij, Ravi; Voet, Douglas; Winckler, Wendy; Zimmerman, Todd; Carpten, John; Trent, Jeff; Hahn, William C; Garraway, Levi A; Meyerson, Matthew; Lander, Eric S; Getz, Gad; Golub, Todd R.

Nature ; 471(7339): 467-72, 2011 Mar 24.

Artigo em Inglês | MEDLINE | ID: mdl-21430775

12.

Tyrosine phosphorylation of the Lyn Src homology 2 (SH2) domain modulates its binding affinity and specificity.

Jin, Lily L; Wybenga-Groot, Leanne E; Tong, Jiefei; Taylor, Paul; Minden, Mark D; Trudel, Suzanne; McGlade, C Jane; Moran, Michael F.

Mol Cell Proteomics ; 14(3): 695-706, 2015 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-25587033

13.

Differential regulation of FGFR3 by PTPN1 and PTPN2.

St-Germain, Jonathan R; Taylor, Paul; Zhang, Wen; Li, Zhihua; Ketela, Troy; Moffat, Jason; Neel, Benjamin G; Trudel, Suzanne; Moran, Michael F.

Proteomics ; 15(2-3): 419-33, 2015 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-25311528

14.

Phase I-II trial of oral cyclophosphamide, prednisone and lenalidomide for the treatment of patients with relapsed and refractory multiple myeloma.

Reece, Donna E; Masih-Khan, Esther; Atenafu, Eshetu G; Jimenez-Zepeda, Victor H; Anglin, Peter; Chen, Christine; Kukreti, Vishal; Mikhael, Joseph R; Trudel, Suzanne.

Br J Haematol ; 168(1): 46-54, 2015 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-25146584

15.

Incorporating isatuximab in the treatment of multiple myeloma.

Trudel, Suzanne.

Lancet ; 394(10214): 2045-2047, 2019 12 07.

Artigo em Inglês | MEDLINE | ID: mdl-31735559

16.

A randomized phase 3 trial of thalidomide and prednisone as maintenance therapy after ASCT in patients with MM with a quality-of-life assessment: the National Cancer Institute of Canada Clinicals Trials Group Myeloma 10 Trial.

Stewart, A Keith; Trudel, Suzanne; Bahlis, Nizar J; White, Darrell; Sabry, Waleed; Belch, Andrew; Reiman, Tony; Roy, Jean; Shustik, Chaim; Kovacs, Michael J; Rubinger, Morel; Cantin, Guy; Song, Kevin; Tompkins, Kirsty A; Marcellus, Deb C; Lacy, Martha Q; Sussman, Jonathan; Reece, Donna; Brundage, Michael; Harnett, Erica L; Shepherd, Lois; Chapman, Judy-Anne W; Meyer, Ralph M.

Blood ; 121(9): 1517-23, 2013 Feb 28.

Artigo em Inglês | MEDLINE | ID: mdl-23297129

17.

Tolerability of Velcade (Bortezomib) subcutaneous administration using a maximum volume of 3 mL per injection site.

Ng, Pamela; Incekol, Diana; Lee, Roy; Paisley, Emma; Dara, Celina; Brandle, Ian; Kaufman, Marina; Chen, Christine; Trudel, Suzanne; Tiedemann, Rodger; Reece, Donna; Kukreti, Vishal.

J Oncol Pharm Pract ; 21(4): 285-92, 2015 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-24781451

18.

Autologous stem cell transplant is an effective therapy for carefully selected patients with AL amyloidosis: experience of a single institution.

Jimenez-Zepeda, Victor H; Franke, Norman; Reece, Donna E; Trudel, Suzanne; Chen, Christine; Delgado, Diego H; Winter, Andrew; Mikhael, Joseph R; Tiedemann, Rodger; Kukreti, Vishal.

Br J Haematol ; 164(5): 722-8, 2014 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-24266428

19.

A phase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma.

Siegel, David S; Martin, Thomas; Wang, Michael; Vij, Ravi; Jakubowiak, Andrzej J; Lonial, Sagar; Trudel, Suzanne; Kukreti, Vishal; Bahlis, Nizar; Alsina, Melissa; Chanan-Khan, Asher; Buadi, Francis; Reu, Frederic J; Somlo, George; Zonder, Jeffrey; Song, Kevin; Stewart, A Keith; Stadtmauer, Edward; Kunkel, Lori; Wear, Sandra; Wong, Alvin F; Orlowski, Robert Z; Jagannath, Sundar.

Blood ; 120(14): 2817-25, 2012 Oct 04.

Artigo em Inglês | MEDLINE | ID: mdl-22833546

20.

Oral ciclopirox olamine displays biological activity in a phase I study in patients with advanced hematologic malignancies.

Minden, Mark D; Hogge, Donna E; Weir, Scott J; Kasper, Jim; Webster, Debra A; Patton, Lavonne; Jitkova, Yulia; Hurren, Rose; Gronda, Marcela; Goard, Carolyn A; Rajewski, Lian G; Haslam, John L; Heppert, Kathleen E; Schorno, Kevin; Chang, Hong; Brandwein, Joseph M; Gupta, Vikas; Schuh, Andre C; Trudel, Suzanne; Yee, Karen W L; Reed, Gregory A; Schimmer, Aaron D.

Am J Hematol ; 89(4): 363-8, 2014 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-24273151

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