Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Transcriptional Control of Dendritic Cell Development.

Murphy, Theresa L; Grajales-Reyes, Gary E; Wu, Xiaodi; Tussiwand, Roxane; Briseño, Carlos G; Iwata, Arifumi; Kretzer, Nicole M; Durai, Vivek; Murphy, Kenneth M.

Annu Rev Immunol ; 34: 93-119, 2016 05 20.

Artigo em Inglês | MEDLINE | ID: mdl-26735697

2.

Dntt expression reveals developmental hierarchy and lineage specification of hematopoietic progenitors.

Klein, Fabian; Roux, Julien; Cvijetic, Grozdan; Rodrigues, Patrick Fernandes; von Muenchow, Lilly; Lubin, Ruth; Pelczar, Pawel; Yona, Simon; Tsapogas, Panagiotis; Tussiwand, Roxane.

Nat Immunol ; 23(4): 505-517, 2022 04.

Artigo em Inglês | MEDLINE | ID: mdl-35354960

3.

Homeostatic IL-13 in healthy skin directs dendritic cell differentiation to promote T_H2 and inhibit T_H17 cell polarization.

Mayer, Johannes U; Hilligan, Kerry L; Chandler, Jodie S; Eccles, David A; Old, Samuel I; Domingues, Rita G; Yang, Jianping; Webb, Greta R; Munoz-Erazo, Luis; Hyde, Evelyn J; Wakelin, Kirsty A; Tang, Shiau-Choot; Chappell, Sally C; von Daake, Sventja; Brombacher, Frank; Mackay, Charles R; Sher, Alan; Tussiwand, Roxane; Connor, Lisa M; Gallego-Ortega, David; Jankovic, Dragana; Le Gros, Graham; Hepworth, Matthew R; Lamiable, Olivier; Ronchese, Franca.

Nat Immunol ; 22(12): 1538-1550, 2021 12.

Artigo em Inglês | MEDLINE | ID: mdl-34795444

4.

Plasmacytoid dendritic cells turn red!

Tussiwand, Roxane.

Nat Immunol ; 24(4): 563-564, 2023 04.

Artigo em Inglês | MEDLINE | ID: mdl-36959295

5.

Distinct progenitor lineages contribute to the heterogeneity of plasmacytoid dendritic cells.

Rodrigues, Patrick Fernandes; Alberti-Servera, Llucia; Eremin, Anna; Grajales-Reyes, Gary E; Ivanek, Robert; Tussiwand, Roxane.

Nat Immunol ; 19(7): 711-722, 2018 07.

Artigo em Inglês | MEDLINE | ID: mdl-29925996

6.

Quality of TCR signaling determined by differential affinities of enhancers for the composite BATF-IRF4 transcription factor complex.

Iwata, Arifumi; Durai, Vivek; Tussiwand, Roxane; Briseño, Carlos G; Wu, Xiaodi; Grajales-Reyes, Gary E; Egawa, Takeshi; Murphy, Theresa L; Murphy, Kenneth M.

Nat Immunol ; 18(5): 563-572, 2017 05.

Artigo em Inglês | MEDLINE | ID: mdl-28346410

7.

Author Correction: Homeostatic IL-13 in healthy skin directs dendritic cell differentiation to promote T_H2 and inhibit T_H17 cell polarization.

Mayer, Johannes U; Hilligan, Kerry L; Chandler, Jodie S; Eccles, David A; Old, Samuel I; Domingues, Rita G; Yang, Jianping; Webb, Greta R; Munoz-Erazo, Luis; Hyde, Evelyn J; Wakelin, Kirsty A; Tang, Shiau-Choot; Chappell, Sally C; von Daake, Sventja; Brombacher, Frank; Mackay, Charles R; Sher, Alan; Tussiwand, Roxane; Connor, Lisa M; Gallego-Ortega, David; Jankovic, Dragana; Le Gros, Graham; Hepworth, Matthew R; Lamiable, Olivier; Ronchese, Franca.

Nat Immunol ; 23(6): 985, 2022 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-35418649

8.

Where's Waldo: Identifying DCs within Mononuclear Phagocytes during Inflammation.

Tussiwand, Roxane; Rodrigues, Patrick F.

Immunity ; 52(6): 892-894, 2020 06 16.

Artigo em Inglês | MEDLINE | ID: mdl-32553175

9.

Batf3 maintains autoactivation of Irf8 for commitment of a CD8α(+) conventional DC clonogenic progenitor.

Grajales-Reyes, Gary E; Iwata, Arifumi; Albring, Jörn; Wu, Xiaodi; Tussiwand, Roxane; Kc, Wumesh; Kretzer, Nicole M; Briseño, Carlos G; Durai, Vivek; Bagadia, Prachi; Haldar, Malay; Schönheit, Jörg; Rosenbauer, Frank; Murphy, Theresa L; Murphy, Kenneth M.

Nat Immunol ; 16(7): 708-17, 2015 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-26054719

10.

Klf4 expression in conventional dendritic cells is required for T helper 2 cell responses.

Tussiwand, Roxane; Everts, Bart; Grajales-Reyes, Gary E; Kretzer, Nicole M; Iwata, Arifumi; Bagaitkar, Juhi; Wu, Xiaodi; Wong, Rachel; Anderson, David A; Murphy, Theresa L; Pearce, Edward J; Murphy, Kenneth M.

Immunity ; 42(5): 916-28, 2015 May 19.

Artigo em Inglês | MEDLINE | ID: mdl-25992862

11.

Langerin+ DCs regulate innate IL-17 production in the oral mucosa during Candida albicans-mediated infection.

Sparber, Florian; Dolowschiak, Tamas; Mertens, Sarah; Lauener, Laura; Clausen, Björn E; Joller, Nicole; Stoitzner, Patrizia; Tussiwand, Roxane; LeibundGut-Landmann, Salomé.

PLoS Pathog ; 14(5): e1007069, 2018 05.

Artigo em Inglês | MEDLINE | ID: mdl-29782555

12.

Transcription factor Zeb2 regulates commitment to plasmacytoid dendritic cell and monocyte fate.

Wu, Xiaodi; Briseño, Carlos G; Grajales-Reyes, Gary E; Haldar, Malay; Iwata, Arifumi; Kretzer, Nicole M; Kc, Wumesh; Tussiwand, Roxane; Higashi, Yujiro; Murphy, Theresa L; Murphy, Kenneth M.

Proc Natl Acad Sci U S A ; 113(51): 14775-14780, 2016 12 20.

Artigo em Inglês | MEDLINE | ID: mdl-27930303

13.

Compensatory dendritic cell development mediated by BATF-IRF interactions.

Tussiwand, Roxane; Lee, Wan-Ling; Murphy, Theresa L; Mashayekhi, Mona; KC, Wumesh; Albring, Jörn C; Satpathy, Ansuman T; Rotondo, Jeffrey A; Edelson, Brian T; Kretzer, Nicole M; Wu, Xiaodi; Weiss, Leslie A; Glasmacher, Elke; Li, Peng; Liao, Wei; Behnke, Michael; Lam, Samuel S K; Aurthur, Cora T; Leonard, Warren J; Singh, Harinder; Stallings, Christina L; Sibley, L David; Schreiber, Robert D; Murphy, Kenneth M.

Nature ; 490(7421): 502-7, 2012 Oct 25.

Artigo em Inglês | MEDLINE | ID: mdl-22992524

14.

A stromal cell free culture system generates mouse pro-T cells that can reconstitute T-cell compartments in vivo.

Gehre, Nadine; Nusser, Anja; von Muenchow, Lilly; Tussiwand, Roxane; Engdahl, Corinne; Capoferri, Giuseppina; Bosco, Nabil; Ceredig, Rhodri; Rolink, Antonius G.

Eur J Immunol ; 45(3): 932-42, 2015 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-25408420

15.

Sexual dimorphism in skin immunity is mediated by an androgen-ILC2-dendritic cell axis.

Chi, Liang; Liu, Can; Gribonika, Inta; Gschwend, Julia; Corral, Dan; Han, Seong-Ji; Lim, Ai Ing; Rivera, Claudia A; Link, Verena M; Wells, Alexandria C; Bouladoux, Nicolas; Collins, Nicholas; Lima-Junior, Djalma S; Enamorado, Michel; Rehermann, Barbara; Laffont, Sophie; Guéry, Jean-Charles; Tussiwand, Roxane; Schneider, Christoph; Belkaid, Yasmine.

Science ; 384(6692): eadk6200, 2024 Apr 12.

Artigo em Inglês | MEDLINE | ID: mdl-38574174

16.

BAFF-R expression correlates with positive selection of immature B cells.

Tussiwand, Roxane; Rauch, Melanie; Flück, Lukas A; Rolink, Antonius G.

Eur J Immunol ; 42(1): 206-16, 2012 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-22028296

17.

pDC-like cells are pre-DC2 and require KLF4 to control homeostatic CD4 T cells.

Rodrigues, Patrick Fernandes; Kouklas, Athanasios; Cvijetic, Grozdan; Bouladoux, Nicolas; Mitrovic, Mladen; Desai, Jigar V; Lima-Junior, Djalma S; Lionakis, Michail S; Belkaid, Yasmine; Ivanek, Robert; Tussiwand, Roxane.

Sci Immunol ; 8(80): eadd4132, 2023 02 24.

Artigo em Inglês | MEDLINE | ID: mdl-36827419

18.

TGF-ß uncouples glycolysis and inflammation in macrophages and controls survival during sepsis.

Gauthier, Thierry; Yao, Chen; Dowdy, Tyrone; Jin, Wenwen; Lim, Yun-Ji; Patiño, Liliana C; Liu, Na; Ohlemacher, Shannon I; Bynum, Andrew; Kazmi, Rida; Bewley, Carole A; Mitrovic, Mladen; Martin, Daniel; Morell, Robert J; Eckhaus, Michael; Larion, Mioara; Tussiwand, Roxane; O'Shea, John J; Chen, WanJun.

Sci Signal ; 16(797): eade0385, 2023 08 08.

Artigo em Inglês | MEDLINE | ID: mdl-37552767

19.

Activation of the Flt3 signal transduction cascade rescues and enhances type I interferon-producing and dendritic cell development.

Onai, Nobuyuki; Obata-Onai, Aya; Tussiwand, Roxane; Lanzavecchia, Antonio; Manz, Markus G.

J Exp Med ; 203(1): 227-38, 2006 Jan 23.

Artigo em Inglês | MEDLINE | ID: mdl-16418395

20.

The preTCR-dependent DN3 to DP transition requires Notch signaling, is improved by CXCL12 signaling and is inhibited by IL-7 signaling.

Tussiwand, Roxane; Engdahl, Corinne; Gehre, Nadine; Bosco, Nabil; Ceredig, Rod; Rolink, Antonius G.

Eur J Immunol ; 41(11): 3371-80, 2011 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-21882187

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