Detalhe da pesquisa
1.
Pharmacokinetic and pharmacodynamic modeling of opioid-induced gastrointestinal side effects in patients receiving tapentadol IR and oxycodone IR.
Pharm Res
; 29(9): 2555-64, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22618801
2.
Pain relief and tolerability balance of immediate release tapentadol or oxycodone treatment for patients with moderate to severe osteoarthritis or low back pain.
Pain Med
; 13(9): 1110-20, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22845494
3.
Post hoc analyses of data from a 90-day clinical trial evaluating the tolerability and efficacy of tapentadol immediate release and oxycodone immediate release for the relief of moderate to severe pain in elderly and nonelderly patients.
Pain Res Manag
; 16(4): 245-51, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22059194
4.
Efficacy and tolerability of tapentadol immediate release and oxycodone HCl immediate release in patients awaiting primary joint replacement surgery for end-stage joint disease: a 10-day, phase III, randomized, double-blind, active- and placebo-controlled study.
Clin Ther
; 31(2): 260-71, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19302899
5.
Bioavailability study of a 1200 mg miconazole nitrate vaginal ovule in healthy female adults.
J Clin Pharmacol
; 42(1): 52-60, 2002 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-11808824
6.
Bowel function after tapentadol and oxycodone immediate release (IR) treatment in patients with low back or osteoarthritis pain.
Clin J Pain
; 29(8): 664-72, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23835764
7.
Dose-response relationship after single oral dose administrations of morphine and oxycodone using laser-evoked potentials on UVB- and capsaicin-irritated skin in healthy male subjects.
Pain
; 153(8): 1648-1656, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22703892
8.
Tapentadol immediate release: a new treatment option for acute pain management.
J Pain Res
; 3: 1-9, 2010 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21197304
9.
Evaluation of study discontinuations with tapentadol inmmediate release and oxycodone immediate release in patients with low back or osteoarthritis pain.
J Opioid Manag
; 6(3): 169-79, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20642246
10.
Effects of acetaminophen, naproxen, and acetylsalicylic acid on tapentadol pharmacokinetics: results of two randomized, open-label, crossover, drug-drug interaction studies.
Pharmacotherapy
; 30(1): 25-34, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20030470
11.
A randomized, double-blind, phase III study comparing multiple doses of tapentadol IR, oxycodone IR, and placebo for postoperative (bunionectomy) pain.
Curr Med Res Opin
; 25(3): 765-76, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19203298
12.
Tolerability of tapentadol immediate release in patients with lower back pain or osteoarthritis of the hip or knee over 90 days: a randomized, double-blind study.
Curr Med Res Opin
; 25(5): 1095-104, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19301989
13.
A randomized, double-blind, placebo-controlled phase 3 study of the relative efficacy and tolerability of tapentadol IR and oxycodone IR for acute pain.
Curr Med Res Opin
; 25(6): 1551-61, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19445652
14.
Tapentadol hydrochloride: a next-generation, centrally acting analgesic with two mechanisms of action in a single molecule.
Drugs Today (Barc)
; 45(7): 483-96, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19834626
15.
The efficacy and tolerability of multiple-dose tapentadol immediate release for the relief of acute pain following orthopedic (bunionectomy) surgery .
Curr Med Res Opin
; 24(11): 3185-96, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18851776