RESUMO
Report about 2 children affected with the cat scratch disease or lymphoreticulosis. The AA. discuss some etiological and clinic features of the malady, especially emphasizing the typical anatomopathological findings, which in the majority of the occurrences, allow the actual diagnosis. This is a disease of low incidence, but must be bear in mind when dealing with any cervical lump.
Assuntos
Doença da Arranhadura de Gato/diagnóstico , Vértebras Cervicais/fisiopatologia , Doença da Arranhadura de Gato/microbiologia , Doença da Arranhadura de Gato/fisiopatologia , Criança , Diagnóstico Diferencial , Epitélio , Bacilos Gram-Positivos/isolamento & purificação , Granuloma de Células Gigantes/diagnóstico , Granuloma de Células Gigantes/cirurgia , Humanos , Osso Hioide/cirurgia , Masculino , Doenças Mandibulares/diagnóstico , Doenças Mandibulares/fisiopatologia , Neutrófilos/citologiaRESUMO
Variations in class 2/3 (PorB) proteins form the basis for meningococcal serotyping. Antibodies against these proteins are bactericidal, making serotyping results useful not only for epidemiological surveillance of meningococcal disease but also for identifying potential vaccine components. A total of 20 to 60% of meningococcal B and C isolates from any given population are nontypeable (NT) using a panel of monoclonal antibodies. To analyze the mechanisms responsible for the nonserotypeability characteristic in Neisseria meningitidis, we (i) established the nucleotide sequences of porB gene in 146 meningococcal strains (95 not recognized by the serotyping panel), (ii) identified 18 new allelic variants of the porB gene, (iii) correlated allelic variants with serotypes, (iv) suggest the nontypeability characteristic in those 95 NT strains, and (v) reject the possibility of variation in the levels of PorB expression.