Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab.

Riaz, Nadeem; Havel, Jonathan J; Makarov, Vladimir; Desrichard, Alexis; Urba, Walter J; Sims, Jennifer S; Hodi, F Stephen; Martín-Algarra, Salvador; Mandal, Rajarsi; Sharfman, William H; Bhatia, Shailender; Hwu, Wen-Jen; Gajewski, Thomas F; Slingluff, Craig L; Chowell, Diego; Kendall, Sviatoslav M; Chang, Han; Shah, Rachna; Kuo, Fengshen; Morris, Luc G T; Sidhom, John-William; Schneck, Jonathan P; Horak, Christine E; Weinhold, Nils; Chan, Timothy A.

Cell ; 171(4): 934-949.e16, 2017 Nov 02.

Artigo em Inglês | MEDLINE | ID: mdl-29033130

2.

Neoantigen T-Cell Receptor Gene Therapy in Pancreatic Cancer.

Leidner, Rom; Sanjuan Silva, Nelson; Huang, Huayu; Sprott, David; Zheng, Chunhong; Shih, Yi-Ping; Leung, Amy; Payne, Roxanne; Sutcliffe, Kim; Cramer, Julie; Rosenberg, Steven A; Fox, Bernard A; Urba, Walter J; Tran, Eric.

N Engl J Med ; 386(22): 2112-2119, 2022 06 02.

Artigo em Inglês | MEDLINE | ID: mdl-35648703

3.

Galunisertib plus neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer: a single-arm, phase 2 trial.

Yamazaki, Tomoko; Gunderson, Andrew J; Gilchrist, Miranda; Whiteford, Mark; Kiely, Maria X; Hayman, Amanda; O'Brien, David; Ahmad, Rehan; Manchio, Jeffrey V; Fox, Nathaniel; McCarty, Kayla; Phillips, Michaela; Brosnan, Evelyn; Vaccaro, Gina; Li, Rui; Simon, Miklos; Bernstein, Eric; McCormick, Mary; Yamasaki, Lena; Wu, Yaping; Drokin, Ashley; Carnahan, Trevor; To, Yy; Redmond, William L; Lee, Brian; Louie, Jeannie; Hansen, Eric; Solhjem, Matthew C; Cramer, Julie; Urba, Walter J; Gough, Michael J; Crittenden, Marka R; Young, Kristina H.

Lancet Oncol ; 23(9): 1189-1200, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-35952709

4.

Multiplex immunofluorescence to measure dynamic changes in tumor-infiltrating lymphocytes and PD-L1 in early-stage breast cancer.

Sanchez, Katherine; Kim, Isaac; Chun, Brie; Pucilowska, Joanna; Redmond, William L; Urba, Walter J; Martel, Maritza; Wu, Yaping; Campbell, Mary; Sun, Zhaoyu; Grunkemeier, Gary; Chang, Shu Ching; Bernard, Brady; Page, David B.

Breast Cancer Res ; 23(1): 2, 2021 01 07.

Artigo em Inglês | MEDLINE | ID: mdl-33413574

5.

Neoantigen T-Cell Receptor Gene Therapy in Pancreatic Cancer. Reply.

Tran, Eric; Urba, Walter J; Leidner, Rom.

N Engl J Med ; 387(6): 574, 2022 08 11.

Artigo em Inglês | MEDLINE | ID: mdl-35947721

6.

A Milestone for CAR T Cells.

Tran, Eric; Longo, Dan L; Urba, Walter J.

N Engl J Med ; 377(26): 2593-2596, 2017 12 28.

Artigo em Inglês | MEDLINE | ID: mdl-29226781

7.

Science gone translational: the OX40 agonist story.

Weinberg, Andrew D; Morris, Nicholas P; Kovacsovics-Bankowski, Magdalena; Urba, Walter J; Curti, Brendan D.

Immunol Rev ; 244(1): 218-31, 2011 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-22017441

8.

Unmasking PD-1 Resistance by Next-Generation Sequencing.

Bifulco, Carlo B; Urba, Walter J.

N Engl J Med ; 375(9): 888-9, 2016 Sep 01.

Artigo em Inglês | MEDLINE | ID: mdl-27579640

9.

Cross-presentation of viral antigens in dribbles leads to efficient activation of virus-specific human memory T cells.

Ye, Wei; Xing, Yun; Paustian, Christopher; van de Ven, Rieneke; Moudgil, Tarsem; Hilton, Traci L; Fox, Bernard A; Urba, Walter J; Zhao, Wei; Hu, Hong-Ming.

J Transl Med ; 12: 100, 2014 Apr 16.

Artigo em Inglês | MEDLINE | ID: mdl-24735498

10.

Pertuzumab Plus Trastuzumab in Patients With Biliary Tract Cancer With ERBB2/3 Alterations: Results From the Targeted Agent and Profiling Utilization Registry Study.

Cannon, Timothy L; Rothe, Michael; Mangat, Pam K; Garrett-Mayer, Elizabeth; Chiu, Vi K; Hwang, Jimmy; Vijayvergia, Namrata; Alese, Olatunji B; Dib, Elie G; Duvivier, Herbert L; Klute, Kelsey A; Sahai, Vaibhav; Ahn, Eugene R; Bedano, Pablo; Behl, Deepti; Sinclair, Sarah; Thota, Ramya; Urba, Walter J; Yang, Eddy S; Grantham, Gina N; Hinshaw, Dominique C; Gregory, Abigail; Halabi, Susan; Schilsky, Richard L.

J Clin Oncol ; : JCO2302078, 2024 May 15.

Artigo em Inglês | MEDLINE | ID: mdl-38748939

11.

Improved survival with ipilimumab in patients with metastatic melanoma.

Hodi, F Stephen; O'Day, Steven J; McDermott, David F; Weber, Robert W; Sosman, Jeffrey A; Haanen, John B; Gonzalez, Rene; Robert, Caroline; Schadendorf, Dirk; Hassel, Jessica C; Akerley, Wallace; van den Eertwegh, Alfons J M; Lutzky, Jose; Lorigan, Paul; Vaubel, Julia M; Linette, Gerald P; Hogg, David; Ottensmeier, Christian H; Lebbé, Celeste; Peschel, Christian; Quirt, Ian; Clark, Joseph I; Wolchok, Jedd D; Weber, Jeffrey S; Tian, Jason; Yellin, Michael J; Nichol, Geoffrey M; Hoos, Axel; Urba, Walter J.

N Engl J Med ; 363(8): 711-23, 2010 Aug 19.

Artigo em Inglês | MEDLINE | ID: mdl-20525992

12.

The additional facet of immunoscore: immunoprofiling as a possible predictive tool for cancer treatment.

Ascierto, Paolo A; Capone, Mariaelena; Urba, Walter J; Bifulco, Carlo B; Botti, Gerardo; Lugli, Alessandro; Marincola, Francesco M; Ciliberto, Gennaro; Galon, Jérôme; Fox, Bernard A.

J Transl Med ; 11: 54, 2013 Mar 03.

Artigo em Inglês | MEDLINE | ID: mdl-23452415

13.

Cancer's Dark Matter: Lighting the Abyss Unveils Universe of New Therapies.

Fox, Bernard A; Urba, Walter J; Jensen, Shawn M; Page, David B; Curti, Brendan D; Sanborn, Rachel E; Leidner, Rom S.

Clin Cancer Res ; 29(12): 2173-2175, 2023 06 13.

Artigo em Inglês | MEDLINE | ID: mdl-37040070

14.

Cobimetinib Plus Vemurafenib in Patients With Solid Tumors With BRAF Mutations: Results From the Targeted Agent and Profiling Utilization Registry Study.

Meric-Bernstam, Funda; Rothe, Michael; Mangat, Pam K; Garrett-Mayer, Elizabeth; Gutierrez, Rodolfo; Ahn, Eugene R; Cannon, Timothy L; Powell, Steven; Krauss, John C; Reynolds, Christopher M; von Mehren, Margaret; Behl, Deepti; Calfa, Carmen J; Duvivier, Herbert L; Kaplan, Henry G; Livingston, Michael B; Sharma, Manish R; Urba, Walter J; Grantham, Gina N; Hinshaw, Dominique C; Gregory, Abigail; Halabi, Susan; Schilsky, Richard L.

JCO Precis Oncol ; 7: e2300385, 2023 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-38096472

15.

A phase Ib trial of pembrolizumab plus paclitaxel or flat-dose capecitabine in 1st/2nd line metastatic triple-negative breast cancer.

Page, David B; Pucilowska, Joanna; Chun, Brie; Kim, Isaac; Sanchez, Katherine; Moxon, Nicole; Mellinger, Staci; Wu, Yaping; Koguchi, Yoshinobu; Conrad, Valerie; Redmond, William L; Martel, Maritza; Sun, Zhaoyu; Campbell, Mary B; Conlin, Alison; Acheson, Anupama; Basho, Reva; McAndrew, Philomena; El-Masry, Mary; Park, Dorothy; Bennetts, Laura; Seitz, Robert S; Nielsen, Tyler J; McGregor, Kimberly; Rajamanickam, Venkatesh; Bernard, Brady; Urba, Walter J; McArthur, Heather L.

NPJ Breast Cancer ; 9(1): 53, 2023 Jun 21.

Artigo em Inglês | MEDLINE | ID: mdl-37344474

16.

Combination Dabrafenib and Trametinib Versus Combination Nivolumab and Ipilimumab for Patients With Advanced BRAF-Mutant Melanoma: The DREAMseq Trial-ECOG-ACRIN EA6134.

Atkins, Michael B; Lee, Sandra J; Chmielowski, Bartosz; Tarhini, Ahmad A; Cohen, Gary I; Truong, Thach-Giao; Moon, Helen H; Davar, Diwakar; O'Rourke, Mark; Stephenson, Joseph J; Curti, Brendan D; Urba, Walter J; Brell, Joanna M; Funchain, Pauline; Kendra, Kari L; Ikeguchi, Alexandra P; Jaslowski, Anthony; Bane, Charles L; Taylor, Mark A; Bajaj, Madhuri; Conry, Robert M; Ellis, Robert J; Logan, Theodore F; Laudi, Noel; Sosman, Jeffrey A; Crockett, David G; Pecora, Andrew L; Okazaki, Ian J; Reganti, Sowjanya; Chandra, Sunandana; Guild, Samantha; Chen, Helen X; Streicher, Howard Z; Wolchok, Jedd D; Ribas, Antoni; Kirkwood, John M.

J Clin Oncol ; 41(2): 186-197, 2023 01 10.

Artigo em Inglês | MEDLINE | ID: mdl-36166727

17.

An open-label, phase 2 trial of RPI.4610 (Angiozyme) in the treatment of metastatic breast cancer.

Morrow, Phuong Khanh; Murthy, Rashmi K; Ensor, Joe D; Gordon, Gilad S; Margolin, Kim A; Elias, Anthony D; Urba, Walter J; Weng, David E; Rugo, Hope S; Hortobagyi, Gabriel N.

Cancer ; 118(17): 4098-104, 2012 Sep 01.

Artigo em Inglês | MEDLINE | ID: mdl-22281842

18.

Integrating new therapies in the treatment of advanced melanoma.

Curti, Brendan D; Urba, Walter J.

Curr Treat Options Oncol ; 13(3): 327-39, 2012 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-22743761

19.

Changes in T-cell subsets and clonal repertoire during chemoimmunotherapy with pembrolizumab and paclitaxel or capecitabine for metastatic triple-negative breast cancer.

Chun, Brie; Pucilowska, Joanna; Chang, ShuChing; Kim, Isaac; Nikitin, Benjamin; Koguchi, Yoshinobu; Redmond, William L; Bernard, Brady; Rajamanickam, Venkatesh; Polaske, Nathan; Fields, Paul A; Conrad, Valerie; Schmidt, Mark; Urba, Walter J; Conlin, Alison K; McArthur, Heather L; Page, David B.

J Immunother Cancer ; 10(1)2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-35086949

20.

CD122+CD8+ Treg suppress vaccine-induced antitumor immune responses in lymphodepleted mice.

Wang, Li-Xin; Li, Yuhuan; Yang, Guojun; Pang, Pui-yi; Haley, Dan; Walker, Edwin B; Urba, Walter J; Hu, Hong-Ming.

Eur J Immunol ; 40(5): 1375-85, 2010 May.

Artigo em Inglês | MEDLINE | ID: mdl-20186876

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