Detalhe da pesquisa
1.
"Stripe" transcription factors provide accessibility to co-binding partners in mammalian genomes.
Mol Cell
; 82(18): 3398-3411.e11, 2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35863348
2.
Cancer-associated polybromo-1 bromodomain 4 missense variants variably impact bromodomain ligand binding and cell growth suppression.
J Biol Chem
; 300(4): 107146, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38460939
3.
Advanced computational analysis of CD40LG variants in atypical X-linked hyper-IgM syndrome.
Clin Immunol
; 253: 109692, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37433422
4.
Effects of Subnormothermic Regulated Hepatic Reperfusion on Mitochondrial and Transcriptomic Profiles in a Porcine Model.
Ann Surg
; 277(2): e366-e375, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34387201
5.
SASH3 variants cause a novel form of X-linked combined immunodeficiency with immune dysregulation.
Blood
; 138(12): 1019-1033, 2021 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33876203
6.
Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers.
Genes Dev
; 29(1): 7-22, 2015 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25504365
7.
A GATA6-centred gene regulatory network involving HNFs and ΔNp63 controls plasticity and immune escape in pancreatic cancer.
Gut
; 71(4): 766-777, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33846140
8.
Computational modeling reveals key molecular properties and dynamic behavior of disruptor of telomeric silencing 1-like (DOT1L) and partnering complexes involved in leukemogenesis.
Proteins
; 90(1): 282-298, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34414607
9.
Structural bioinformatics enhances mechanistic interpretation of genomic variation, demonstrated through the analyses of 935 distinct RAS family mutations.
Bioinformatics
; 37(10): 1367-1375, 2021 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33226070
10.
SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer.
Proc Natl Acad Sci U S A
; 116(47): 23534-23541, 2019 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31591207
11.
Impact of integrated translational research on clinical exome sequencing.
Genet Med
; 23(3): 498-507, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33144682
12.
Inorganic arsenic promotes luminal to basal transition and metastasis of breast cancer.
FASEB J
; 34(12): 16034-16048, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33047385
13.
ErbB3-binding protein 1 (EBP1) represses HNF4α-mediated transcription and insulin secretion in pancreatic ß-cells.
J Biol Chem
; 294(38): 13983-13994, 2019 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31362984
14.
Intrinsically disordered chromatin protein NUPR1 binds to the C-terminal region of Polycomb RING1B.
Proc Natl Acad Sci U S A
; 114(31): E6332-E6341, 2017 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28720707
15.
Variant anatomy of the biliary system as a cause of pancreatic and peri-ampullary cancers.
HPB (Oxford)
; 22(12): 1675-1685, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32336556
16.
Modeling post-translational modifications and cancer-associated mutations that impact the heterochromatin protein 1α-importin α heterodimers.
Proteins
; 87(11): 904-916, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31152607
17.
P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts.
Gastroenterology
; 154(8): 2209-2221.e14, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29454793
18.
Molecular characterization of known and novel ACVR1 variants in phenotypes of aberrant ossification.
Am J Med Genet A
; 179(9): 1764-1777, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31240838
19.
A Novel Kleefstra Syndrome-associated Variant That Affects the Conserved TPLX Motif within the Ankyrin Repeat of EHMT1 Leads to Abnormal Protein Folding.
J Biol Chem
; 292(9): 3866-3876, 2017 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28057753
20.
The Role of the Histone Methyltransferase Enhancer of Zeste Homolog 2 (EZH2) in the Pathobiological Mechanisms Underlying Inflammatory Bowel Disease (IBD).
J Biol Chem
; 292(2): 706-722, 2017 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27909059