Detalhe da pesquisa
1.
A novel Tetrahymena thermophila sterol C-22 desaturase belongs to the fatty acid hydroxylase/desaturase superfamily.
J Biol Chem
; 298(10): 102397, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35988640
2.
Functional characterization of the first lipoyl-relay pathway from a parasitic protozoan.
Mol Microbiol
; 117(6): 1352-1365, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35484915
3.
Genome-wide Transcriptional Analysis of Tetrahymena thermophila Response to Exogenous Cholesterol.
J Eukaryot Microbiol
; 67(2): 209-222, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31705733
4.
Structural determinant of functionality in acyl lipid desaturases.
J Lipid Res
; 59(10): 1871-1879, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30087203
5.
Lipoic acid metabolism in Trypanosoma cruzi as putative target for chemotherapy.
Exp Parasitol
; 186: 17-23, 2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-29409741
6.
Biosynthesis of very long chain fatty acids in Trypanosoma cruzi.
Parasitol Res
; 114(1): 265-71, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25339514
7.
The Sterol-C7 desaturase from the ciliate Tetrahymena thermophila is a Rieske Oxygenase, which is highly conserved in animals.
Mol Biol Evol
; 30(7): 1630-43, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23603937
8.
Synergistic effect of inhibitors of fatty acid desaturases on Trypanosoma parasites.
Parasitol Res
; 2013 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23797276
9.
A novel sterol desaturase-like protein promoting dealkylation of phytosterols in Tetrahymena thermophila.
Eukaryot Cell
; 10(3): 423-34, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21257793
10.
Stearoyl-CoA desaturase is an essential enzyme for the parasitic protist Trypanosoma brucei.
Biochem Biophys Res Commun
; 412(2): 286-90, 2011 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21820408
11.
Phagocytic and pinocytic uptake of cholesterol in Tetrahymena thermophila impact differently on gene regulation for sterol homeostasis.
Sci Rep
; 11(1): 9067, 2021 04 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33907281
12.
C-5(6) sterol desaturase from tetrahymena thermophila: Gene identification and knockout, sequence analysis, and comparison to other C-5(6) sterol desaturases.
Eukaryot Cell
; 8(8): 1287-97, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19525418
13.
Elongation of polyunsaturated fatty acids in trypanosomatids.
FEBS J
; 274(1): 264-74, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17222186
14.
Functional characterization of front-end desaturases from trypanosomatids depicts the first polyunsaturated fatty acid biosynthetic pathway from a parasitic protozoan.
FEBS J
; 273(2): 271-80, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16403015
15.
The malate dehydrogenase isoforms from Trypanosoma brucei: subcellular localization and differential expression in bloodstream and procyclic forms.
Int J Parasitol
; 36(3): 295-307, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16321390
16.
Sterol metabolism in the filasterean Capsaspora owczarzaki has features that resemble both fungi and animals.
Open Biol
; 6(7)2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27383626
17.
Acquisition and biosynthesis of saturated and unsaturated fatty acids by trypanosomatids.
Mol Biochem Parasitol
; 196(1): 61-70, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24726787
18.
Characterization of bifunctional sphingolipid Δ4-desaturases/C4-hydroxylases of trypanosomatids by liquid chromatography-electrospray tandem mass spectrometry.
Mol Biochem Parasitol
; 184(1): 29-38, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22542487
19.
Highly specific methyl-end fatty-acid desaturases of trypanosomatids.
Mol Biochem Parasitol
; 175(2): 126-32, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20974196
20.
Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target.
PLoS One
; 5(12): e14239, 2010 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-21151902