Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

PLAAT1 deficiency alleviates high-fat diet-induced hepatic lipid accumulation in mice.

Rahman, S M Khaledur; Sasaki, Sumire; Uyama, Toru; Hussain, Zahir; Sikder, Mohammad Mamun; Saiga, Hiroyuki; Ohmura-Hoshino, Mari; Ohta, Ken-Ichi; Miki, Yoshimi; Hoshino, Katsuaki; Ueno, Masaki; Murakami, Makoto; Ueda, Natsuo.

FASEB J ; 37(7): e23032, 2023 07.

Artigo em Inglês | MEDLINE | ID: mdl-37330992

2.

Roles of Endocannabinoids and Endocannabinoid-Like Molecules in Energy Homeostasis and Metabolic Regulation: A Nutritional Perspective.

Rahman, S M Khaledur; Uyama, Toru; Hussain, Zahir; Ueda, Natsuo.

Annu Rev Nutr ; 41: 177-202, 2021 10 11.

Artigo em Inglês | MEDLINE | ID: mdl-34115519

3.

Involvement of the Î³ Isoform of cPLA₂ in the Biosynthesis of Bioactive N-Acylethanolamines.

Guo, Yiman; Uyama, Toru; Rahman, S M Khaledur; Sikder, Mohammad Mamun; Hussain, Zahir; Tsuboi, Kazuhito; Miyake, Minoru; Ueda, Natsuo.

Molecules ; 26(17)2021 Aug 27.

Artigo em Inglês | MEDLINE | ID: mdl-34500646

4.

Phosphatidylserine-stimulated production of N-acyl-phosphatidylethanolamines by Ca²⁺-dependent N-acyltransferase.

Hussain, Zahir; Uyama, Toru; Kawai, Katsuhisa; Binte Mustafiz, Smriti Sultana; Tsuboi, Kazuhito; Araki, Nobukazu; Ueda, Natsuo.

Biochim Biophys Acta Mol Cell Biol Lipids ; 1863(5): 493-502, 2018 May.

Artigo em Inglês | MEDLINE | ID: mdl-29447909

5.

A quantitative study on splice variants of N-acylethanolamine acid amidase in human prostate cancer cells and other cells.

Sakura, Yuma; Tsuboi, Kazuhito; Uyama, Toru; Zhang, Xia; Taoka, Rikiya; Sugimoto, Mikio; Kakehi, Yoshiyuki; Ueda, Natsuo.

Biochim Biophys Acta ; 1861(12 Pt A): 1951-1958, 2016 12.

Artigo em Inglês | MEDLINE | ID: mdl-27693242

6.

Calcium-dependent generation of N-acylethanolamines and lysophosphatidic acids by glycerophosphodiesterase GDE7.

Rahman, Iffat Ara Sonia; Tsuboi, Kazuhito; Hussain, Zahir; Yamashita, Ryouhei; Okamoto, Yoko; Uyama, Toru; Yamazaki, Naoshi; Tanaka, Tamotsu; Tokumura, Akira; Ueda, Natsuo.

Biochim Biophys Acta ; 1861(12 Pt A): 1881-1892, 2016 12.

Artigo em Inglês | MEDLINE | ID: mdl-27637550

7.

Mammalian enzymes responsible for the biosynthesis of N-acylethanolamines.

Hussain, Zahir; Uyama, Toru; Tsuboi, Kazuhito; Ueda, Natsuo.

Biochim Biophys Acta Mol Cell Biol Lipids ; 1862(12): 1546-1561, 2017 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-28843504

8.

Comparative analyses of isoforms of the calcium-independent phosphatidylethanolamine N-acyltransferase PLAAT-1 in humans and mice.

Hussain, Zahir; Uyama, Toru; Kawai, Katsuhisa; Rahman, Iffat Ara Sonia; Tsuboi, Kazuhito; Araki, Nobukazu; Ueda, Natsuo.

J Lipid Res ; 57(11): 2051-2060, 2016 11.

Artigo em Inglês | MEDLINE | ID: mdl-27623847

9.

Interaction of Phospholipase A/Acyltransferase-3 with Pex19p: A POSSIBLE INVOLVEMENT IN THE DOWN-REGULATION OF PEROXISOMES.

Uyama, Toru; Kawai, Katsuhisa; Kono, Nozomu; Watanabe, Masahiro; Tsuboi, Kazuhito; Inoue, Tomohito; Araki, Nobukazu; Arai, Hiroyuki; Ueda, Natsuo.

J Biol Chem ; 290(28): 17520-34, 2015 Jul 10.

Artigo em Inglês | MEDLINE | ID: mdl-26018079

10.

Glycerophosphodiesterase GDE4 as a novel lysophospholipase D: a possible involvement in bioactive N-acylethanolamine biosynthesis.

Tsuboi, Kazuhito; Okamoto, Yoko; Rahman, Iffat Ara Sonia; Uyama, Toru; Inoue, Tomohito; Tokumura, Akira; Ueda, Natsuo.

Biochim Biophys Acta ; 1851(5): 537-48, 2015 May.

Artigo em Inglês | MEDLINE | ID: mdl-25596343

11.

Involvement of phospholipase A/acyltransferase-1 in N-acylphosphatidylethanolamine generation.

Uyama, Toru; Inoue, Manami; Okamoto, Yoko; Shinohara, Naoki; Tai, Tatsuya; Tsuboi, Kazuhito; Inoue, Tomohito; Tokumura, Akira; Ueda, Natsuo.

Biochim Biophys Acta ; 1831(12): 1690-701, 2013 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-23994608

12.

New players in the fatty acyl ethanolamide metabolism.

Rahman, Iffat Ara Sonia; Tsuboi, Kazuhito; Uyama, Toru; Ueda, Natsuo.

Pharmacol Res ; 86: 1-10, 2014 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-24747663

13.

Regulation of peroxisomal lipid metabolism by catalytic activity of tumor suppressor H-rev107.

Uyama, Toru; Ichi, Ikuyo; Kono, Nozomu; Inoue, Asuka; Tsuboi, Kazuhito; Jin, Xing-Hua; Araki, Nobukazu; Aoki, Junken; Arai, Hiroyuki; Ueda, Natsuo.

J Biol Chem ; 287(4): 2706-18, 2012 Jan 20.

Artigo em Inglês | MEDLINE | ID: mdl-22134920

14.

Generation of N-acylphosphatidylethanolamine by members of the phospholipase A/acyltransferase (PLA/AT) family.

Uyama, Toru; Ikematsu, Natsuki; Inoue, Manami; Shinohara, Naoki; Jin, Xing-Hua; Tsuboi, Kazuhito; Tonai, Takeharu; Tokumura, Akira; Ueda, Natsuo.

J Biol Chem ; 287(38): 31905-19, 2012 Sep 14.

Artigo em Inglês | MEDLINE | ID: mdl-22825852

15.

Assay of NAT Activity.

Uyama, Toru; Ueda, Natsuo.

Methods Mol Biol ; 2576: 213-224, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-36152189

16.

ß-1,4-Galactan suppresses lipid synthesis in sebaceous gland cells via TLR4.

Ayaki, Satomi; Mii, Tomohiro; Matsuno, Kosuke; Tokuyama, Takaaki; Tokuyama, Takahito; Tokuyama, Takashi; Uyama, Toru; Ueda, Natsuo.

J Biochem ; 173(2): 85-94, 2023 Feb 03.

Artigo em Inglês | MEDLINE | ID: mdl-36288613

17.

PLAAT1 expression triggers fragmentation of mitochondria in an enzyme activity-dependent manner.

Sikder, Mohammad Mamun; Uyama, Toru; Sasaki, Sumire; Kawai, Katsuhisa; Araki, Nobukazu; Ueda, Natsuo.

J Biochem ; 175(1): 101-113, 2023 Dec 20.

Artigo em Inglês | MEDLINE | ID: mdl-37818970

18.

Vasoactive intestinal peptide blockade suppresses tumor growth by regulating macrophage polarization and function in CT26 tumor-bearing mice.

Kittikulsuth, Wararat; Nakano, Daisuke; Kitada, Kento; Uyama, Toru; Ueda, Natsuo; Asano, Eisuke; Okano, Keiichi; Matsuda, Yoko; Nishiyama, Akira.

Sci Rep ; 13(1): 927, 2023 01 17.

Artigo em Inglês | MEDLINE | ID: mdl-36650220

19.

Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and -independent pathways.

Tsuboi, Kazuhito; Okamoto, Yasuo; Ikematsu, Natsuki; Inoue, Manami; Shimizu, Yoshibumi; Uyama, Toru; Wang, Jun; Deutsch, Dale G; Burns, Matthew P; Ulloa, Nadine M; Tokumura, Akira; Ueda, Natsuo.

Biochim Biophys Acta ; 1811(10): 565-77, 2011 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-21801852

20.

Heparanase-enhanced shedding of syndecan-1 by myeloma cells promotes endothelial invasion and angiogenesis.

Purushothaman, Anurag; Uyama, Toru; Kobayashi, Fumi; Yamada, Shuhei; Sugahara, Kazuyuki; Rapraeger, Alan C; Sanderson, Ralph D.

Blood ; 115(12): 2449-57, 2010 Mar 25.

Artigo em Inglês | MEDLINE | ID: mdl-20097882

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