Detalhe da pesquisa
1.
Exploring the Higher Order Structure and Conformational Transitions in Insulin Microcrystalline Biopharmaceuticals by Proton-Detected Solid-State Nuclear Magnetic Resonance at Natural Abundance.
Anal Chem
; 96(12): 4756-4763, 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38326990
2.
Mapping of Methyl Epitopes of a Peptide-Drug with Its Receptor by 2D STDD-Methyl TROSY NMR Spectroscopy.
Chembiochem
; 23(23): e202200489, 2022 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36227643
3.
Large scale purification and characterization of A21 deamidated variant-most prominent post translational modification (PTM) for insulins which is also widely observed in insulins pharmaceutical manufacturing and storage.
Protein Expr Purif
; 185: 105895, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33957255
4.
Monitoring Ras Interactions with the Nucleotide Exchange Factor Son of Sevenless (Sos) Using Site-specific NMR Reporter Signals and Intrinsic Fluorescence.
J Biol Chem
; 291(4): 1703-1718, 2016 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26565026
5.
Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors.
Nature
; 463(7280): 501-6, 2010 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20072125
6.
High-pressure NMR reveals close similarity between cold and alcohol protein denaturation in ubiquitin.
Proc Natl Acad Sci U S A
; 110(5): E368-76, 2013 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23284170
7.
Facile backbone structure determination of human membrane proteins by NMR spectroscopy.
Nat Methods
; 9(8): 834-9, 2012 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22609626
8.
Kinase in motion: insights into the dynamic nature of p38α by high-pressure NMR spectroscopic studies.
Chembiochem
; 14(14): 1799-806, 2013 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23843149
9.
Residual dipolar couplings measured in unfolded proteins are sensitive to amino-acid-specific geometries as well as local conformational sampling.
Biochem Soc Trans
; 40(5): 989-94, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22988852
10.
Simultaneous characterization of insulin HMWP and protamine sulphate in complex formulations through SEC-coupled mass spectrometry.
J Pharm Biomed Anal
; 203: 114188, 2021 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34126389
11.
Physicochemical and functional characterization of MYL-1501D, a proposed biosimilar to insulin glargine.
PLoS One
; 16(6): e0253168, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34133466
12.
Side-chain chi(1) conformations in urea-denatured ubiquitin and protein G from (3)J coupling constants and residual dipolar couplings.
J Am Chem Soc
; 132(9): 3196-203, 2010 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-20155903
13.
Dynamic studies of H-Rasâ¢GTPγS interactions with nucleotide exchange factor Sos reveal a transient ternary complex formation in solution.
Sci Rep
; 6: 29706, 2016 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27412770
14.
Structural and dynamic insights into the energetics of activation loop rearrangement in FGFR1 kinase.
Nat Commun
; 6: 7877, 2015 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26203596
15.
NMR backbone assignments of the tyrosine kinase domain of human fibroblast growth factor receptor 1.
Biomol NMR Assign
; 8(1): 85-8, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23325512
16.
Solution conformations and dynamics of ABL kinase-inhibitor complexes determined by NMR substantiate the different binding modes of imatinib/nilotinib and dasatinib.
J Biol Chem
; 283(26): 18292-302, 2008 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-18434310
17.
Backbone NMR resonance assignment of the Abelson kinase domain in complex with imatinib.
Biomol NMR Assign
; 2(1): 41-2, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19636920
18.
Residual dipolar couplings in short peptides reveal systematic conformational preferences of individual amino acids.
J Am Chem Soc
; 128(41): 13508-14, 2006 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-17031964