Detalhe da pesquisa
1.
Hepatic glutamine synthetase controls N5-methylglutamine in homeostasis and cancer.
Nat Chem Biol
; 19(3): 292-300, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36280791
2.
Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells.
EMBO Rep
; 24(10): e56279, 2023 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37489735
3.
Absent expansion of AXIN2+ hepatocytes and altered physiology in Axin2CreERT2 mice challenges the role of pericentral hepatocytes in homeostatic liver regeneration.
J Hepatol
; 78(5): 1028-1036, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36702176
4.
MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer.
Br J Cancer
; 122(6): 868-884, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31942031
5.
Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics.
Proc Natl Acad Sci U S A
; 112(11): 3475-80, 2015 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25733891
6.
Nucleoside-catabolizing enzymes in mycoplasma-infected tumor cell cultures compromise the cytostatic activity of the anticancer drug gemcitabine.
J Biol Chem
; 289(19): 13054-65, 2014 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-24668817
7.
Mycoplasma hyorhinis-encoded purine nucleoside phosphorylase: kinetic properties and its effect on the cytostatic potential of purine-based anticancer drugs.
Mol Pharmacol
; 84(6): 865-75, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24068428
8.
Role of human hypoxanthine guanine phosphoribosyltransferase in activation of the antiviral agent T-705 (favipiravir).
Mol Pharmacol
; 84(4): 615-29, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23907213
9.
Characterization of pyrimidine nucleoside phosphorylase of Mycoplasma hyorhinis: implications for the clinical efficacy of nucleoside analogues.
Biochem J
; 445(1): 113-23, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22475552
10.
Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target.
Nat Metab
; 5(8): 1303-1318, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37580540
11.
Cyclocreatine Suppresses Creatine Metabolism and Impairs Prostate Cancer Progression.
Cancer Res
; 82(14): 2565-2575, 2022 07 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35675421
12.
An emerging understanding of the Janus face of the human microbiome: enhancement versus impairment of cancer therapy.
J Antimicrob Chemother
; 69(10): 2878-80, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24925896
13.
Improving the metabolic fidelity of cancer models with a physiological cell culture medium.
Sci Adv
; 5(1): eaau7314, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30613774
14.
Increased formate overflow is a hallmark of oxidative cancer.
Nat Commun
; 9(1): 1368, 2018 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29636461
15.
Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation.
Cell Rep
; 18(3): 647-658, 2017 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28099844
16.
The metabolic fate of acetate in cancer.
Nat Rev Cancer
; 16(11): 708-717, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27562461
17.
The Nurture of Tumors Can Drive Their Metabolic Phenotype.
Cell Metab
; 23(3): 391-2, 2016 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-26959177
18.
Mycoplasma hyorhinis-encoded cytidine deaminase efficiently inactivates cytosine-based anticancer drugs.
FEBS Open Bio
; 5: 634-9, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26322268
19.
Mycoplasmas and cancer: focus on nucleoside metabolism.
EXCLI J
; 13: 300-22, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-26417262
20.
Microwave-assisted synthesis of C-8 aryl and heteroaryl inosines and determination of their inhibitory activities against Plasmodium falciparum purine nucleoside phosphorylase.
Eur J Med Chem
; 82: 459-65, 2014 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24929343