Detalhe da pesquisa
1.
Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis.
Cell
; 173(1): 260-274.e25, 2018 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29551266
2.
Bioaccumulation of therapeutic drugs by human gut bacteria.
Nature
; 597(7877): 533-538, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34497420
3.
Integrating metabolome dynamics and process data to guide cell line selection in biopharmaceutical process development.
Metab Eng
; 72: 353-364, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35429675
4.
An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in ex vivo human precision-cut lung slices.
Eur Respir J
; 58(1)2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33361096
5.
New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids.
Arch Toxicol
; 95(8): 2691-2718, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34151400
6.
New imidazoquinoxaline derivatives: Synthesis, biological evaluation on melanoma, effect on tubulin polymerization and structure-activity relationships.
Bioorg Med Chem
; 24(11): 2433-40, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27094151
7.
Metabolic rewiring revealed by cell-specific rate analyses from nontargeted exometabolomics during simultaneous consumption of glucose and lactic acid in a CHO fed-batch process.
J Biotechnol
; 359: 161-175, 2022 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36216209
8.
Exometabolome profiling reveals activation of the carnitine buffering pathway in fed-batch cultures of CHO cells co-fed with glucose and lactic acid.
Biotechnol Prog
; 37(6): e3198, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34328709
9.
Complementary NAD+ replacement strategies fail to functionally protect dystrophin-deficient muscle.
Skelet Muscle
; 10(1): 30, 2020 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33092650
10.
Identifying drug targets in tissues and whole blood with thermal-shift profiling.
Nat Biotechnol
; 38(3): 303-308, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31959954
11.
Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation.
Science
; 368(6489): 387-394, 2020 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32193360
12.
Click chemistry enables preclinical evaluation of targeted epigenetic therapies.
Science
; 356(6345): 1397-1401, 2017 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28619718
13.
A Modular Probe Strategy for Drug Localization, Target Identification and Target Occupancy Measurement on Single Cell Level.
ACS Chem Biol
; 11(9): 2541-50, 2016 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27384741
14.
Structural characterization of in vitro metabolites of the new anticancer agent EAPB0503 by liquid chromatography-tandem mass spectrometry.
J Pharm Biomed Anal
; 88: 429-40, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24176748