Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

The imprinted polycomb group gene Sfmbt2 is required for trophoblast maintenance and placenta development.

Miri, Kamelia; Latham, Keith; Panning, Barbara; Zhong, Zhisheng; Andersen, Angela; Varmuza, Susannah.

Development ; 140(22): 4480-9, 2013 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-24154523

2.

What does genetics tell us about imprinting and the placenta connection?

Varmuza, Susannah; Miri, Kamelia.

Cell Mol Life Sci ; 72(1): 51-72, 2015 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-25194419

3.

PPP1CC2 can form a kinase/phosphatase complex with the testis-specific proteins TSSK1 and TSKS in the mouse testis.

MacLeod, Graham; Shang, Peng; Booth, Gregory T; Mastropaolo, Lucas A; Manafpoursakha, Niloufar; Vogl, A Wayne; Varmuza, Susannah.

Reproduction ; 147(1): 1-12, 2014 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-24088291

4.

Tandem affinity purification in transgenic mouse embryonic stem cells identifies DDOST as a novel PPP1CC2 interacting protein.

MacLeod, Graham; Varmuza, Susannah.

Biochemistry ; 51(48): 9678-88, 2012 Dec 04.

Artigo em Inglês | MEDLINE | ID: mdl-23140390

5.

Recent acquisition of imprinting at the rodent Sfmbt2 locus correlates with insertion of a large block of miRNAs.

Wang, Qianwei; Chow, Jacqueline; Hong, Jenny; Smith, Anne Ferguson; Moreno, Carol; Seaby, Peter; Vrana, Paul; Miri, Kamelia; Tak, Joon; Chung, Eu Ddeum; Mastromonaco, Gabriela; Caniggia, Isabella; Varmuza, Susannah.

BMC Genomics ; 12: 204, 2011 Apr 21.

Artigo em Inglês | MEDLINE | ID: mdl-21510876

6.

Loss of protein phosphatase 1c{gamma} (PPP1CC) leads to impaired spermatogenesis associated with defects in chromatin condensation and acrosome development: an ultrastructural analysis.

Forgione, Nicole; Vogl, A Wayne; Varmuza, Susannah.

Reproduction ; 139(6): 1021-9, 2010 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-20385779

7.

Identification of potentially damaging amino acid substitutions leading to human male infertility.

Kuzmin, Anastasia; Jarvi, Keith; Lo, Kirk; Spencer, Leia; Chow, Gary Y C; Macleod, Graham; Wang, Qianwei; Varmuza, Susannah.

Biol Reprod ; 81(2): 319-26, 2009 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-19369647

8.

Unique trophoblast chromatin environment mediated by the PcG protein SFMBT2.

Tang, Priscilla; Miri, Kamelia; Varmuza, Susannah.

Biol Open ; 8(8)2019 Aug 23.

Artigo em Inglês | MEDLINE | ID: mdl-31391163

9.

The PcG gene Sfmbt2 is paternally expressed in extraembryonic tissues.

Kuzmin, Anastasia; Han, Zhiming; Golding, Michael C; Mann, Mellissa R W; Latham, Keith E; Varmuza, Susannah.

Gene Expr Patterns ; 8(2): 107-16, 2008 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-18024232

10.

Positive regulation of TRAF6-dependent innate immune responses by protein phosphatase PP1-Î³.

Opaluch, Amanda M; Schneider, Monika; Chiang, Chih-yuan; Nguyen, Quy T; Maestre, Ana M; Mulder, Lubbertus C F; Secundino, Ismael; De Jesus, Paul D; König, Renate; Simon, Viviana; Nizet, Victor; MacLeod, Graham; Varmuza, Susannah; Fernandez-Sesma, Ana; Chanda, Sumit K.

PLoS One ; 9(2): e89284, 2014.

Artigo em Inglês | MEDLINE | ID: mdl-24586659

11.

The application of proteomic approaches to the study of mammalian spermatogenesis and sperm function.

Macleod, Graham; Varmuza, Susannah.

FEBS J ; 280(22): 5635-51, 2013 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-23902417

12.

Imprinting and extraembryonic tissues-mom takes control.

Miri, Kamelia; Varmuza, Susannah.

Int Rev Cell Mol Biol ; 276: 215-62, 2009.

Artigo em Inglês | MEDLINE | ID: mdl-19584014

13.

Metakaryotic stem cell lineages in organogenesis of humans and other metazoans.

Gostjeva, Elena V; Koledova, Vera; Tomita-Mitchell, Aoy; Mitchell, Michael; Goetsch, Mary A; Varmuza, Susannah; Fomina, Janna N; Darroudi, Firouz; Thilly, William G.

Organogenesis ; 5(4): 191-200, 2009 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-20539738

14.

A testis specific isoform of endophilin B1, endophilin B1t, interacts specifically with protein phosphatase-1c gamma2 in mouse testis and is abnormally expressed in PP1c gamma null mice.

Hrabchak, Christopher; Henderson, Hannah; Varmuza, Susannah.

Biochemistry ; 46(15): 4635-44, 2007 Apr 17.

Artigo em Inglês | MEDLINE | ID: mdl-17381077

15.

Epigenetics and the renaissance of heresy.

Varmuza, Susannah.

Genome ; 46(6): 963-7; discussion 968-73, 2003 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-14663513

16.

Teratogenic effects of parthenogenetic cells from LTXBO mice, a strain which develops ovarian teratomas at high frequency.

Louise Varmuza, Susannah.

Rouxs Arch Dev Biol ; 201(3): 142-148, 1992 May.

Artigo em Inglês | MEDLINE | ID: mdl-28305580

17.

Development to blastocyst is impaired when intracytoplasmic sperm injection is performed with abnormal sperm from infertile mice harboring a mutation in the protein phosphatase 1cgamma gene.

Davies, Tyler; Varmuza, Susannah.

Biol Reprod ; 68(4): 1470-6, 2003 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-12606345

18.

Identification of the spermatogenic zip protein Spz1 as a putative protein phosphatase-1 (PP1) regulatory protein that specifically binds the PP1cgamma2 splice variant in mouse testis.

Hrabchak, Christopher; Varmuza, Susannah.

J Biol Chem ; 279(35): 37079-86, 2004 Aug 27.

Artigo em Inglês | MEDLINE | ID: mdl-15226296

19.

Increased recombination frequency showing evidence of loss of interference is associated with abnormal testicular histopathology.

Varmuza, Susannah; Ling, Ling.

Mol Reprod Dev ; 64(4): 499-506, 2003 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-12589662

20.

Protein phosphatase 1cgamma is required in germ cells in murine testis.

Oppedisano-Wells, Leandra; Varmuza, Susannah.

Mol Reprod Dev ; 65(2): 157-66, 2003 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-12704726

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