Detalhe da pesquisa
1.
The constitutive activity of melanocortin-4 receptors in cAMP pathway is allosterically modulated by zinc and copper ions.
J Neurochem
; 153(3): 346-361, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31792980
2.
Dynamics of ligand binding to GPCR: Residence time of melanocortins and its modulation.
Pharmacol Res
; 113(Pt B): 747-753, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27268144
3.
Budded baculoviruses as a tool for a homogeneous fluorescence anisotropy-based assay of ligand binding to G protein-coupled receptors: the case of melanocortin 4 receptors.
Biochim Biophys Acta
; 1838(1 Pt B): 372-81, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24095674
4.
Illuminating Neuropeptide Y Y4 Receptor Binding: Fluorescent Cyclic Peptides with Subnanomolar Binding Affinity as Novel Molecular Tools.
ACS Pharmacol Transl Sci
; 7(4): 1142-1168, 2024 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38633582
5.
Intracellular dynamics of the Sigma-1 receptor observed with super-resolution imaging microscopy.
PLoS One
; 17(5): e0268563, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35584184
6.
Live-cell microscopy or fluorescence anisotropy with budded baculoviruses-which way to go with measuring ligand binding to M4 muscarinic receptors?
Open Biol
; 12(6): 220019, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35674179
7.
Picomolar fluorescent probes for compound affinity determination to carbonic anhydrase IX expressed in live cancer cells.
Sci Rep
; 12(1): 17644, 2022 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36271018
8.
Fluorescence Anisotropy-Based Assay for Characterization of Ligand Binding Dynamics to GPCRs: The Case of Cy3B-Labeled Ligands Binding to MC4 Receptors in Budded Baculoviruses.
Methods Mol Biol
; 2268: 119-136, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34085265
9.
Budded baculoviruses as a receptor display system to quantify ligand binding with TIRF microscopy.
Nanoscale
; 13(4): 2436-2447, 2021 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33464268
10.
Fluorescence anisotropy assay for pharmacological characterization of ligand binding dynamics to melanocortin 4 receptors.
Anal Biochem
; 402(1): 32-9, 2010 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20302839
11.
Proteochemometric modeling reveals the interaction site for Trp9 modified alpha-MSH peptides in melanocortin receptors.
Proteins
; 67(3): 653-60, 2007 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17357163
12.
Characterization of ligand binding to melanocortin 4 receptors using fluorescent peptides with improved kinetic properties.
Eur J Pharmacol
; 799: 58-66, 2017 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28132916
13.
Kinetic evidence for tandemly arranged ligand binding sites in melanocortin 4 receptor complexes.
Neurochem Int
; 49(5): 533-42, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16764968
14.
N-alkylated dipeptide amides and related structures as imitations of the melanocortins' active core.
Peptides
; 26(10): 1997-2016, 2005 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15985308
15.
Co-operative regulation of ligand binding to melanocortin receptor subtypes: evidence for interacting binding sites.
Eur J Pharmacol
; 512(2-3): 85-95, 2005 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-15840392
16.
Homogeneous fluorescence anisotropy-based assay for characterization of ligand binding dynamics to GPCRs in budded baculoviruses: the case of Cy3B-NDP-α-MSH binding to MC4 receptors.
Methods Mol Biol
; 1272: 37-50, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25563175
17.
New substituted piperazines as ligands for melanocortin receptors. Correlation to the X-ray structure of "THIQ".
J Med Chem
; 47(18): 4613-26, 2004 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-15317471
18.
Application of fluorescence methods for characterization of ligand binding to G protein coupled receptors.
Springerplus
; 4(Suppl 1): L19, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-27386181
19.
Design and synthesis of a library of tertiary amides: evaluation as mimetics of the melanocortins' active core.
Bioorg Med Chem
; 15(17): 5787-810, 2007 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17618123
20.
Proteochemometric mapping of the interaction of organic compounds with melanocortin receptor subtypes.
Mol Pharmacol
; 67(1): 50-9, 2005 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-15470082