Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

From Amish farm dust to bacterial lysates: The long and winding road to protection from allergic disease.

Vercelli, Donata.

Semin Immunol ; 68: 101779, 2023 07.

Artigo em Inglês | MEDLINE | ID: mdl-37210851

2.

Immune modulation by rural exposures and allergy protection.

Xing, Yuhan; Tsang, Miranda Sin-Man; Yang, Zhaowei; Wang, Maggie Haitian; Pivniouk, Vadim; Leung, Agnes Sze-Yin; Leung, Ting-Fan; Roponen, Marjut; Schaub, Bianca; Vercelli, Donata; Wong, Chun-Kwok; Li, Jing; Wong, Gary Wing-Kin.

Pediatr Allergy Immunol ; 35(2): e14086, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-38351891

3.

Asthma-protective agents in dust from traditional farm environments.

Marques Dos Santos, Mauricius; Pivniouk, Vadim; Rankl, Bettina; Walker, Alesia; Pagani, Giulia; Hertkorn, Norbert; Schmitt-Kopplin, Philippe; Müller, Christoph; Bracher, Franz; Merl-Pham, Juliane; Hauck, Stefanie M; Schloter, Michael; Michael, Ashley N; Anderson, Dayna; Honeker, Linnea; Gozdz, Justyna; Pivniouk, Oksana; Ober, Carole; Holbreich, Mark; Martinez, Fernando D; Snyder, Shane A; von Mutius, Erika; Vercelli, Donata.

J Allergy Clin Immunol ; 152(3): 610-621, 2023 09.

Artigo em Inglês | MEDLINE | ID: mdl-37271318

4.

Airway administration of OM-85, a bacterial lysate, blocks experimental asthma by targeting dendritic cells and the epithelium/IL-33/ILC2 axis.

Pivniouk, Vadim; Gimenes-Junior, Joao A; Ezeh, Peace; Michael, Ashley; Pivniouk, Oksana; Hahn, Seongmin; VanLinden, Sydney R; Malone, Sean P; Abidov, Amir; Anderson, Dayna; Gozdz, Justyna; DeVries, Avery; Martinez, Fernando D; Pasquali, Christian; Vercelli, Donata.

J Allergy Clin Immunol ; 149(3): 943-956, 2022 03.

Artigo em Inglês | MEDLINE | ID: mdl-34560105

5.

The OM-85 bacterial lysate inhibits SARS-CoV-2 infection of epithelial cells by downregulating SARS-CoV-2 receptor expression.

Pivniouk, Vadim; Pivniouk, Oksana; DeVries, Avery; Uhrlaub, Jennifer L; Michael, Ashley; Pivniouk, Denis; VanLinden, Sydney R; Conway, Michelle Y; Hahn, Seongmin; Malone, Sean P; Ezeh, Peace; Churko, Jared M; Anderson, Dayna; Kraft, Monica; Nikolich-Zugich, Janko; Vercelli, Donata.

J Allergy Clin Immunol ; 149(3): 923-933.e6, 2022 03.

Artigo em Inglês | MEDLINE | ID: mdl-34902435

6.

The role of epigenetics in multi-generational transmission of asthma: An NIAID workshop report-based narrative review.

Wheatley, Lisa M; Holloway, John W; Svanes, Cecilie; Sears, Malcolm R; Breton, Carrie; Fedulov, Alexey V; Nilsson, Eric; Vercelli, Donata; Zhang, Hongmei; Togias, Alkis; Arshad, Syed Hasan.

Clin Exp Allergy ; 52(11): 1264-1275, 2022 11.

Artigo em Inglês | MEDLINE | ID: mdl-36073598

7.

Maternal prenatal immunity, neonatal trained immunity, and early airway microbiota shape childhood asthma development.

DeVries, Avery; McCauley, Kathryn; Fadrosh, Douglas; Fujimura, Kei E; Stern, Debra A; Lynch, Susan V; Vercelli, Donata.

Allergy ; 77(12): 3617-3628, 2022 12.

Artigo em Inglês | MEDLINE | ID: mdl-35841380

8.

Type 2 inflammation modulates ACE2 and TMPRSS2 in airway epithelial cells.

Kimura, Hiroki; Francisco, Dave; Conway, Michelle; Martinez, Fernando D; Vercelli, Donata; Polverino, Francesca; Billheimer, Dean; Kraft, Monica.

J Allergy Clin Immunol ; 146(1): 80-88.e8, 2020 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-32422146

9.

Epigenetic landscape links upper airway microbiota in infancy with allergic rhinitis at 6 years of age.

Morin, Andréanne; McKennan, Chris G; Pedersen, Casper-Emil T; Stokholm, Jakob; Chawes, Bo L; Malby Schoos, Ann-Marie; Naughton, Katherine A; Thorsen, Jonathan; Mortensen, Martin S; Vercelli, Donata; Trivedi, Urvish; Sørensen, Søren J; Bisgaard, Hans; Nicolae, Dan L; Bønnelykke, Klaus; Ober, Carole.

J Allergy Clin Immunol ; 146(6): 1358-1366, 2020 12.

Artigo em Inglês | MEDLINE | ID: mdl-32693091

10.

The role of innate immunity in asthma development and protection: Lessons from the environment.

Pivniouk, Vadim; Gimenes Junior, Joao Antonio; Honeker, Linnea K; Vercelli, Donata.

Clin Exp Allergy ; 50(3): 282-290, 2020 03.

Artigo em Inglês | MEDLINE | ID: mdl-31581343

11.

T-cell phenotypes are associated with serum IgE levels in Amish and Hutterite children.

Hrusch, Cara L; Stein, Michelle M; Gozdz, Justyna; Holbreich, Mark; von Mutius, Erika; Vercelli, Donata; Ober, Carole; Sperling, Anne I.

J Allergy Clin Immunol ; 144(5): 1391-1401.e10, 2019 11.

Artigo em Inglês | MEDLINE | ID: mdl-31401285

12.

Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children.

Stein, Michelle M; Hrusch, Cara L; Gozdz, Justyna; Igartua, Catherine; Pivniouk, Vadim; Murray, Sean E; Ledford, Julie G; Marques Dos Santos, Mauricius; Anderson, Rebecca L; Metwali, Nervana; Neilson, Julia W; Maier, Raina M; Gilbert, Jack A; Holbreich, Mark; Thorne, Peter S; Martinez, Fernando D; von Mutius, Erika; Vercelli, Donata; Ober, Carole; Sperling, Anne I.

N Engl J Med ; 375(5): 411-421, 2016 Aug 04.

Artigo em Inglês | MEDLINE | ID: mdl-27518660

13.

Interactions between host epigenetics and microbiota: Who does what to whom, when, and why?

Vercelli, Donata; Lynch, Susan V.

J Allergy Clin Immunol ; 151(6): 1465-1467, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-36720286

14.

Of pleiotropy and trajectories: Does the TGF-ß pathway link childhood asthma and chronic obstructive pulmonary disease?

DeVries, Avery; Vercelli, Donata.

J Allergy Clin Immunol ; 141(6): 1992-1996, 2018 06.

Artigo em Inglês | MEDLINE | ID: mdl-29709672

15.

Maternal Cytokine Profiles during Pregnancy Predict Asthma in Children of Mothers without Asthma.

Rothers, Janet; Stern, Debra A; Lohman, I Carla; Spangenberg, Amber; Wright, Anne L; DeVries, Avery; Vercelli, Donata; Halonen, Marilyn.

Am J Respir Cell Mol Biol ; 59(5): 592-600, 2018 11.

Artigo em Inglês | MEDLINE | ID: mdl-29863910

16.

The role of ST2 and ST2 genetic variants in schistosomiasis.

Long, Xin; Daya, Michelle; Zhao, Jianping; Rafaels, Nicholas; Liang, Huifang; Potee, Joseph; Campbell, Monica; Zhang, Bixiang; Araujo, Maria Ilma; Oliveira, Ricardo R; Mathias, Rasika A; Gao, Li; Ruczinski, Ingo; Georas, Steve N; Vercelli, Donata; Beaty, Terri H; Barnes, Kathleen C; Chen, Xiaoping; Chen, Qian.

J Allergy Clin Immunol ; 140(5): 1416-1422.e6, 2017 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-28189770

17.

Epigenome-wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothers.

DeVries, Avery; Wlasiuk, Gabriela; Miller, Susan J; Bosco, Anthony; Stern, Debra A; Lohman, I Carla; Rothers, Janet; Jones, Anya C; Nicodemus-Johnson, Jessie; Vasquez, Monica M; Curtin, John A; Simpson, Angela; Custovic, Adnan; Jackson, Daniel J; Gern, James E; Lemanske, Robert F; Guerra, Stefano; Wright, Anne L; Ober, Carole; Halonen, Marilyn; Vercelli, Donata.

J Allergy Clin Immunol ; 140(2): 534-542, 2017 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-28011059

18.

Microbiota, Epigenetics, and Trained Immunity. Convergent Drivers and Mediators of the Asthma Trajectory from Pregnancy to Childhood.

Lynch, Susan V; Vercelli, Donata.

Am J Respir Crit Care Med ; 203(7): 802-808, 2021 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-33493428

19.

Exploration of early-life candidate biomarkers for childhood asthma using antibody arrays.

Xu, Haili; Radabaugh, Timothy; Lu, Zhenqiang; Galligan, Michael; Billheimer, Dean; Vercelli, Donata; Wright, Anne L; Monks, Terrence J; Halonen, Marilyn; Lau, Serrine S.

Pediatr Allergy Immunol ; 27(7): 696-701, 2016 11.

Artigo em Inglês | MEDLINE | ID: mdl-27434124

20.

Does epigenetics play a role in human asthma?