Detalhe da pesquisa
1.
Rapid recruitment of p53 to DNA damage sites directs DNA repair choice and integrity.
Proc Natl Acad Sci U S A
; 119(10): e2113233119, 2022 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35235448
2.
Preclinical Assessment of the Combination of PSMA-Targeting Radionuclide Therapy with PARP Inhibitors for Prostate Cancer Treatment.
Int J Mol Sci
; 23(14)2022 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35887398
3.
C-Terminal Extensions of Ku70 and Ku80 Differentially Influence DNA End Binding Properties.
Int J Mol Sci
; 21(18)2020 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32937838
4.
XLF deficiency results in reduced N-nucleotide addition during V(D)J recombination.
Blood
; 128(5): 650-9, 2016 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27281794
5.
Tumor slice culture system to assess drug response of primary breast cancer.
BMC Cancer
; 16: 78, 2016 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26860465
6.
Functional Homologous Recombination (HR) Screening Shows the Majority of BRCA1/2-Mutant Breast and Ovarian Cancer Cell Lines Are HR-Proficient.
Cancers (Basel)
; 16(4)2024 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38398132
7.
MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response.
EMBO J
; 28(14): 2090-9, 2009 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-19536137
8.
DNA-PKcs inhibitors sensitize neuroendocrine tumor cells to peptide receptor radionuclide therapy in vitro and in vivo.
Theranostics
; 13(10): 3117-3130, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37351169
9.
In Vivo Efficacy Testing of Peptide Receptor Radionuclide Therapy Radiosensitization Using Olaparib.
Cancers (Basel)
; 15(3)2023 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36765883
10.
Proof-of-concept study linking ex vivo sensitivity testing to neoadjuvant anthracycline-based chemotherapy response in breast cancer patients.
NPJ Breast Cancer
; 9(1): 80, 2023 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37777518
11.
Ex Vivo Functional Assay for Evaluating Treatment Response in Tumor Tissue of Head and Neck Squamous Cell Carcinoma.
Cancers (Basel)
; 15(2)2023 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36672427
12.
A DNA-PKcs mutation in a radiosensitive T-B- SCID patient inhibits Artemis activation and nonhomologous end-joining.
J Clin Invest
; 119(1): 91-8, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19075392
13.
Functional Ex Vivo Tissue-Based Chemotherapy Sensitivity Testing for Breast Cancer.
Cancers (Basel)
; 14(5)2022 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35267560
14.
Functional RECAP (REpair CAPacity) assay identifies homologous recombination deficiency undetected by DNA-based BRCAness tests.
Oncogene
; 41(26): 3498-3506, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35662281
15.
Inter and intra-tumor somatostatin receptor 2 heterogeneity influences peptide receptor radionuclide therapy response.
Theranostics
; 11(2): 491-505, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33391488
16.
A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair.
Cancer Res
; 81(24): 6171-6182, 2021 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34548335
17.
A new type of radiosensitive T-B-NK+ severe combined immunodeficiency caused by a LIG4 mutation.
J Clin Invest
; 116(1): 137-45, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16357942
18.
Direct Ex Vivo Observation of Homologous Recombination Defect Reversal After DNA-Damaging Chemotherapy in Patients With Metastatic Breast Cancer.
JCO Precis Oncol
; 3: 1-12, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-35100677
19.
Functional Ex Vivo Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects.
Clin Cancer Res
; 24(24): 6277-6287, 2018 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30139880
20.
The role of DNA dependent protein kinase in synapsis of DNA ends.
Nucleic Acids Res
; 31(24): 7238-46, 2003 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-14654699