Detalhe da pesquisa
1.
Different Purkinje cell pathologies cause specific patterns of progressive gait ataxia in mice.
Neurobiol Dis
; 192: 106422, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38286390
2.
Base editor repairs mutation found in the premature-ageing syndrome progeria.
Nature
; 589(7843): 522-524, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33408358
3.
Genome Integrity in Aging: Human Syndromes, Mouse Models, and Therapeutic Options.
Annu Rev Pharmacol Toxicol
; 56: 427-45, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26514200
4.
Akkermansia muciniphila ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging Ercc1 -/Δ7 mice.
Immun Ageing
; 16: 6, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30899315
5.
Dietary restriction but not angiotensin II type 1 receptor blockade improves DNA damage-related vasodilator dysfunction in rapidly aging Ercc1Δ/- mice.
Clin Sci (Lond)
; 131(15): 1941-1953, 2017 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28620011
6.
Cell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiency.
PLoS Genet
; 10(10): e1004686, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25299392
7.
Spatio-temporal analysis of molecular determinants of neuronal degeneration in the aging mouse cerebellum.
Mol Cell Proteomics
; 12(5): 1350-62, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23399551
8.
Metabolomic analysis of dietary-restriction-induced attenuation of sarcopenia in prematurely aging DNA repair-deficient mice.
J Cachexia Sarcopenia Muscle
; 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38689513
9.
Hybrid Molecular and Functional Micro-CT Imaging Reveals Increased Myocardial Apoptosis Preceding Cardiac Failure in Progeroid Ercc1 Mice.
Mol Imaging Biol
; 2024 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38498063
10.
Gene expression changes in cerebellum induced by dietary restriction.
Front Mol Neurosci
; 16: 1185665, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37293544
11.
Decreased hepatic thyroid hormone signaling in systemic and liver-specific but not brain-specific accelerated aging due to DNA repair deficiency in mice.
Eur Thyroid J
; 12(6)2023 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37878415
12.
Proteomic identification of in vivo interactors reveals novel function of skin cornification proteins.
J Proteome Res
; 11(6): 3068-76, 2012 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22519520
13.
Chemotherapy Side-Effects: Not All DNA Damage Is Equal.
Cancers (Basel)
; 14(3)2022 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35158895
14.
Purkinje-cell-specific DNA repair-deficient mice reveal that dietary restriction protects neurons by cell-intrinsic preservation of genomic health.
Front Aging Neurosci
; 14: 1095801, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36760711
15.
A Sample Preparation Method for the Simultaneous Profiling of Signaling Lipids and Polar Metabolites in Small Quantities of Muscle Tissues from a Mouse Model for Sarcopenia.
Metabolites
; 12(8)2022 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36005613
16.
Different responses to DNA damage determine ageing differences between organs.
Aging Cell
; 21(4): e13562, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35246937
17.
Fasting Intervention for Children With Unilateral Renal Tumors to Reduce Toxicity.
Front Pediatr
; 10: 828615, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35155309
18.
Corrigendum: The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside.
Front Aging
; 3: 1086552, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36506463
19.
The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside.
Front Aging
; 3: 1005322, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36313181
20.
In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration.
Acta Neuropathol Commun
; 9(1): 94, 2021 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34020718