Detalhe da pesquisa
1.
HFIP in Organic Synthesis.
Chem Rev
; 122(15): 12544-12747, 2022 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35848353
2.
Yohimbine as a Starting Point to Access Diverse Natural Product-Like Agents with Re-programmed Activities against Cancer-Relevant GPCR Targets.
Bioorg Med Chem
; 28(14): 115546, 2020 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32616180
3.
Harnessing the Chemistry of the Indole Heterocycle to Drive Discoveries in Biology and Medicine.
Chembiochem
; 20(18): 2273-2297, 2019 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30609199
4.
Pertuzumab, trastuzumab, and standard anthracycline- and taxane-based chemotherapy for the neoadjuvant treatment of patients with HER2-positive localized breast cancer (BERENICE): a phase II, open-label, multicenter, multinational cardiac safety study.
Ann Oncol
; 29(3): 646-653, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29253081
5.
A Tryptoline Ring-Distortion Strategy Leads to Complex and Diverse Biologically Active Molecules from the Indole Alkaloid Yohimbine.
Chemistry
; 23(18): 4327-4335, 2017 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27900785
6.
Synthetically Tuning the 2-Position of Halogenated Quinolines: Optimizing Antibacterial and Biofilm Eradication Activities via Alkylation and Reductive Amination Pathways.
Chemistry
; 22(27): 9181-9, 2016 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27245927
7.
Discovery of quinoline small molecules with potent dispersal activity against methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis biofilms using a scaffold hopping strategy.
Bioorg Med Chem Lett
; 24(21): 5076-80, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25264073
8.
Rationale and design of a UK database for a rare cancer type: the GEM Registry for gastrointestinal stromal tumours.
Br J Cancer
; 109(6): 1403-7, 2013 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-23963143
9.
Modular Synthetic Routes to Fluorine-Containing Halogenated Phenazine and Acridine Agents That Induce Rapid Iron Starvation in Methicillin-Resistant Staphylococcus aureus Biofilms.
ACS Infect Dis
; 8(2): 280-295, 2022 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35089005
10.
Ring Distortion of Vincamine Leads to the Identification of Re-Engineered Antiplasmodial Agents.
ACS Omega
; 6(31): 20455-20470, 2021 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34395993
11.
Influence of pharmacogenetics on response and toxicity in breast cancer patients treated with doxorubicin and cyclophosphamide.
Br J Cancer
; 102(6): 1003-9, 2010 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20179710
12.
Mesenchymal chondrosarcoma of the orbit: an unusual site for a rare tumour.
Eur J Cancer Care (Engl)
; 19(4): 551-3, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19686354
13.
Re-Engineering of Yohimbine's Biological Activity through Ring Distortion: Identification and Structure-Activity Relationships of a New Class of Antiplasmodial Agents.
ACS Infect Dis
; 6(2): 159-167, 2020 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31913597
14.
Preventing Morphine-Seeking Behavior through the Re-Engineering of Vincamine's Biological Activity.
J Med Chem
; 63(10): 5119-5138, 2020 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31913038
15.
Chemotherapy for early-stage breast cancer: a brief history.
Br J Cancer
; 101 Suppl 1: S2-5, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19756003
16.
Management of cardiac health in trastuzumab-treated patients with breast cancer: updated United Kingdom National Cancer Research Institute recommendations for monitoring.
Br J Cancer
; 100(5): 684-92, 2009 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19259090
17.
Expert opinion on the use of anthracyclines in patients with advanced breast cancer at cardiac risk.
Ann Oncol
; 20(5): 816-27, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19153118
18.
Halogenated quinolines bearing polar functionality at the 2-position: Identification of new antibacterial agents with enhanced activity against Staphylococcus epidermidis.
Eur J Med Chem
; 155: 705-713, 2018 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29936357
19.
TEXAS (Taxotere EXperience with Anthracyclines Study) trial: mature results of activity/toxicity of docetaxel given with anthracyclines in a community setting, as first line therapy for MBC.
Cancer Chemother Pharmacol
; 59(3): 413-8, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17009036
20.
Safety and tolerability of subcutaneous trastuzumab for the adjuvant treatment of human epidermal growth factor receptor 2-positive early breast cancer: SafeHer phase III study's primary analysis of 2573 patients.
Eur J Cancer
; 82: 237-246, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28625777