Detalhe da pesquisa
1.
Bioluminescent RAPPID Sensors for the Single-Step Detection of Soluble Axl and Multiplex Analysis of Cell Surface Cancer Biomarkers.
Anal Chem
; 94(17): 6548-6556, 2022 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35438976
2.
Neutralizing nanobodies targeting diverse chemokines effectively inhibit chemokine function.
J Biol Chem
; 288(35): 25173-25182, 2013 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23836909
3.
Functional selectivity of adenosine A1 receptor ligands?
Purinergic Signal
; 9(1): 91-100, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23054444
4.
Preclinical anti-tumour activity of HexaBody-CD38, a next-generation CD38 antibody with superior complement-dependent cytotoxic activity.
EBioMedicine
; 93: 104663, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37379657
5.
Mechanistic and pharmacodynamic studies of DuoBody-CD3x5T4 in preclinical tumor models.
Life Sci Alliance
; 5(11)2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36271507
6.
DuoBody-CD40x4-1BB induces dendritic-cell maturation and enhances T-cell activation through conditional CD40 and 4-1BB agonist activity.
J Immunother Cancer
; 10(6)2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35688554
7.
An Fc-inert PD-L1×4-1BB bispecific antibody mediates potent anti-tumor immunity in mice by combining checkpoint inhibition and conditional 4-1BB co-stimulation.
Oncoimmunology
; 11(1): 2030135, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35186440
8.
Preclinical Characterization and Phase I Trial Results of a Bispecific Antibody Targeting PD-L1 and 4-1BB (GEN1046) in Patients with Advanced Refractory Solid Tumors.
Cancer Discov
; 12(5): 1248-1265, 2022 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35176764
9.
Functional selectivity of adenosine receptor ligands.
Purinergic Signal
; 7(2): 171-92, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21544511
10.
CXCR3 antagonists: quaternary ammonium salts equipped with biphenyl- and polycycloaliphatic-anchors.
Bioorg Med Chem
; 19(11): 3384-93, 2011 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21570852
11.
Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions.
Glia
; 58(12): 1465-76, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20648639
12.
Exploring a pocket for polycycloaliphatic groups in the CXCR3 receptor with the aid of a modular synthetic strategy.
Bioorg Med Chem Lett
; 19(8): 2252-7, 2009 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19299127
13.
Noncompetitive antagonism and inverse agonism as mechanism of action of nonpeptidergic antagonists at primate and rodent CXCR3 chemokine receptors.
J Pharmacol Exp Ther
; 325(2): 544-55, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18270317
14.
Identification and characterization of circulating variants of CXCL12 from human plasma: effects on chemotaxis and mobilization of hematopoietic stem and progenitor cells.
Stem Cells Dev
; 23(16): 1959-74, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24708339
15.
Agonist-dependent effects of mutations in the sphingosine-1-phosphate type 1 receptor.
Eur J Pharmacol
; 667(1-3): 105-12, 2011 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21663738
16.
Functionally biased modulation of A(3) adenosine receptor agonist efficacy and potency by imidazoquinolinamine allosteric enhancers.
Biochem Pharmacol
; 82(6): 658-68, 2011 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21718691
17.
Sphingosine-1-phosphate receptors: zooming in on ligand-induced intracellular trafficking and its functional implications.
Mol Cells
; 29(2): 99-104, 2010 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20127285
18.
Towards small-molecule CXCR3 ligands with clinical potential.
ChemMedChem
; 3(6): 861-72, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18442035
19.
Synthesis and structure-activity relationships of 3H-quinazolin-4-ones and 3H-pyrido[2,3-d]pyrimidin-4-ones as CXCR3 receptor antagonists.
Arch Pharm (Weinheim)
; 340(6): 281-91, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17562560
20.
Chemokine-directed trafficking of receptor stimulus to different g proteins: selective inducible and constitutive signaling by human herpesvirus 6-encoded chemokine receptor U51.
Mol Pharmacol
; 69(3): 888-98, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16332987