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1.
J Investig Allergol Clin Immunol ; 31(2): 120-131, 2021 Apr 20.
Artigo em Inglês | MEDLINE | ID: mdl-31833477

RESUMO

BACKGROUND AND OBJECTIVES: Allergology has been a recognized medical specialty in Spain, with fully defined aims and competencies for more than 4 decades. However, in recent years, its visibility seems to have decreased somewhat. Objectives: To identify which specific factors have contributed to the waning of the importance of the specialty and find tangible solutions to consolidate its place as a front-line medical specialty. MATERIAL AND METHODS: An online population survey comprising 60 items of interest was prepared. The degree of agreement and the level of satisfaction with each item were assessed, and implementable initiatives in the short, medium, and long terms were defined in order to provide solutions to the issues identified. RESULTS: The survey was completed by a total of 167 specialists with an average of 18 years' experience. Most were from public reference hospitals, and 29.3% were heads of department. The line of action for which a good degree of agreement was achieved was to promote the inclusion of an allergist in multidisciplinary teams. The priority lines of action were to improve undergraduate and graduate training in allergology and specialized nursing, to identify curricula in Spain, and to develop robust teaching projects. CONCLUSIONS: The results revealed a high degree of homogeneity between professionals. The basic pillars highlighted were as follows: quality training, knowledge, and research in immunotherapy; an innovative portfolio of services endorsed by clinical practice guidelines; and presence in multidisciplinary teams and relevant hospital committees.


Assuntos
Alergia e Imunologia/tendências , Escolha da Profissão , Hipersensibilidade/epidemiologia , Pesquisa Biomédica , Humanos , Comunicação Interdisciplinar , Medicina , Espanha/epidemiologia
2.
Arch Intern Med ; 152(5): 1089, 1992 May.
Artigo em Inglês | MEDLINE | ID: mdl-1580711
3.
Chemotherapy ; 35(6): 449-53, 1989.
Artigo em Inglês | MEDLINE | ID: mdl-2612233

RESUMO

Five cases (3.5%) of reversible cephapirin-induced neutropenia were observed in 132 patients receiving this antibiotic. The disorder was severe (agranulocytosis) in 3 cases. Simultaneous maculopapular rash was observed in all of them and in 4 cases fever occurred. All the cases observed were female (p not significant). Neutropenia developed only after administration of high doses of the antibiotic for a prolonged period of time. In contrast to another 127 patients treated with cephapirin who did not develop neutropenia, neutropenic patients had received a mean daily dose, total dose, mean daily dose per kilogram and total dose per kilogram of body weight significantly larger (p = 0.05, 0.02, 0.001 and 0.001, respectively). The duration of therapy was significantly longer in the neutropenic group (p = 0.001). Neutropenia did not occur below 90 g of total dose, but when this amount was exceeded, the incidence of the disorder reached 26.3% (p less than 0.001). We conclude that when this drug must be used either for long periods of time or at high doses, a hematologic vigilance is recommendable.


Assuntos
Agranulocitose/induzido quimicamente , Cefalosporinas/efeitos adversos , Cefapirina/efeitos adversos , Neutropenia/induzido quimicamente , Adulto , Idoso , Cefapirina/administração & dosagem , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Neutropenia/complicações , Estudos Retrospectivos , Fatores de Tempo
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