Detalhe da pesquisa
1.
Kinetic proofreading through the multi-step activation of the ZAP70 kinase underlies early T cell ligand discrimination.
Nat Immunol
; 23(9): 1355-1364, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36045187
2.
Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics.
Nat Immunol
; 20(11): 1530-1541, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31591574
3.
LymphoAtlas: a dynamic and integrated phosphoproteomic resource of TCR signaling in primary T cells reveals ITSN2 as a regulator of effector functions.
Mol Syst Biol
; 16(7): e9524, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32618424
4.
Co-recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR-induced ubiquitylation.
Mol Syst Biol
; 12(7): 876, 2016 07 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27474268
5.
Phenotypic model for early T-cell activation displaying sensitivity, specificity, and antagonism.
Proc Natl Acad Sci U S A
; 110(10): E888-97, 2013 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23431198
6.
Noninvasive inference of the molecular chemotactic response using bacterial trajectories.
Proc Natl Acad Sci U S A
; 109(5): 1802-7, 2012 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-22307649
7.
Mapping the SLP76 interactome in T cells lacking each of the GRB2-family adaptors reveals molecular plasticity of the TCR signaling pathway.
Front Immunol
; 14: 1139123, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37006259
8.
Systems-level conservation of the proximal TCR signaling network of mice and humans.
J Exp Med
; 219(2)2022 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35061003
9.
The T cell CD6 receptor operates a multitask signalosome with opposite functions in T cell activation.
J Exp Med
; 218(2)2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33125054
10.
Quantifying biomolecule diffusivity using an optimal Bayesian method.
Biophys J
; 98(4): 596-605, 2010 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20159156
11.
CD5, an Undercover Regulator of TCR Signaling.
Front Immunol
; 9: 2900, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30581443
12.
Opposing regulatory functions of the TIM3 (HAVCR2) signalosome in primary effector T cells as revealed by quantitative interactomics.
Cell Mol Immunol
; 18(6): 1581-1583, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33139903
13.
T Cells Integrate Local and Global Cues to Discriminate between Structurally Similar Antigens.
Cell Rep
; 11(8): 1208-19, 2015 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26004178
14.
T cells translate individual, quantal activation into collective, analog cytokine responses via time-integrated feedbacks.
Elife
; 3: e01944, 2014 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-24719192
15.
Diversity training for signal transduction: leveraging cell-to-cell variability to dissect cellular signaling, differentiation and death.
Curr Opin Biotechnol
; 24(4): 760-6, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23747193
16.
Cell-to-cell variability analysis dissects the plasticity of signaling of common γ chain cytokines in T cells.
Sci Signal
; 6(266): ra17, 2013 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23482665
17.
Annular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse.
J Exp Med
; 210(12): 2721-37, 2013 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24190432
18.
Correction: Annular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse.
J Exp Med
; 214(4): 1203, 2017 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28292823