Detalhe da pesquisa
1.
CDK7-dependent transcriptional addiction in triple-negative breast cancer.
Cell
; 163(1): 174-86, 2015 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26406377
2.
PI3Kß controls immune evasion in PTEN-deficient breast tumours.
Nature
; 617(7959): 139-146, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37076617
3.
PIK3CA C-terminal frameshift mutations are novel oncogenic events that sensitize tumors to PI3K-α inhibition.
Proc Natl Acad Sci U S A
; 117(39): 24427-24433, 2020 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32929011
4.
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation.
Proc Natl Acad Sci U S A
; 115(41): E9600-E9609, 2018 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30254159
5.
Spatially distinct roles of class Ia PI3K isoforms in the development and maintenance of PTEN hamartoma tumor syndrome.
Genes Dev
; 27(14): 1568-80, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23873941
6.
PI3K isoform dependence of PTEN-deficient tumors can be altered by the genetic context.
Proc Natl Acad Sci U S A
; 111(17): 6395-400, 2014 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-24737887
7.
Blocking PI3K p110ß Attenuates Development of PTEN-Deficient Castration-Resistant Prostate Cancer.
Mol Cancer Res
; 20(5): 673-685, 2022 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35105671
8.
NTRK2 activation cooperates with PTEN deficiency in T-ALL through activation of both the PI3K-AKT and JAK-STAT3 pathways.
Cell Discov
; 2: 16030, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27672444
9.
A PI3K p110ß-Rac signalling loop mediates Pten-loss-induced perturbation of haematopoiesis and leukaemogenesis.
Nat Commun
; 6: 8501, 2015 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26442967
10.
Hematopoiesis and RAS-driven myeloid leukemia differentially require PI3K isoform p110α.
J Clin Invest
; 124(4): 1794-809, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24569456
11.
MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells.
Elife
; 3: e01763, 2014 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24844244
12.
Correction: MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells.
Elife
; 72018 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29528283
13.
Functional characterization of an isoform-selective inhibitor of PI3K-p110ß as a potential anticancer agent.
Cancer Discov
; 2(5): 425-33, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22588880