Detalhe da pesquisa
1.
Increased glucose metabolism and impaired glutamate transport in human astrocytes are potential early triggers of abnormal extracellular glutamate accumulation in hiPSC-derived models of Alzheimer's disease.
J Neurochem
; 2023 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38063257
2.
Proteomic phenotype of cerebral organoids derived from autism spectrum disorder patients reveal disrupted energy metabolism, cellular components, and biological processes.
Mol Psychiatry
; 27(9): 3749-3759, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35618886
3.
Staphylococcus aureus induces cell-surface expression of immune stimulatory NKG2D ligands on human monocytes.
J Biol Chem
; 295(33): 11803-11821, 2020 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32605922
4.
Clearance of activity-evoked K+ transients and associated glia cell swelling occur independently of AQP4: A study with an isoform-selective AQP4 inhibitor.
Glia
; 69(1): 28-41, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32506554
5.
Pharmacological inhibition of mitochondrial soluble adenylyl cyclase in astrocytes causes activation of AMP-activated protein kinase and induces breakdown of glycogen.
Glia
; 69(12): 2828-2844, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34378239
6.
Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease.
Neurobiol Dis
; 148: 105198, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33242587
7.
Two Metabolic Fuels, Glucose and Lactate, Differentially Modulate Exocytotic Glutamate Release from Cultured Astrocytes.
Neurochem Res
; 46(10): 2551-2579, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34057673
8.
Downregulation of GABA Transporter 3 (GAT3) is Associated with Deficient Oxidative GABA Metabolism in Human Induced Pluripotent Stem Cell-Derived Astrocytes in Alzheimer's Disease.
Neurochem Res
; 46(10): 2676-2686, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-33710537
9.
Deletion of Neuronal GLT-1 in Mice Reveals Its Role in Synaptic Glutamate Homeostasis and Mitochondrial Function.
J Neurosci
; 39(25): 4847-4863, 2019 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30926746
10.
AMP-activated protein kinase (AMPK) regulates astrocyte oxidative metabolism by balancing TCA cycle dynamics.
Glia
; 68(9): 1824-1839, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32092215
11.
Extensive astrocyte metabolism of γ-aminobutyric acid (GABA) sustains glutamine synthesis in the mammalian cerebral cortex.
Glia
; 68(12): 2601-2612, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32584476
12.
Conditional Knockout of GLT-1 in Neurons Leads to Alterations in Aspartate Homeostasis and Synaptic Mitochondrial Metabolism in Striatum and Hippocampus.
Neurochem Res
; 45(6): 1420-1437, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-32144526
13.
The role of astrocytes in seizure generation: insights from a novel in vitro seizure model based on mitochondrial dysfunction.
Brain
; 142(2): 391-411, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30689758
14.
Enhanced cerebral branched-chain amino acid metabolism in R6/2 mouse model of Huntington's disease.
Cell Mol Life Sci
; 76(12): 2449-2461, 2019 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-30830240
15.
Astrocytic glycogen metabolism in the healthy and diseased brain.
J Biol Chem
; 293(19): 7108-7116, 2018 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29572349
16.
Astrocytic pyruvate carboxylation: Status after 35 years.
J Neurosci Res
; 97(8): 890-896, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30801795
17.
Distinct differences in rates of oxygen consumption and ATP synthesis of regionally isolated non-synaptic mouse brain mitochondria.
J Neurosci Res
; 97(8): 961-974, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30675904
18.
Glycogen metabolism is impaired in the brain of male type 2 diabetic Goto-Kakizaki rats.
J Neurosci Res
; 97(8): 1004-1017, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31044444
19.
Expression of the human isoform of glutamate dehydrogenase, hGDH2, augments TCA cycle capacity and oxidative metabolism of glutamate during glucose deprivation in astrocytes.
Glia
; 65(3): 474-488, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28032919
20.
The antidiabetic drug metformin decreases mitochondrial respiration and tricarboxylic acid cycle activity in cultured primary rat astrocytes.
J Neurosci Res
; 95(11): 2307-2320, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28316081