Detalhe da pesquisa
1.
Dolutegravir Monotherapy of Simian Immunodeficiency Virus-Infected Macaques Selects for Several Patterns of Resistance Mutations with Variable Virological Outcomes.
J Virol
; 93(2)2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30381490
2.
The S230R Integrase Substitution Associated With Virus Load Rebound During Dolutegravir Monotherapy Confers Low-Level Resistance to Integrase Strand-Transfer Inhibitors.
J Infect Dis
; 218(5): 698-706, 2018 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29617824
3.
On-Demand Preexposure Prophylaxis in Men at High Risk for HIV-1 Infection.
N Engl J Med
; 373(23): 2237-46, 2015 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26624850
4.
Dolutegravir reshapes the genetic diversity of HIV-1 reservoirs.
J Antimicrob Chemother
; 73(4): 1045-1053, 2018 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29244129
5.
JAK-STAT Signaling Pathways and Inhibitors Affect Reversion of Envelope-Mutated HIV-1.
J Virol
; 91(9)2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28202754
6.
HIV-1 Resistance to Dolutegravir Is Affected by Cellular Histone Acetyltransferase Activity.
J Virol
; 91(21)2017 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28835492
7.
The antimalarial drug amodiaquine possesses anti-ZIKA virus activities.
J Med Virol
; 90(5): 796-802, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29315671
8.
HIV drug resistance against strand transfer integrase inhibitors.
Retrovirology
; 14(1): 36, 2017 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28583191
9.
Reduced antiretroviral drug efficacy and concentration in HIV-infected microglia contributes to viral persistence in brain.
Retrovirology
; 14(1): 47, 2017 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29037245
10.
Antiviral Activity of Bictegravir and Cabotegravir against Integrase Inhibitor-Resistant SIVmac239 and HIV-1.
Antimicrob Agents Chemother
; 61(12)2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28923862
11.
M184I/V substitutions and E138K/M184I/V double substitutions in HIV reverse transcriptase do not significantly affect the antiviral activity of EFdA.
J Antimicrob Chemother
; 72(11): 3008-3011, 2017 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28961903
12.
Monotherapy with either dolutegravir or raltegravir fails to durably suppress HIV viraemia in humanized mice.
J Antimicrob Chemother
; 72(9): 2570-2573, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28637235
13.
HIV-1 strains belonging to large phylogenetic clusters show accelerated escape from integrase inhibitors in cell culture compared with viral isolates from singleton/small clusters.
J Antimicrob Chemother
; 72(8): 2171-2183, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28472323
14.
Purification of Zika virus RNA-dependent RNA polymerase and its use to identify small-molecule Zika inhibitors.
J Antimicrob Chemother
; 72(3): 727-734, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28069884
15.
Identification of resveratrol analogs as potent anti-dengue agents using a cell-based assay.
J Med Virol
; 89(3): 397-407, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27509184
16.
Does antiretroviral treatment change HIV-1 codon usage patterns in its genes: a preliminary bioinformatics study.
AIDS Res Ther
; 14(1): 2, 2017 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28086981
17.
Effect on HIV-1 viral replication capacity of DTG-resistance mutations in NRTI/NNRTI resistant viruses.
Retrovirology
; 13(1): 31, 2016 04 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27130466
18.
Identification of a Pyridoxine-Derived Small-Molecule Inhibitor Targeting Dengue Virus RNA-Dependent RNA Polymerase.
Antimicrob Agents Chemother
; 60(1): 600-8, 2016 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26574011
19.
Polymorphic substitution E157Q in HIV-1 integrase increases R263K-mediated dolutegravir resistance and decreases DNA binding activity.
J Antimicrob Chemother
; 71(8): 2083-8, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27084918
20.
Development of a G118R mutation in HIV-1 integrase following a switch to dolutegravir monotherapy leading to cross-resistance to integrase inhibitors.
J Antimicrob Chemother
; 71(7): 1948-53, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27029845