Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

C13orf31 (FAMIN) is a central regulator of immunometabolic function.

Cader, M Zaeem; Boroviak, Katharina; Zhang, Qifeng; Assadi, Ghazaleh; Kempster, Sarah L; Sewell, Gavin W; Saveljeva, Svetlana; Ashcroft, Jonathan W; Clare, Simon; Mukhopadhyay, Subhankar; Brown, Karen P; Tschurtschenthaler, Markus; Raine, Tim; Doe, Brendan; Chilvers, Edwin R; Griffin, Jules L; Kaneider, Nicole C; Floto, R Andres; D'Amato, Mauro; Bradley, Allan; Wakelam, Michael J O; Dougan, Gordon; Kaser, Arthur.

Nat Immunol ; 17(9): 1046-56, 2016 09.

Artigo em Inglês | MEDLINE | ID: mdl-27478939

2.

Neuronal HSF-1 coordinates the propagation of fat desaturation across tissues to enable adaptation to high temperatures in C. elegans.

Chauve, Laetitia; Hodge, Francesca; Murdoch, Sharlene; Masoudzadeh, Fatemeh; Mann, Harry-Jack; Lopez-Clavijo, Andrea F; Okkenhaug, Hanneke; West, Greg; Sousa, Bebiana C; Segonds-Pichon, Anne; Li, Cheryl; Wingett, Steven W; Kienberger, Hermine; Kleigrewe, Karin; de Bono, Mario; Wakelam, Michael J O; Casanueva, Olivia.

PLoS Biol ; 19(11): e3001431, 2021 11.

Artigo em Inglês | MEDLINE | ID: mdl-34723964

3.

SnapShot: Lipid kinase and phosphatase reaction pathways.

Rudge, Simon A; Wakelam, Michael J O.

Cell ; 156(1-2): 376-376.e1, 2014 Jan 16.

Artigo em Inglês | MEDLINE | ID: mdl-24439389

4.

Comprehensive lipidome of human plasma using minimal sample manipulation by liquid chromatography coupled with mass spectrometry.

Sousa, Bebiana C; Klein, Zulema Gonzalez; Taylor, Diane; West, Greg; Huipeng, Aveline Neo; Wakelam, Michael J O; Lopez-Clavijo, Andrea F.

Rapid Commun Mass Spectrom ; : e9472, 2023 Jan 18.

Artigo em Inglês | MEDLINE | ID: mdl-36652341

5.

SnapShot: lipid kinases and phosphatases.

Rudge, Simon A; Wakelam, Michael J O.

Cell ; 155(7): 1654-1654.e1, 2013 Dec 19.

Artigo em Inglês | MEDLINE | ID: mdl-24360283

6.

Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures.

Liebisch, Gerhard; Fahy, Eoin; Aoki, Junken; Dennis, Edward A; Durand, Thierry; Ejsing, Christer S; Fedorova, Maria; Feussner, Ivo; Griffiths, William J; Köfeler, Harald; Merrill, Alfred H; Murphy, Robert C; O'Donnell, Valerie B; Oskolkova, Olga; Subramaniam, Shankar; Wakelam, Michael J O; Spener, Friedrich.

J Lipid Res ; 61(12): 1539-1555, 2020 12.

Artigo em Inglês | MEDLINE | ID: mdl-33037133

7.

MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer.

Casciano, Jessica C; Perry, Caroline; Cohen-Nowak, Adam J; Miller, Katelyn D; Vande Voorde, Johan; Zhang, Qifeng; Chalmers, Susan; Sandison, Mairi E; Liu, Qin; Hedley, Ann; McBryan, Tony; Tang, Hsin-Yao; Gorman, Nicole; Beer, Thomas; Speicher, David W; Adams, Peter D; Liu, Xuefeng; Schlegel, Richard; McCarron, John G; Wakelam, Michael J O; Gottlieb, Eyal; Kossenkov, Andrew V; Schug, Zachary T.

Br J Cancer ; 122(6): 868-884, 2020 03.

Artigo em Inglês | MEDLINE | ID: mdl-31942031

8.

CD151 regulates expression of FGFR2 in breast cancer cells via PKC-dependent pathways.

Sadej, Rafal; Lu, Xiaohong; Turczyk, Lukasz; Novitskaya, Vera; Lopez-Clavijo, Andrea F; Kordek, Radzislaw; Potemski, Piotr; Wakelam, Michael J O; Romanska-Knight, Hanna; Berditchevski, Fedor.

J Cell Sci ; 131(21)2018 10 29.

Artigo em Inglês | MEDLINE | ID: mdl-30257985

9.

Deciphering lipid structures based on platform-independent decision rules.

Hartler, Jürgen; Triebl, Alexander; Ziegl, Andreas; Trötzmüller, Martin; Rechberger, Gerald N; Zeleznik, Oana A; Zierler, Kathrin A; Torta, Federico; Cazenave-Gassiot, Amaury; Wenk, Markus R; Fauland, Alexander; Wheelock, Craig E; Armando, Aaron M; Quehenberger, Oswald; Zhang, Qifeng; Wakelam, Michael J O; Haemmerle, Guenter; Spener, Friedrich; Köfeler, Harald C; Thallinger, Gerhard G.

Nat Methods ; 14(12): 1171-1174, 2017 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-29058722

10.

Extracellular vesicles: lipids as key components of their biogenesis and functions.

Record, Michel; Silvente-Poirot, Sandrine; Poirot, Marc; Wakelam, Michael J O.

J Lipid Res ; 59(8): 1316-1324, 2018 08.

Artigo em Inglês | MEDLINE | ID: mdl-29764923

11.

Host lipidome analysis during rhinovirus replication in HBECs identifies potential therapeutic targets.

Nguyen, An; Guedán, Anabel; Mousnier, Aurelie; Swieboda, Dawid; Zhang, Qifeng; Horkai, Dorottya; Le Novere, Nicolas; Solari, Roberto; Wakelam, Michael J O.

J Lipid Res ; 59(9): 1671-1684, 2018 09.

Artigo em Inglês | MEDLINE | ID: mdl-29946055

12.

MS-based lipidomics of human blood plasma: a community-initiated position paper to develop accepted guidelines.

Burla, Bo; Arita, Makoto; Arita, Masanori; Bendt, Anne K; Cazenave-Gassiot, Amaury; Dennis, Edward A; Ekroos, Kim; Han, Xianlin; Ikeda, Kazutaka; Liebisch, Gerhard; Lin, Michelle K; Loh, Tze Ping; Meikle, Peter J; Oresic, Matej; Quehenberger, Oswald; Shevchenko, Andrej; Torta, Federico; Wakelam, Michael J O; Wheelock, Craig E; Wenk, Markus R.

J Lipid Res ; 59(10): 2001-2017, 2018 10.

Artigo em Inglês | MEDLINE | ID: mdl-30115755

13.

Exosomes bind to autotaxin and act as a physiological delivery mechanism to stimulate LPA receptor signalling in cells.

Jethwa, Susanna A; Leah, Emma J; Zhang, Qifeng; Bright, Nicholas A; Oxley, David; Bootman, Martin D; Rudge, Simon A; Wakelam, Michael J O.

J Cell Sci ; 129(20): 3948-3957, 2016 10 15.

Artigo em Inglês | MEDLINE | ID: mdl-27557622

14.

Autotaxin-lysophosphatidic acid receptor signalling regulates hepatitis C virus replication.

Farquhar, Michelle J; Humphreys, Isla S; Rudge, Simon A; Wilson, Garrick K; Bhattacharya, Bishnupriya; Ciaccia, Maria; Hu, Ke; Zhang, Qifeng; Mailly, Laurent; Reynolds, Gary M; Ashcroft, Margaret; Balfe, Peter; Baumert, Thomas F; Roessler, Stephanie; Wakelam, Michael J O; McKeating, Jane A.

J Hepatol ; 66(5): 919-929, 2017 05.

Artigo em Inglês | MEDLINE | ID: mdl-28126468

15.

Melanoma cells break down LPA to establish local gradients that drive chemotactic dispersal.

Muinonen-Martin, Andrew J; Susanto, Olivia; Zhang, Qifeng; Smethurst, Elizabeth; Faller, William J; Veltman, Douwe M; Kalna, Gabriela; Lindsay, Colin; Bennett, Dorothy C; Sansom, Owen J; Herd, Robert; Jones, Robert; Machesky, Laura M; Wakelam, Michael J O; Knecht, David A; Insall, Robert H.

PLoS Biol ; 12(10): e1001966, 2014 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-25313567

16.

Speed and sensitivity of phototransduction in Drosophila depend on degree of saturation of membrane phospholipids.

Randall, Alex S; Liu, Che-Hsiung; Chu, Brian; Zhang, Qifeng; Dongre, Sidharta A; Juusola, Mikko; Franze, Kristian; Wakelam, Michael J O; Hardie, Roger C.

J Neurosci ; 35(6): 2731-46, 2015 Feb 11.

Artigo em Inglês | MEDLINE | ID: mdl-25673862

17.

Phosphatidylinositolphosphate phosphatase activities and cancer.

Rudge, Simon A; Wakelam, Michael J O.

J Lipid Res ; 57(2): 176-92, 2016 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-26302980

18.

Phosphoinositide 3-kinase-related overgrowth: cellular phenotype and future therapeutic options.

Parker, Victoria E R; Knox, Rachel G; Zhang, Qifeng; Wakelam, Michael J O; Semple, Robert K.

Lancet ; 385 Suppl 1: S77, 2015 Feb 26.

Artigo em Inglês | MEDLINE | ID: mdl-26312899

19.

Lipid droplet formation in response to oleic acid in Huh-7 cells is mediated by the fatty acid receptor FFAR4.

Rohwedder, Arndt; Zhang, Qifeng; Rudge, Simon A; Wakelam, Michael J O.

J Cell Sci ; 127(Pt 14): 3104-15, 2014 Jul 15.

Artigo em Inglês | MEDLINE | ID: mdl-24876224

20.

The proto-oncogene PBF binds p53 and is associated with prognostic features in colorectal cancer.

Read, Martin L; Seed, Robert I; Modasia, Bhavika; Kwan, Perkin P K; Sharma, Neil; Smith, Vicki E; Watkins, Rachel J; Bansal, Sukhchain; Gagliano, Teresa; Stratford, Anna L; Ismail, Tariq; Wakelam, Michael J O; Kim, Dae S; Ward, Stephen T; Boelaert, Kristien; Franklyn, Jayne A; Turnell, Andrew S; McCabe, Christopher J.

Mol Carcinog ; 55(1): 15-26, 2016 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-25408419

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C13orf31 (FAMIN) is a central regulator of immunometabolic function.

Neuronal HSF-1 coordinates the propagation of fat desaturation across tissues to enable adaptation to high temperatures in C. elegans.

SnapShot: Lipid kinase and phosphatase reaction pathways.

Comprehensive lipidome of human plasma using minimal sample manipulation by liquid chromatography coupled with mass spectrometry.

SnapShot: lipid kinases and phosphatases.

Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures.

MYC regulates fatty acid metabolism through a multigenic program in claudin-low triple negative breast cancer.

CD151 regulates expression of FGFR2 in breast cancer cells via PKC-dependent pathways.

Deciphering lipid structures based on platform-independent decision rules.

Extracellular vesicles: lipids as key components of their biogenesis and functions.

Host lipidome analysis during rhinovirus replication in HBECs identifies potential therapeutic targets.

MS-based lipidomics of human blood plasma: a community-initiated position paper to develop accepted guidelines.

Exosomes bind to autotaxin and act as a physiological delivery mechanism to stimulate LPA receptor signalling in cells.

Autotaxin-lysophosphatidic acid receptor signalling regulates hepatitis C virus replication.

Melanoma cells break down LPA to establish local gradients that drive chemotactic dispersal.

Speed and sensitivity of phototransduction in Drosophila depend on degree of saturation of membrane phospholipids.

Phosphatidylinositolphosphate phosphatase activities and cancer.

Phosphoinositide 3-kinase-related overgrowth: cellular phenotype and future therapeutic options.

Lipid droplet formation in response to oleic acid in Huh-7 cells is mediated by the fatty acid receptor FFAR4.

The proto-oncogene PBF binds p53 and is associated with prognostic features in colorectal cancer.