Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function.

Lo, Wan-Lin; Kuhlmann, Miriam; Rizzuto, Gabrielle; Ekiz, H Atakan; Kolawole, Elizabeth M; Revelo, Monica P; Andargachew, Rakieb; Li, Zhongmei; Tsai, Yuan-Li; Marson, Alexander; Evavold, Brian D; Zehn, Dietmar; Weiss, Arthur.

Nat Immunol ; 24(4): 676-689, 2023 04.

Artigo em Inglês | MEDLINE | ID: mdl-36914891

2.

Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination.

Lo, Wan-Lin; Shah, Neel H; Rubin, Sara A; Zhang, Weiguo; Horkova, Veronika; Fallahee, Ian R; Stepanek, Ondrej; Zon, Leonard I; Kuriyan, John; Weiss, Arthur.

Nat Immunol ; 20(11): 1481-1493, 2019 11.

Artigo em Inglês | MEDLINE | ID: mdl-31611699

3.

Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT.

Lo, Wan-Lin; Shah, Neel H; Ahsan, Nagib; Horkova, Veronika; Stepanek, Ondrej; Salomon, Arthur R; Kuriyan, John; Weiss, Arthur.

Nat Immunol ; 19(7): 733-741, 2018 07.

Artigo em Inglês | MEDLINE | ID: mdl-29915297

4.

Two CTLA-4 ligands, separate pHates.

Humphries, Preston A; Lo, Wan-Lin.

Nat Immunol ; 23(9): 1297-1299, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-35999395

5.

A multi-view graph contrastive learning framework for deciphering spatially resolved transcriptomics data.

Zhang, Lei; Liang, Shu; Wan, Lin.

Brief Bioinform ; 25(4)2024 May 23.

Artigo em Inglês | MEDLINE | ID: mdl-38801701

6.

Intrinsic CD4+ T cell sensitivity and response to a pathogen are set and sustained by avidity for thymic and peripheral complexes of self peptide and MHC.

Persaud, Stephen P; Parker, Chelsea R; Lo, Wan-Lin; Weber, K Scott; Allen, Paul M.

Nat Immunol ; 15(3): 266-74, 2014 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-24487322

7.

Author Correction: The Apostasia genome and the evolution of orchids.

Zhang, Guo-Qiang; Liu, Ke-Wei; Li, Zhen; Lohaus, Rolf; Hsiao, Yu-Yun; Niu, Shan-Ce; Wang, Jie-Yu; Lin, Yao-Cheng; Xu, Qing; Chen, Li-Jun; Yoshida, Kouki; Fujiwara, Sumire; Wang, Zhi-Wen; Zhang, Yong-Qiang; Mitsuda, Nobutaka; Wang, Meina; Liu, Guo-Hui; Pecoraro, Lorenzo; Huang, Hui-Xia; Xiao, Xin-Ju; Lin, Min; Wu, Xin-Yi; Wu, Wan-Lin; Chen, You-Yi; Chang, Song-Bin; Sakamoto, Shingo; Ohme-Takagi, Masaru; Yagi, Masafumi; Zeng, Si-Jin; Shen, Ching-Yu; Yeh, Chuan-Ming; Luo, Yi-Bo; Tsai, Wen-Chieh; Van de Peer, Yves; Liu, Zhong-Jian.

Nature ; 583(7818): E30, 2020 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-32681116

8.

ZAP70, too little, too much can lead to autoimmunity.

Ashouri, Judith F; Lo, Wan-Lin; Nguyen, Trang T T; Shen, Lin; Weiss, Arthur.

Immunol Rev ; 307(1): 145-160, 2022 05.

Artigo em Inglês | MEDLINE | ID: mdl-34923645

9.

Divergent electroencephalogram resting-state functional network alterations in subgroups of autism spectrum disorder: a symptom-based clustering analysis.

Zhu, Gang; Li, Yuhang; Wan, Lin; Sun, Chunhua; Liu, Xinting; Zhang, Jing; Liang, Yan; Liu, Guoyin; Yan, Huimin; Li, Rihui; Yang, Guang.

Cereb Cortex ; 34(1)2024 01 14.

Artigo em Inglês | MEDLINE | ID: mdl-37950877

10.

Rethinking therapeutic strategies of dual-target drugs: An update on pharmacological small-molecule compounds in cancer.

Yang, Yiren; Mou, Yi; Wan, Lin-Xi; Zhu, Shiou; Wang, Guan; Gao, Huiyuan; Liu, Bo.

Med Res Rev ; 2024 May 20.

Artigo em Inglês | MEDLINE | ID: mdl-38769656

11.

BiTSC 2: Bayesian inference of tumor clonal tree by joint analysis of single-cell SNV and CNA data.

Chen, Ziwei; Gong, Fuzhou; Wan, Lin; Ma, Liang.

Brief Bioinform ; 23(3)2022 05 13.

Artigo em Inglês | MEDLINE | ID: mdl-35368055

12.

A voltage-gated sodium channel is essential for the positive selection of CD4(+) T cells.

Lo, Wan-Lin; Donermeyer, David L; Allen, Paul M.

Nat Immunol ; 13(9): 880-7, 2012 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-22842345

13.

Accelerated 3D MR neurography of the brachial plexus using deep learning-constrained compressed sensing.

Hu, Si-Xian; Xiao, Yi; Peng, Wan-Lin; Zeng, Wen; Zhang, Yu; Zhang, Xiao-Yong; Ling, Chun-Tang; Li, Hai-Xia; Xia, Chun-Chao; Li, Zhen-Lin.

Eur Radiol ; 34(2): 842-851, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-37606664

14.

Safety and efficacy of melatonin supplementation as an add-on treatment for infantile epileptic spasms syndrome: A randomized, placebo-controlled, double-blind trial.

Sun, Yulin; Chen, Jian; Shi, Xiuyu; Li, Zhichao; Wan, Lin; Yan, Huimin; Chen, Yuehao; Wang, Jiaxin; Wang, Jing; Zou, Liping; Reiter, Russel; Zhang, Bo; Yang, Guang.

J Pineal Res ; 76(1): e12922, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-37909654

15.

Rapid Access to Tigliane, Ingenane, and Rhamnofolane Diterpenes from a Lathyrane Precursor via Biomimetic Skeleton Transformation Strategy.

Wang, Neng; Wan, Lin-Xi; Li, Xiaohuan; Xu, Jin-Bu; Gao, Feng.

J Nat Prod ; 87(5): 1479-1486, 2024 May 24.

Artigo em Inglês | MEDLINE | ID: mdl-38728656

16.

Comparative Safety Assessment of High and Low Doses of Anlotinib in Combination with PD-1 Monoclonal Antibody for Advanced Non-small Cell Lung Cancer Patients.

Wan, Lin; Xu, Yan; Liu, Liqiong; Huang, Hui.

Altern Ther Health Med ; 2024 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-38430167

17.

[Clinical and genetic analysis of a child with West syndrome due to a de novo variant of NEXMIF gene].

He, Wen; Liang, Yan; Yan, Huimin; Wan, Lin; Yang, Guang.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi ; 41(6): 725-729, 2024 Jun 10.

Artigo em Zh | MEDLINE | ID: mdl-38818558

18.

Dynamic inference of cell developmental complex energy landscape from time series single-cell transcriptomic data.

Jiang, Qi; Zhang, Shuo; Wan, Lin.

PLoS Comput Biol ; 18(1): e1009821, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-35073331

19.

Organocatalytic Asymmetric Morita-Baylis-Hillman Reaction of Isatins with Vinyl Sulfones.

He, Hong-Jiao; Wang, Rui-Qi; Wan, Lin-Xi; Zhou, Li-Yan; Li, Hong-Yan; Li, Guo-Bo; Xiao, You-Cai; Chen, Fen-Er.

J Org Chem ; 88(6): 3802-3807, 2023 Mar 17.

Artigo em Inglês | MEDLINE | ID: mdl-36822154

20.

Base-mediated chalcogenoaminative annulation of 2-alkynylanilines for direct access to 3-sulfenyl/selenyl-1H-indoles.

Chen, Wei-Ching; Bai, Rekha; Cheng, Wan-Lin; Peng, Chun-Yu; Reddy, Daggula Mallikarjuna; Badsara, Satpal Singh; Lee, Chin-Fa.

Org Biomol Chem ; 21(14): 3002-3013, 2023 Apr 05.

Artigo em Inglês | MEDLINE | ID: mdl-36942565

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