Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Inducible control of gene expression with destabilized Cre.

Sando, Richard; Baumgaertel, Karsten; Pieraut, Simon; Torabi-Rander, Nina; Wandless, Thomas J; Mayford, Mark; Maximov, Anton.

Nat Methods ; 10(11): 1085-8, 2013 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-24056874

2.

Using light to shape chemical gradients for parallel and automated analysis of chemotaxis.

Collins, Sean R; Yang, Hee Won; Bonger, Kimberly M; Guignet, Emmanuel G; Wandless, Thomas J; Meyer, Tobias.

Mol Syst Biol ; 11(4): 804, 2015 Apr 23.

Artigo em Inglês | MEDLINE | ID: mdl-25908733

3.

Visualizing cellular interactions with a generalized proximity reporter.

Sellmyer, Mark A; Bronsart, Laura; Imoto, Hiroshi; Contag, Christopher H; Wandless, Thomas J; Prescher, Jennifer A.

Proc Natl Acad Sci U S A ; 110(21): 8567-72, 2013 May 21.

Artigo em Inglês | MEDLINE | ID: mdl-23650381

4.

The E3 ubiquitin ligase UBE3C enhances proteasome processivity by ubiquitinating partially proteolyzed substrates.

Chu, Bernard W; Kovary, Kyle M; Guillaume, Johan; Chen, Ling-chun; Teruel, Mary N; Wandless, Thomas J.

J Biol Chem ; 288(48): 34575-87, 2013 Nov 29.

Artigo em Inglês | MEDLINE | ID: mdl-24158444

5.

Asparagine repeat function in a Plasmodium falciparum protein assessed via a regulatable fluorescent affinity tag.

Muralidharan, Vasant; Oksman, Anna; Iwamoto, Mari; Wandless, Thomas J; Goldberg, Daniel E.

Proc Natl Acad Sci U S A ; 108(11): 4411-6, 2011 Mar 15.

Artigo em Inglês | MEDLINE | ID: mdl-21368162

6.

Ubiquitin-Derived Fragment as a Peptide Linker for the Efficient Cleavage of a Target Protein from a Degron.

Utsugi, Yuki; Nishimura, Ken; Yamanaka, Satoshi; Nishino, Kohei; Kosako, Hidetaka; Sawasaki, Tatsuya; Shigemori, Hideyuki; Wandless, Thomas J; Miyamae, Yusaku.

ACS Chem Biol ; 19(2): 497-505, 2024 02 16.

Artigo em Inglês | MEDLINE | ID: mdl-38270585

7.

Small-molecule displacement of a cryptic degron causes conditional protein degradation.

Bonger, Kimberly M; Chen, Ling-chun; Liu, Corey W; Wandless, Thomas J.

Nat Chem Biol ; 7(8): 531-7, 2011 Jul 03.

Artigo em Inglês | MEDLINE | ID: mdl-21725303

8.

Ligand-switchable substrates for a ubiquitin-proteasome system.

Egeler, Emily L; Urner, Lorenz M; Rakhit, Rishi; Liu, Corey W; Wandless, Thomas J.

J Biol Chem ; 286(36): 31328-36, 2011 Sep 09.

Artigo em Inglês | MEDLINE | ID: mdl-21768107

9.

Chemical control of FGF-2 release for promoting calvarial healing with adipose stem cells.

Kwan, Matthew D; Sellmyer, Mark A; Quarto, Natalina; Ho, Andrew M; Wandless, Thomas J; Longaker, Michael T.

J Biol Chem ; 286(13): 11307-13, 2011 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-21262969

10.

Destabilizing domains derived from the human estrogen receptor.

Miyazaki, Yusuke; Imoto, Hiroshi; Chen, Ling-chun; Wandless, Thomas J.

J Am Chem Soc ; 134(9): 3942-5, 2012 Mar 07.

Artigo em Inglês | MEDLINE | ID: mdl-22332638

11.

A cAMP Sensor Based on Ligand-Dependent Protein Stabilization.

Sidoli, Mariapaola; Chen, Ling-Chun; Lu, Alexander J; Wandless, Thomas J; Talbot, William S.

ACS Chem Biol ; 17(8): 2024-2030, 2022 08 19.

Artigo em Inglês | MEDLINE | ID: mdl-35839076

12.

Evaluation of FKBP and DHFR based destabilizing domains in Saccharomyces cerevisiae.

Rakhit, Rishi; Edwards, Sarah R; Iwamoto, Mari; Wandless, Thomas J.

Bioorg Med Chem Lett ; 21(17): 4965-8, 2011 Sep 01.

Artigo em Inglês | MEDLINE | ID: mdl-21741238

13.

Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling.

Weber, Evan W; Parker, Kevin R; Sotillo, Elena; Lynn, Rachel C; Anbunathan, Hima; Lattin, John; Good, Zinaida; Belk, Julia A; Daniel, Bence; Klysz, Dorota; Malipatlolla, Meena; Xu, Peng; Bashti, Malek; Heitzeneder, Sabine; Labanieh, Louai; Vandris, Panayiotis; Majzner, Robbie G; Qi, Yanyan; Sandor, Katalin; Chen, Ling-Chun; Prabhu, Snehit; Gentles, Andrew J; Wandless, Thomas J; Satpathy, Ansuman T; Chang, Howard Y; Mackall, Crystal L.

Science ; 372(6537)2021 04 02.

Artigo em Inglês | MEDLINE | ID: mdl-33795428

14.

Rapid control of protein level in the apicomplexan Toxoplasma gondii.

Herm-Götz, Angelika; Agop-Nersesian, Carolina; Münter, Sylvia; Grimley, Joshua S; Wandless, Thomas J; Frischknecht, Friedrich; Meissner, Markus.

Nat Methods ; 4(12): 1003-5, 2007 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-17994029

15.

Dicistronic regulation of fluorescent proteins in the budding yeast Saccharomyces cerevisiae.

Edwards, Sarah R; Wandless, Thomas J.

Yeast ; 27(4): 229-36, 2010 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-20017217

16.

A Method for Conditional Regulation of Protein Stability in Native or Near-Native Form.

Miyamae, Yusaku; Chen, Ling-Chun; Utsugi, Yuki; Farrants, Helen; Wandless, Thomas J.

Cell Chem Biol ; 27(12): 1573-1581.e3, 2020 12 17.

Artigo em Inglês | MEDLINE | ID: mdl-33007216

17.

Correction to "A cAMP Sensor Based on Ligand-Dependent Protein Stabilization".

Sidoli, Mariapaola; Chen, Ling-Chun; Lu, Alexander J; Wandless, Thomas J; Talbot, William S.

ACS Chem Biol ; 19(4): 1022, 2024 Apr 19.

Artigo em Inglês | MEDLINE | ID: mdl-38456802

18.

Recent progress with FKBP-derived destabilizing domains.

Chu, Bernard W; Banaszynski, Laura A; Chen, Ling-chun; Wandless, Thomas J.

Bioorg Med Chem Lett ; 18(22): 5941-4, 2008 Nov 15.

Artigo em Inglês | MEDLINE | ID: mdl-18815033

19.

Synthesis and analysis of stabilizing ligands for FKBP-derived destabilizing domains.

Grimley, Joshua S; Chen, Denise A; Banaszynski, Laura A; Wandless, Thomas J.

Bioorg Med Chem Lett ; 18(2): 759-61, 2008 Jan 15.

Artigo em Inglês | MEDLINE | ID: mdl-18039574

20.

Conditional control of protein function.

Banaszynski, Laura A; Wandless, Thomas J.

Chem Biol ; 13(1): 11-21, 2006 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-16426967

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