Detalhe da pesquisa
1.
Expanded CUG repeats in DMPK transcripts adopt diverse hairpin conformations without influencing the structure of the flanking sequences.
RNA
; 25(4): 481-495, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30700578
2.
The nuclear concentration required for antisense oligonucleotide activity in myotonic dystrophy cells.
FASEB J
; 33(10): 11314-11325, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31311315
3.
Certainty-based marking in a formative assessment improves student course appreciation but not summative examination scores.
BMC Med Educ
; 19(1): 178, 2019 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-31151456
4.
CRISPR/Cas Applications in Myotonic Dystrophy: Expanding Opportunities.
Int J Mol Sci
; 20(15)2019 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31357652
5.
Recovery in the Myogenic Program of Congenital Myotonic Dystrophy Myoblasts after Excision of the Expanded (CTG)n Repeat.
Int J Mol Sci
; 20(22)2019 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31766224
6.
A low absolute number of expanded transcripts is involved in myotonic dystrophy type 1 manifestation in muscle.
Hum Mol Genet
; 25(8): 1648-62, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26908607
7.
CRISPR/Cas9-Induced (CTGâ CAG)n Repeat Instability in the Myotonic Dystrophy Type 1 Locus: Implications for Therapeutic Genome Editing.
Mol Ther
; 25(1): 24-43, 2017 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28129118
8.
Antisense transcription of the myotonic dystrophy locus yields low-abundant RNAs with and without (CAG)n repeat.
RNA Biol
; 14(10): 1374-1388, 2017 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28102759
9.
Chromosome-wide nucleosome replacement and H3.3 incorporation during mammalian meiotic sex chromosome inactivation.
Nat Genet
; 39(2): 251-8, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17237782
10.
Differentiation shifts from a reversible to an irreversible heterochromatin state at the DM1 locus.
Nat Commun
; 15(1): 3270, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38627364
11.
Block or degrade? Balancing on- and off-target effects of antisense strategies against transcripts with expanded triplet repeats in DM1.
Mol Ther Nucleic Acids
; 32: 622-636, 2023 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37200862
12.
Abnormal actomyosin assembly in proliferating and differentiating myoblasts upon expression of a cytosolic DMPK isoform.
Biochim Biophys Acta
; 1813(5): 867-77, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21295081
13.
Phosphorylation target site specificity for AGC kinases DMPK E and Lats2.
J Cell Biochem
; 113(6): 2126-35, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22492269
14.
Molecular therapy in myotonic dystrophy: focus on RNA gain-of-function.
Hum Mol Genet
; 19(R1): R90-7, 2010 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20406734
15.
Triplet-repeat oligonucleotide-mediated reversal of RNA toxicity in myotonic dystrophy.
Proc Natl Acad Sci U S A
; 106(33): 13915-20, 2009 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19667189
16.
Imaging of CPP Delivery Mechanisms of Oligonucleotides.
Methods Mol Biol
; 2383: 197-210, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34766291
17.
A comprehensive atlas of fetal splicing patterns in the brain of adult myotonic dystrophy type 1 patients.
NAR Genom Bioinform
; 4(1): lqac016, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35274098
18.
The mouse mismatch repair protein, MSH3, is a nucleoplasmic protein that aggregates into denser nuclear bodies under conditions of stress.
J Cell Biochem
; 112(6): 1612-21, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21344488
19.
Systemic cell therapy for muscular dystrophies : The ultimate transplantable muscle progenitor cell and current challenges for clinical efficacy.
Stem Cell Rev Rep
; 17(3): 878-899, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33349909
20.
In Vitro Synthesis and RNA Structure Probing of CUG Triplet Repeat RNA.
Methods Mol Biol
; 2056: 187-202, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31586349