Detalhe da pesquisa
1.
A Sensitive Technique Unravels the Kinetics of Activation and Trans-Cleavage of CRISPR-Cas Systems.
Angew Chem Int Ed Engl
; 63(22): e202404069, 2024 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38526321
2.
Development of a DNAzyme Walker for the Detection of APE1 in Living Cancer Cells.
Anal Chem
; 95(40): 14990-14997, 2023 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37725609
3.
Zika Virus Induces Mitotic Catastrophe in Human Neural Progenitors by Triggering Unscheduled Mitotic Entry in the Presence of DNA Damage While Functionally Depleting Nuclear PNKP.
J Virol
; 96(9): e0033322, 2022 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35412344
4.
Optimized Carbohydrate-Based Nanogel Formulation to Sensitize Hypoxic Tumors.
Mol Pharm
; 20(6): 3100-3114, 2023 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37148327
5.
Biodistribution and Activity of EGFR Targeted Polymeric Micelles Delivering a New Inhibitor of DNA Repair to Orthotopic Colorectal Cancer Xenografts with Metastasis.
Mol Pharm
; 19(6): 1825-1838, 2022 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35271294
6.
Domain analysis of PNKP-XRCC1 interactions: Influence of genetic variants of XRCC1.
J Biol Chem
; 294(2): 520-530, 2019 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30446622
7.
Synthesis and Analysis of 64Cu-Labeled GE11-Modified Polymeric Micellar Nanoparticles for EGFR-Targeted Molecular Imaging in a Colorectal Cancer Model.
Mol Pharm
; 17(5): 1470-1481, 2020 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32233491
8.
Microhomology-mediated end joining is activated in irradiated human cells due to phosphorylation-dependent formation of the XRCC1 repair complex.
Nucleic Acids Res
; 45(5): 2585-2599, 2017 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27994036
9.
Structural and functional characterization of the PNKP-XRCC4-LigIV DNA repair complex.
Nucleic Acids Res
; 45(10): 6238-6251, 2017 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28453785
10.
RUNX3 Promotes the Tumorigenic Phenotype in KGN, a Human Granulosa Cell Tumor-Derived Cell Line.
Int J Mol Sci
; 20(14)2019 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31311113
11.
The Rev1 interacting region (RIR) motif in the scaffold protein XRCC1 mediates a low-affinity interaction with polynucleotide kinase/phosphatase (PNKP) during DNA single-strand break repair.
J Biol Chem
; 292(39): 16024-16031, 2017 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28821613
12.
Nanoencapsulation of Novel Inhibitors of PNKP for Selective Sensitization to Ionizing Radiation and Irinotecan and Induction of Synthetic Lethality.
Mol Pharm
; 15(6): 2316-2326, 2018 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29688721
13.
Characterization of DNA Substrate Binding to the Phosphatase Domain of the DNA Repair Enzyme Polynucleotide Kinase/Phosphatase.
Biochemistry
; 56(12): 1737-1745, 2017 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28276686
14.
Prolonged withdrawal from cocaine self-administration affects prefrontal cortex- and basolateral amygdala-nucleus accumbens core circuits but not accumbens GABAergic local interneurons.
Addict Biol
; 22(6): 1682-1694, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27457780
15.
DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair.
Nucleic Acids Res
; 43(2): 875-92, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25539916
16.
Characterization of Plasmodium falciparum ATP-dependent DNA helicase RuvB3.
Malar J
; 15(1): 526, 2016 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27809838
17.
Key Issues Related to Cryopreservation and Storage of Stem Cells and Cancer Stem Cells: Protecting Biological Integrity.
Adv Exp Med Biol
; 951: 1-12, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27837550
18.
Tidying up loose ends: the role of polynucleotide kinase/phosphatase in DNA strand break repair.
Trends Biochem Sci
; 36(5): 262-71, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21353781
19.
Biobanking in the Twenty-First Century: Driving Population Metrics into Biobanking Quality.
Adv Exp Med Biol
; 864: 95-114, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26420616
20.
Role of polynucleotide kinase/phosphatase in mitochondrial DNA repair.
Nucleic Acids Res
; 40(8): 3484-95, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22210862