Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Sequential antigen loss and branching evolution in lymphoma after CD19- and CD20-targeted T-cell-redirecting therapy.

Duell, Johannes; Leipold, Alexander M; Appenzeller, Silke; Fuhr, Viktoria; Rauert-Wunderlich, Hilka; Da Via, Matteo; Dietrich, Oliver; Toussaint, Christophe; Imdahl, Fabian; Eisele, Florian; Afrin, Nazia; Grundheber, Lars; Einsele, Hermann; Weinhold, Niels; Rosenwald, Andreas; Topp, Max S; Saliba, Antoine-Emmanuel; Rasche, Leo.

Blood ; 143(8): 685-696, 2024 Feb 22.

Artigo em Inglês | MEDLINE | ID: mdl-37976456

2.

EVIDENCE meta-analysis: evaluating minimal residual disease as an intermediate clinical endpoint for multiple myeloma.

Landgren, Ola; Prior, Thomas J; Masterson, Tara; Heuck, Christoph; Bueno, Orlando F; Dash, Ajeeta B; Einsele, Hermann; Goldschmidt, Hartmut; Knop, Stefan; Li, Cong; Mellqvist, Ulf-Henrik; McFadden, Ian; Oprea, Corina; Ross, Jeremy A; Talpes, Mihaela; Hydren, Jay; Ahlstrom, Jenny; Kazandjian, Dickran; Weinhold, Niels; Zhang, Rick; Stetler-Stevenson, Maryalice; Marti, Gerald E; Devlin, Sean M.

Blood ; 2024 05 20.

Artigo em Inglês | MEDLINE | ID: mdl-38768337

3.

The biological and clinical impact of deletions before and after large chromosomal gains in multiple myeloma.

Cirrincione, Anthony M; Poos, Alexandra M; Ziccheddu, Bachisio; Kaddoura, Marcella; Baertsch, Marc-Andrea; Maclachlan, Kylee H; Chojnacka, Monika; Diamond, Benjamin T; John, Lukas; Reichert, Philipp; Huhn, Stefanie; Blaney, Patrick; Gagler, Dylan C; Rippe, Karsten; Zhang, Yanming; Dogan, Ahmet; Lesokhin, Alexander M; Davies, Faith E; Goldschmidt, Hartmut; Fenk, Roland; Weisel, Katja C; Mai, Elias K; Korde, Neha; Morgan, Gareth J; Usmani, Saad Z; Landgren, Ola; Raab, Marc S; Weinhold, Niels; Maura, Francesco.

Blood ; 2024 May 10.

Artigo em Inglês | MEDLINE | ID: mdl-38728430

4.

Resolving therapy resistance mechanisms in multiple myeloma by multiomics subclone analysis.

Poos, Alexandra M; Prokoph, Nina; Przybilla, Moritz J; Mallm, Jan-Philipp; Steiger, Simon; Seufert, Isabelle; John, Lukas; Tirier, Stephan M; Bauer, Katharina; Baumann, Anja; Rohleder, Jennifer; Munawar, Umair; Rasche, Leo; Kortüm, K Martin; Giesen, Nicola; Reichert, Philipp; Huhn, Stefanie; Müller-Tidow, Carsten; Goldschmidt, Hartmut; Stegle, Oliver; Raab, Marc S; Rippe, Karsten; Weinhold, Niels.

Blood ; 142(19): 1633-1646, 2023 11 09.

Artigo em Inglês | MEDLINE | ID: mdl-37390336

5.

A phase 2 clinical trial of combined BRAF/MEK inhibition for BRAFV600E-mutated multiple myeloma.

Giesen, Nicola; Chatterjee, Manik; Scheid, Christof; Poos, Alexandra M; Besemer, Britta; Miah, Kaya; Benner, Axel; Becker, Nicole; Moehler, Thomas; Metzler, Ivana; Khandanpour, Cyrus; Seidel-Glaetzer, Andrea; Trautmann-Grill, Karolin; Kortüm, K Martin; Müller-Tidow, Carsten; Mechtersheimer, Gunhild; Goeppert, Benjamin; Stenzinger, Albrecht; Weinhold, Niels; Goldschmidt, Hartmut; Weisel, Katja; Raab, Marc S.

Blood ; 141(14): 1685-1690, 2023 04 06.

Artigo em Inglês | MEDLINE | ID: mdl-36608320

6.

International Myeloma Working Group immunotherapy committee consensus guidelines and recommendations for optimal use of T-cell-engaging bispecific antibodies in multiple myeloma.

Rodriguez-Otero, Paula; Usmani, Saad; Cohen, Adam D; van de Donk, Niels W C J; Leleu, Xavier; Gállego Pérez-Larraya, Jaime; Manier, Salomon; Nooka, Ajay K; Mateos, Maria Victoria; Einsele, Hermann; Minnema, Monique; Cavo, Michele; Derman, Benjamin A; Puig, Noemi; Gay, Francesca; Ho, P Joy; Chng, Wee-Joo; Kastritis, Efstathios; Gahrton, Gösta; Weisel, Katja; Nagarajan, Chandramouli; Schjesvold, Fredik; Mikhael, Joseph; Costa, Luciano; Raje, Noopur S; Zamagni, Elena; Hájek, Roman; Weinhold, Niels; Yong, Kwee; Ye, Jing Christine; Sidhana, Surbhi; Merlini, Giampaolo; Martin, Tom; Lin, Yi; Chari, Ajai; Popat, Rakesh; Kaufman, Jonathan L.

Lancet Oncol ; 25(5): e205-e216, 2024 05.

Artigo em Inglês | MEDLINE | ID: mdl-38697166

7.

Reproducible Radiomics Features from Multi-MRI-Scanner Test-Retest-Study: Influence on Performance and Generalizability of Models.

Wennmann, Markus; Rotkopf, Lukas T; Bauer, Fabian; Hielscher, Thomas; Kächele, Jessica; Mai, Elias K; Weinhold, Niels; Raab, Marc-Steffen; Goldschmidt, Hartmut; Weber, Tim F; Schlemmer, Heinz-Peter; Delorme, Stefan; Maier-Hein, Klaus; Neher, Peter.

J Magn Reson Imaging ; 2024 May 11.

Artigo em Inglês | MEDLINE | ID: mdl-38733369

8.

Clonal hematopoiesis with DNMT3A and PPM1D mutations impairs regeneration in autologous stem cell transplant recipients.

Stelmach, Patrick; Richter, Sarah; Sauer, Sandra; Fabre, Margarete A; Gu, Muxin; Rohde, Christian; Janssen, Maike; Liebers, Nora; Proynova, Rumyana; Weinhold, Niels; Raab, Marc S; Goldschmidt, Hartmut; Besenbeck, Birgit; Pavel, Petra; Laier, Sascha; Trumpp, Andreas; Dietrich, Sascha; Vassiliou, George S; Müller-Tidow, Carsten.

Haematologica ; 108(12): 3308-3320, 2023 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-37381752

9.

Application of an artificial intelligence-based tool in [¹⁸F]FDG PET/CT for the assessment of bone marrow involvement in multiple myeloma.

Sachpekidis, Christos; Enqvist, Olof; Ulén, Johannes; Kopp-Schneider, Annette; Pan, Leyun; Jauch, Anna; Hajiyianni, Marina; John, Lukas; Weinhold, Niels; Sauer, Sandra; Goldschmidt, Hartmut; Edenbrandt, Lars; Dimitrakopoulou-Strauss, Antonia.

Eur J Nucl Med Mol Imaging ; 50(12): 3697-3708, 2023 10.

Artigo em Inglês | MEDLINE | ID: mdl-37493665

10.

Stem cell collection after lenalidomide, bortezomib and dexamethasone plus elotuzumab or isatuximab in newly diagnosed multiple myeloma patients: a single centre experience from the GMMG-HD6 and -HD7 trials.

Kauer, Joseph; Freundt, Emma P; Schmitt, Anita; Weinhold, Niels; Mai, Elias K; Müller-Tidow, Carsten; Goldschmidt, Hartmut; Raab, Marc S; Kriegsmann, Katharina; Sauer, Sandra.

BMC Cancer ; 23(1): 1132, 2023 Nov 21.

Artigo em Inglês | MEDLINE | ID: mdl-37990162

11.

Cyclophosphamide etoposide dexamethasone as salvage and bridging therapy in relapsed refractory and extramedullary multiple myeloma.

Kauer, Joseph; Sester, Lilli Sophie; Kriegsmann, Katharina; Weinhold, Niels; Ober, Michael; Müller-Tidow, Carsten; Goldschmidt, Hartmut; Raab, Marc-Steffen; Sauer, Sandra.

Hematol Oncol ; 41(3): 453-462, 2023 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-36680428

12.

(Smoldering) multiple myeloma: mismatch between tumor load estimated from bone marrow biopsy at iliac crest and tumor load shown by MRI.

Bauer, Fabian; Sauer, Sandra; Weinhold, Niels; Delorme, Stefan; Wennmann, Markus.

Skeletal Radiol ; 52(12): 2513-2518, 2023 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-37300710

13.

Polymorphisms within Autophagy-Related Genes as Susceptibility Biomarkers for Multiple Myeloma: A Meta-Analysis of Three Large Cohorts and Functional Characterization.

Clavero, Esther; Sanchez-Maldonado, José Manuel; Macauda, Angelica; Ter Horst, Rob; Sampaio-Marques, Belém; Jurczyszyn, Artur; Clay-Gilmour, Alyssa; Stein, Angelika; Hildebrandt, Michelle A T; Weinhold, Niels; Buda, Gabriele; García-Sanz, Ramón; Tomczak, Waldemar; Vogel, Ulla; Jerez, Andrés; Zawirska, Daria; Watek, Marzena; Hofmann, Jonathan N; Landi, Stefano; Spinelli, John J; Butrym, Aleksandra; Kumar, Abhishek; Martínez-López, Joaquín; Galimberti, Sara; Sarasquete, María Eugenia; Subocz, Edyta; Iskierka-Jazdzewska, Elzbieta; Giles, Graham G; Rybicka-Ramos, Malwina; Kruszewski, Marcin; Abildgaard, Niels; Verdejo, Francisco García; Sánchez Rovira, Pedro; da Silva Filho, Miguel Inacio; Kadar, Katalin; Razny, Malgorzata; Cozen, Wendy; Pelosini, Matteo; Jurado, Manuel; Bhatti, Parveen; Dudzinski, Marek; Druzd-Sitek, Agnieszka; Orciuolo, Enrico; Li, Yang; Norman, Aaron D; Zaucha, Jan Maciej; Reis, Rui Manuel; Markiewicz, Miroslaw; Rodríguez Sevilla, Juan José; Andersen, Vibeke.

Int J Mol Sci ; 24(10)2023 May 09.

Artigo em Inglês | MEDLINE | ID: mdl-37239846

14.

Comprehensive genomic analysis of refractory multiple myeloma reveals a complex mutational landscape associated with drug resistance and novel therapeutic vulnerabilities.

Giesen, Nicola; Paramasivam, Nagarajan; Toprak, Umut H; Huebschmann, Daniel; Xu, Jing; Uhrig, Sebastian; Samur, Mehmet; Bähr, Stella; Fröhlich, Martina; Mughal, Sadaf S; Mai, Elias K; Jauch, Anna; Müller-Tidow, Carsten; Brors, Benedikt; Munshi, Nikhil; Goldschmidt, Hartmut; Weinhold, Niels; Schlesner, Matthias; Raab, Marc S.

Haematologica ; 107(8): 1891-1901, 2022 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-35045690

15.

Daratumumab in high-risk relapsed/refractory multiple myeloma patients: adverse effect of chromosome 1q21 gain/amplification and GEP70 status on outcome.

Mohan, Meera; Weinhold, Niels; Schinke, Carolina; Thanedrarajan, Sharmilan; Rasche, Leo; Sawyer, Jeffrey R; Tian, Erming; van Rhee, Frits; Zangari, Maurizio.

Br J Haematol ; 189(1): 67-71, 2020 04.

Artigo em Inglês | MEDLINE | ID: mdl-31820442

16.

When a solitary plasmacytoma is just the beginning.

Rasche, Leo; Weinhold, Niels.

Blood ; 142(22): 1849-1850, 2023 11 30.

Artigo em Inglês | MEDLINE | ID: mdl-38032673

17.

The presence of large focal lesions is a strong independent prognostic factor in multiple myeloma.

Rasche, Leo; Angtuaco, Edgardo J; Alpe, Terri L; Gershner, Grant H; McDonald, James E; Samant, Rohan S; Kumar, Manoj; Van Hemert, Rudy; Epstein, Joshua; Deshpande, Shayu; Tytarenko, Ruslana; Yaccoby, Shmuel; Hillengass, Jens; Thanendrarajan, Sharmilan; Schinke, Carolina; van Rhee, Frits; Zangari, Maurizio; Walker, Brian A; Barlogie, Bart; Morgan, Gareth J; Davies, Faith E; Weinhold, Niels.

Blood ; 132(1): 59-66, 2018 07 05.

Artigo em Inglês | MEDLINE | ID: mdl-29784643

18.

Transcriptome-wide association study of multiple myeloma identifies candidate susceptibility genes.

Went, Molly; Kinnersley, Ben; Sud, Amit; Johnson, David C; Weinhold, Niels; Försti, Asta; van Duin, Mark; Orlando, Giulia; Mitchell, Jonathan S; Kuiper, Rowan; Walker, Brian A; Gregory, Walter M; Hoffmann, Per; Jackson, Graham H; Nöthen, Markus M; da Silva Filho, Miguel Inacio; Thomsen, Hauke; Broyl, Annemiek; Davies, Faith E; Thorsteinsdottir, Unnur; Hansson, Markus; Kaiser, Martin; Sonneveld, Pieter; Goldschmidt, Hartmut; Stefansson, Kari; Hemminki, Kari; Nilsson, Björn; Morgan, Gareth J; Houlston, Richard S.

Hum Genomics ; 13(1): 37, 2019 08 20.

Artigo em Inglês | MEDLINE | ID: mdl-31429796

19.

Summary of the Second Annual BMT CTN Myeloma Intergroup Workshop on Minimal Residual Disease and Immune Profiling.

Holstein, Sarah A; Ye, J Christine; Howard, Alan; Bhutani, Manisha; Gormley, Nicole; Hahn, Theresa; Hillengass, Jens; Krishnan, Amrita; Landgren, C Ola; Munshi, Nikhil C; Oliva, Stefania; Owen, Roger G; Pasquini, Marcelo C; Puig, Noemi; Weinhold, Niels; Weisel, Katja; McCarthy, Philip L.

Biol Blood Marrow Transplant ; 25(3): e89-e97, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30408566

20.

Low expression of hexokinase-2 is associated with false-negative FDG-positron emission tomography in multiple myeloma.

Rasche, Leo; Angtuaco, Edgardo; McDonald, James E; Buros, Amy; Stein, Caleb; Pawlyn, Charlotte; Thanendrarajan, Sharmilan; Schinke, Carolina; Samant, Rohan; Yaccoby, Shmuel; Walker, Brian A; Epstein, Joshua; Zangari, Maurizio; van Rhee, Frits; Meissner, Tobias; Goldschmidt, Hartmut; Hemminki, Kari; Houlston, Richard; Barlogie, Bart; Davies, Faith E; Morgan, Gareth J; Weinhold, Niels.

Blood ; 130(1): 30-34, 2017 07 06.

Artigo em Inglês | MEDLINE | ID: mdl-28432222

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