Detalhe da pesquisa
1.
Behavioural immune landscapes of inflammation.
Nature
; 601(7893): 415-421, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34987220
2.
Functions and mechanisms of the GPCR adaptor protein Norbin.
Biochem Soc Trans
; 51(4): 1545-1558, 2023 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37503670
3.
PtdIns(3,4,5)P3-dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis.
Proc Natl Acad Sci U S A
; 117(45): 28056-28067, 2020 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33097662
4.
Truncating PREX2 mutations activate its GEF activity and alter gene expression regulation in NRAS-mutant melanoma.
Proc Natl Acad Sci U S A
; 113(9): E1296-305, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26884185
5.
Rac-GTPases and Rac-GEFs in neutrophil adhesion, migration and recruitment.
Eur J Clin Invest
; 48 Suppl 2: e12939, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-29682742
6.
Platelets in neutrophil recruitment to sites of inflammation.
Curr Opin Hematol
; 24(1): 23-31, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27820736
7.
Norbin Stimulates the Catalytic Activity and Plasma Membrane Localization of the Guanine-Nucleotide Exchange Factor P-Rex1.
J Biol Chem
; 291(12): 6359-75, 2016 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26792863
8.
P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation.
Blood
; 125(7): 1146-58, 2015 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25538043
9.
Small GTPases and their guanine-nucleotide exchange factors and GTPase-activating proteins in neutrophil recruitment.
Curr Opin Hematol
; 23(1): 44-54, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26619317
10.
P-Rex1 and Vav1 cooperate in the regulation of formyl-methionyl-leucyl-phenylalanine-dependent neutrophil responses.
J Immunol
; 186(3): 1467-76, 2011 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21178006
11.
The guanine-nucleotide-exchange factor P-Rex1 is activated by protein phosphatase 1α.
Biochem J
; 443(1): 173-83, 2012 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22242915
12.
Dock2 generates characteristic spatiotemporal patterns of Rac activity to regulate neutrophil polarisation, migration and phagocytosis.
Front Immunol
; 14: 1180886, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37383235
13.
The GPCR adaptor protein Norbin regulates S1PR1 trafficking and the morphology, cell cycle and survival of PC12 cells.
Sci Rep
; 13(1): 18237, 2023 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37880240
14.
The Rac-GEF Tiam1 controls integrin-dependent neutrophil responses.
Front Immunol
; 14: 1223653, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38077328
15.
Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities.
J Biol Chem
; 286(22): 19905-16, 2011 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-21460216
16.
Age-related decline in the resistance of mice to bacterial infection and in LPS/TLR4 pathway-dependent neutrophil responses.
Front Immunol
; 13: 888415, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36090969
17.
P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination.
Proc Natl Acad Sci U S A
; 105(11): 4483-8, 2008 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-18334636
18.
Rho Family GTPases and Rho GEFs in Glucose Homeostasis.
Cells
; 10(4)2021 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33923452
19.
P-Rex1 Controls Sphingosine 1-Phosphate Receptor Signalling, Morphology, and Cell-Cycle Progression in Neuronal Cells.
Cells
; 10(9)2021 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34572121
20.
The GPCR adaptor protein norbin suppresses the neutrophil-mediated immunity of mice to pneumococcal infection.
Blood Adv
; 5(16): 3076-3091, 2021 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34402884