Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

The Transcriptome and DNA Methylome Landscapes of Human Primordial Germ Cells.

Guo, Fan; Yan, Liying; Guo, Hongshan; Li, Lin; Hu, Boqiang; Zhao, Yangyu; Yong, Jun; Hu, Yuqiong; Wang, Xiaoye; Wei, Yuan; Wang, Wei; Li, Rong; Yan, Jie; Zhi, Xu; Zhang, Yan; Jin, Hongyan; Zhang, Wenxin; Hou, Yu; Zhu, Ping; Li, Jingyun; Zhang, Ling; Liu, Sirui; Ren, Yixin; Zhu, Xiaohui; Wen, Lu; Gao, Yi Qin; Tang, Fuchou; Qiao, Jie.

Cell ; 161(6): 1437-52, 2015 Jun 04.

Artigo em Inglês | MEDLINE | ID: mdl-26046443

2.

Reconstructing complex tissues from single-cell analyses.

Wen, Lu; Tang, Fuchou.

Cell ; 157(4): 771-3, 2014 May 08.

Artigo em Inglês | MEDLINE | ID: mdl-24813603

3.

Human Germline Cell Development: from the Perspective of Single-Cell Sequencing.

Wen, Lu; Tang, Fuchou.

Mol Cell ; 76(2): 320-328, 2019 10 17.

Artigo em Inglês | MEDLINE | ID: mdl-31563431

4.

scNanoHi-C: a single-cell long-read concatemer sequencing method to reveal high-order chromatin structures within individual cells.

Li, Wen; Lu, Jiansen; Lu, Ping; Gao, Yun; Bai, Yichen; Chen, Kexuan; Su, Xinjie; Li, Mengyao; Liu, Jun'e; Chen, Yijun; Wen, Lu; Tang, Fuchou.

Nat Methods ; 20(10): 1493-1505, 2023 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-37640936

5.

Serum Interleukin-6 and Serum Ferritin Levels Are the Independent Risk Factors for Pneumonia in Elderly Patients.

Yuan, Hao; Tian, Jing; Wen, Lu.

Crit Rev Immunol ; 44(5): 113-122, 2024.

Artigo em Inglês | MEDLINE | ID: mdl-38618733

6.

Reconstituting the transcriptome and DNA methylome landscapes of human implantation.

Zhou, Fan; Wang, Rui; Yuan, Peng; Ren, Yixin; Mao, Yunuo; Li, Rong; Lian, Ying; Li, Junsheng; Wen, Lu; Yan, Liying; Qiao, Jie; Tang, Fuchou.

Nature ; 572(7771): 660-664, 2019 08.

Artigo em Inglês | MEDLINE | ID: mdl-31435013

7.

Long-read-based single sperm genome sequencing for chromosome-wide haplotype phasing of both SNPs and SVs.

Xie, Haoling; Li, Wen; Guo, Yuqing; Su, Xinjie; Chen, Kexuan; Wen, Lu; Tang, Fuchou.

Nucleic Acids Res ; 51(15): 8020-8034, 2023 08 25.

Artigo em Inglês | MEDLINE | ID: mdl-37351613

8.

Integrating single-cell datasets with ambiguous batch information by incorporating molecular network features.

Dong, Ji; Zhou, Peijie; Wu, Yichong; Chen, Yidong; Xie, Haoling; Gao, Yuan; Lu, Jiansen; Yang, Jingwei; Zhang, Xiannian; Wen, Lu; Li, Tiejun; Tang, Fuchou.

Brief Bioinform ; 23(1)2022 01 17.

Artigo em Inglês | MEDLINE | ID: mdl-34553223

9.

The gut microbiome modulates the transformation of microglial subtypes.

Huang, Yu; Wu, Jing; Zhang, Hanping; Li, Yifan; Wen, Lu; Tan, Xunmin; Cheng, Ke; Liu, Yiyun; Pu, Juncai; Liu, Lanxiang; Wang, Haiyang; Li, Wenxia; Perry, Seth W; Wong, Ma-Li; Licinio, Julio; Zheng, Peng; Xie, Peng.

Mol Psychiatry ; 28(4): 1611-1621, 2023 04.

Artigo em Inglês | MEDLINE | ID: mdl-36914812

10.

Integrated transcriptomics and epigenomics reveal chamber-specific and species-specific characteristics of human and mouse hearts.

Gao, Junpeng; Zheng, Yuxuan; Li, Lin; Lu, Minjie; Chen, Xiangjian; Wang, Yu; Li, Yanna; Liu, Xiaomeng; Gao, Yun; Mao, Yunuo; Zhao, Peng; Zhang, Jinan; Tang, Fuchou; Song, Lei; Wen, Lu; Wang, Jizheng.

PLoS Biol ; 19(5): e3001229, 2021 05.

Artigo em Inglês | MEDLINE | ID: mdl-34003819

11.

Induction of therapeutic immunity and cancer eradication through biofunctionalized liposome-like nanovesicles derived from irradiated-cancer cells.

Deng, Suke; Wang, Jiacheng; Hu, Yan; Sun, Yajie; Yang, Xiao; Zhang, Bin; Deng, Yue; Wei, Wenwen; Zhang, Zhanjie; Wen, Lu; Qin, You; Huang, Fang; Sheng, Yuhan; Wan, Chao; Yang, Kunyu.

J Nanobiotechnology ; 22(1): 156, 2024 Apr 08.

Artigo em Inglês | MEDLINE | ID: mdl-38589867

12.

Relationships of tumor differentiation and immune infiltration in gastric cancers revealed by single-cell RNA-seq analyses.

Zhou, Xin; Yang, Jingwei; Lu, Yongqu; Ma, Yanpeng; Meng, Yan; Li, Qingqing; Gao, Junpeng; Jiang, Zhaoyu; Guo, Limei; Wang, Wei; Liu, Yun; Wen, Lu; Kai, Miao; Fu, Wei; Tang, Fuchou.

Cell Mol Life Sci ; 80(2): 57, 2023 Feb 02.

Artigo em Inglês | MEDLINE | ID: mdl-36729271

13.

De novo assembly of human genome at single-cell levels.

Xie, Haoling; Li, Wen; Hu, Yuqiong; Yang, Cheng; Lu, Jiansen; Guo, Yuqing; Wen, Lu; Tang, Fuchou.

Nucleic Acids Res ; 50(13): 7479-7492, 2022 07 22.

Artigo em Inglês | MEDLINE | ID: mdl-35819189

14.

Inactivation of the TGF-ß1/ALK5 axis enhances club cell function and alleviates lung tissue damage to ameliorate COPD progression through the MEK/ERK signaling pathway.

Tian, Jing; Ouyang, Hui; Wu, Jie; Wen, Lu; Li, Xiaoping; Yang, Fangying; Yuan, Hao.

Gen Physiol Biophys ; 43(1): 37-48, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-38312033

15.

Chiral growth of adherent filopodia.

Li, Wenhong; Chung, Wen-Lu; Kozlov, Michael M; Medalia, Ohad; Geiger, Benjamin; Bershadsky, Alexander D.

Biophys J ; 122(18): 3704-3721, 2023 09 19.

Artigo em Inglês | MEDLINE | ID: mdl-37301982

16.

Primary cilia: Structure, dynamics, and roles in cancer cells and tumor microenvironment.

Guan, Yi-Ting; Zhang, Chong; Zhang, Hong-Yong; Wei, Wen-Lu; Yue, Wei; Zhao, Wei; Zhang, Dong-Hui.

J Cell Physiol ; 238(8): 1788-1807, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37565630

17.

Fibroblast Growth Factor 2 Is Produced By Renal Tubular Cells to Act as a Paracrine Factor in Maladaptive Kidney Repair After Cisplatin Nephrotoxicity.

Hu, Xiaoru; Ma, Zhengwei; Li, Siyao; Wen, Lu; Huo, Yuqing; Wu, Guangyu; Manicassamy, Santhakumar; Dong, Zheng.

Lab Invest ; 103(3): 100009, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36925200

18.

Differential cellular responses to adhesive interactions with galectin-8- and fibronectin-coated substrates.

Li, Wenhong; Sancho, Ana; Chung, Wen-Lu; Vinik, Yaron; Groll, Jürgen; Zick, Yehiel; Medalia, Ohad; Bershadsky, Alexander D; Geiger, Benjamin.

J Cell Sci ; 134(8)2021 04 15.

Artigo em Inglês | MEDLINE | ID: mdl-33722978

19.

Identifying Proliferative Hepatocellular Carcinoma at Pretreatment CT: Implications for Therapeutic Outcomes after Transarterial Chemoembolization.

Bao, Yan; Li, Jun-Xiang; Zhou, Peng; Tong, Yao; Wang, Li-Zhou; Chang, De-Hua; Cai, Wen-Wu; Wen, Lu; Liu, Jun; Xiao, Yu-Dong.

Radiology ; 308(2): e230457, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37642572

20.

Safety and efficacy of apatinib in patients with advanced gastric or gastroesophageal junction adenocarcinoma after the failure of two or more lines of chemotherapy (AHEAD): a prospective, single-arm, multicenter, phase IV study.

Li, Jin; Qin, Shukui; Wen, Lu; Wang, Junsheng; Deng, Wenying; Guo, Weijian; Jia, Tongfu; Jiang, Da; Zhang, Guifang; He, Yifu; Ba, Yi; Zhong, Haijun; Wang, Lin; Lin, Xiaoyan; Yang, Jianwei; Zhao, Jun; Bai, Yuxian; Wu, Xiangyuan; Gao, Feng; Sun, Guogui; Wu, Yongjuan; Ye, Feng; Wang, Qiong; Xie, Zhong; Yi, Tienan; Huang, Yong; Yu, Guohua; Lu, Lin; Yuan, Ying; Li, Wei; Liu, Likun; Sun, Yuping; Sun, Ying; Yin, Lifeng; Hou, Zhiguo.

BMC Med ; 21(1): 173, 2023 05 05.

Artigo em Inglês | MEDLINE | ID: mdl-37147645

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