Detalhe da pesquisa
1.
Design and Synthesis of 56 Shape-Diverse 3D Fragments.
Chemistry
; 26(41): 8969-8975, 2020 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32315100
2.
Potent bicyclic inhibitors of malarial cGMP-dependent protein kinase: approaches to combining improvements in cell potency, selectivity and structural novelty.
Bioorg Med Chem Lett
; 29(19): 126610, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31471167
3.
Potent inhibitors of malarial P. Falciparum protein kinase G: Improving the cell activity of a series of imidazopyridines.
Bioorg Med Chem Lett
; 29(3): 509-514, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30553738
4.
Lead-oriented synthesis: Investigation of organolithium-mediated routes to 3-D scaffolds and 3-D shape analysis of a virtual lead-like library.
Bioorg Med Chem
; 23(11): 2680-94, 2015 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25936257
5.
Exploration of piperidine 3D fragment chemical space: synthesis and 3D shape analysis of fragments derived from 20 regio- and diastereoisomers of methyl substituted pipecolinates.
RSC Med Chem
; 13(12): 1614-1620, 2022 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36545433
6.
A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission.
Nat Commun
; 8(1): 430, 2017 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28874661