Detalhe da pesquisa
1.
Structure guided drug design to develop kallikrein 5 inhibitors to treat Netherton syndrome.
Bioorg Med Chem Lett
; 29(12): 1454-1458, 2019 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31005442
2.
Kallikrein 5 inhibitors identified through structure based drug design in search for a treatment for Netherton Syndrome.
Bioorg Med Chem Lett
; 29(6): 821-825, 2019 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30691925
3.
Oxygenated Cyclopentenones via the Pauson-Khand Reaction of Silyl Enol Ether Substrates.
Org Lett
; 24(14): 2750-2755, 2022 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35377671
4.
Acetylation of the Catalytic Lysine Inhibits Kinase Activity in PI3Kδ.
ACS Chem Biol
; 16(9): 1644-1653, 2021 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34397208
5.
Synthesis and evaluation of novel alpha-amino cyclic boronates as inhibitors of HCV NS3 protease.
Bioorg Med Chem Lett
; 20(12): 3550-6, 2010 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20493689
6.
Evaluation of a crystallographic surrogate for kallikrein 5 in the discovery of novel inhibitors for Netherton syndrome.
Acta Crystallogr F Struct Biol Commun
; 75(Pt 5): 385-391, 2019 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31045568
7.
Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase.
J Med Chem
; 62(10): 5096-5110, 2019 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31013427
8.
4-acyl-1-(4-aminoalkoxyphenyl)-2-ketopiperazines as a novel class of non-brain-penetrant histamine H3 receptor antagonists.
J Med Chem
; 50(26): 6706-17, 2007 Dec 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-18052318