RESUMO
Visual perception by individuals with schizophrenia has not been extensively researched. The focus of this review is the perception of physiological visual illusions by patients with schizophrenia, a differences of perception reported in a small number of studies. Increased or decreased susceptibility of these patients to various illusions seems to be unconnected to the location of origin in the visual apparatus, which also takes place in illusions connected to other modalities. The susceptibility of patients with schizophrenia to haptic illusions has not yet been investigated, although the need for such investigation has been is clear. The emerging picture is that some individuals with schizophrenia are "resistant" to some of the illusions and are able to assess visual phenomena more "rationally", yet certain illusions (ex. Müller-Lyer's) are perceived more intensely. Disturbances in the perception of visual illusions have neither been classified as possible diagnostic indicators of a dangerous mental condition, nor included in the endophenotype of schizophrenia. Although the relevant data are sparse, the ability to replicate the results is limited, and the research model lacks a "gold standard", some preliminary conclusions may be drawn. There are indications that disturbances in visual perception are connected to the extent of disorganization, poor initial social functioning, poor prognosis, and the types of schizophrenia described as neurodevelopmental. Patients with schizophrenia usually fail to perceive those illusions that require volitional controlled attention, and show lack of sensitivity to the contrast between shape and background.
Assuntos
Ilusões Ópticas , Transtornos da Percepção/etiologia , Esquizofrenia/complicações , Transtornos da Visão/etiologia , Percepção Visual , Humanos , Transtornos da Percepção/diagnóstico , Transtornos da Visão/diagnósticoAssuntos
Hipnóticos e Sedativos/farmacocinética , Piridinas/farmacocinética , Transtornos Relacionados ao Uso de Substâncias/sangue , Relação Dose-Resposta a Droga , Humanos , Hipnóticos e Sedativos/administração & dosagem , Inativação Metabólica , Taxa de Depuração Metabólica/fisiologia , Piridinas/efeitos adversos , Convulsões/sangue , Convulsões/induzido quimicamente , Síndrome de Abstinência a Substâncias/sangue , Síndrome de Abstinência a Substâncias/psicologia , Transtornos Relacionados ao Uso de Substâncias/psicologia , ZolpidemRESUMO
Wilson's disease (WD), or hepatolenticular degeneration, is a genetic neurodegenerative disorder of copper metabolism. It is an uncommon medical condition that produces psychiatric symptoms during the early phase in approximately 50% of patients. Reported herein is a case of WD in a young man presenting persistent delusional disorder of organic etiology, which resolved entirely after 4 months of combined pharmacotherapy. The present case demonstrates the importance of considering the occurrence of psychotic symptoms in WD patients given that psychiatric manifestations in WD are known to be uncommon as well as inhomogeneous. It also supports the hypothesis that psychopathologic features in WD have an organic foundation.