Detalhe da pesquisa
1.
A Simple Computational Tool for Accurate, Quantitative Prediction of One-Electron Reduction Potentials of Hypoxia-Activated Tirapazamine Analogues.
J Pharm Pharm Sci
; 23: 231-242, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32574141
2.
Synthesis of [18F]F-γ-T-3, a Redox-Silent γ-Tocotrienol (γ-T-3) Vitamin E Analogue for Image-Based In Vivo Studies of Vitamin E Biodistribution and Dynamics.
Molecules
; 25(23)2020 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33287202
3.
Positron Emission Tomography (PET) and Pharmacokinetics: Classical Blood Sampling Versus Image-Derived Analysis of [18F]FAZA and [18F]FDG in a Murine Tumor Bearing Model.
J Pharm Pharm Sci
; 21(1s): 32s-47s, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29702045
4.
Synthesis and Preliminary Evaluation of an ASGPr-Targeted Polycationic ß-Cyclodextrin Carrier for Nucleosides and Nucleotides.
Pharmaceutics
; 16(3)2024 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38543217
5.
Radiation Dosimetry of Theragnostic Pairs for Isotopes of Iodine in IAZA.
Pharmaceutics
; 14(8)2022 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36015281
6.
Synthesis, radiofluorination, and hypoxia-selective studies of FRAZ: A configurational and positional analogue of the clinical hypoxia marker, [18F]-FAZA.
Bioorg Med Chem
; 18(6): 2255-2264, 2010 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20181485
7.
Initial results of hypoxia imaging using 1-alpha-D: -(5-deoxy-5-[18F]-fluoroarabinofuranosyl)-2-nitroimidazole ( 18F-FAZA).
Eur J Nucl Med Mol Imaging
; 36(10): 1565-73, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19430784
8.
Development of [131I]I-EOE-TPZ and [131I]I-EOE-TPZMO: Novel Tirapazamine (TPZ)-Based Radioiodinated Pharmaceuticals for Application in Theranostic Management of Hypoxia.
Pharmaceuticals (Basel)
; 12(1)2019 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30609671
9.
Synthesis of [18F]FAZA Using Nosyl and Iodo Precursors for Nucleophilic Radiofluorination.
Curr Radiopharm
; 12(1): 49-57, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30338747
10.
Putative electron-affinic radiosensitizers and markers of hypoxic tissue: Synthesis and preliminary in vitro biological characterization of C3-amino-substituted benzotriazine dioxides (BTDOs).
Eur J Med Chem
; 165: 216-224, 2019 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30684798
11.
Stereospecific deuteration of alpha-furanosyl azomycin nucleosides: a model reaction for tritium radiolabeling.
Bioorg Med Chem Lett
; 18(11): 3256-60, 2008 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18479915
12.
Preparation and preliminary evaluation of novel beta-cyclodextrin/IUDR prodrug formulations.
J Pharm Pharm Sci
; 11(2): 32s-43s, 2008 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19203469
13.
Asialoglycoprotein receptor-targeted superparamagnetic iron oxide nanoparticles.
Int J Pharm
; 360(1-2): 197-203, 2008 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-18539417
14.
Targeted delivery of macromolecular drugs: asialoglycoprotein receptor (ASGPR) expression by selected hepatoma cell lines used in antiviral drug development.
Curr Drug Deliv
; 5(4): 299-302, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18855599
15.
Radioiodination of 1-(2-deoxy-beta-D-ribofuranosyl)-2,4-difluoro-5-iodobenzene (dRFIB), a putative thymidine mimic nucleoside for cell proliferation studies.
Appl Radiat Isot
; 66(9): 1221-8, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18662615
16.
Pharmacokinetics and Scintigraphic Imaging of the Hypoxia-Imaging Agent [123I]IAZA in Healthy Adults Following Exercise-Based Cardiac Stress .
Pharmaceutics
; 10(1)2018 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29470434
17.
5-alkynyl analogs of arabinouridine and 2'-deoxyuridine: cytostatic activity against herpes simplex virus and varicella-zoster thymidine kinase gene-transfected cells.
J Med Chem
; 50(12): 2851-7, 2007 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-17518459
18.
Characterization of a cyclodextrinoligonucleotide complex by capillary electrophoresis using laser-induced fluorescence.
J Pharm Pharm Sci
; 10(2): 246-55, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17706183
19.
A novel and efficient synthesis of [2-11C]5-fluorouracil for prognosis of cancer chemotherapy.
J Pharm Pharm Sci
; 10(2): 212-6, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17706179
20.
Synthesis, transportability and hypoxiaselective binding of 1-beta-D-(5-Deoxy-5-fluororibofuranosyl)-2-nitroimidazole (beta-5-FAZR), a configurational isomer of the clinical hypoxia marker, FAZA.
J Pharm Pharm Sci
; 10(2): 237-45, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17706182