Detalhe da pesquisa
1.
Human Memory B Cells Harbor Diverse Cross-Neutralizing Antibodies against BK and JC Polyomaviruses.
Immunity
; 50(3): 668-676.e5, 2019 03 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30824324
2.
The influence of epidural analgesic techniques on obstetrical outcomes.
Arch Gynecol Obstet
; 2024 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38880792
3.
Author Correction: Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.
Nat Chem Biol
; 16(3): 361, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-31942047
4.
Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.
Nat Chem Biol
; 16(1): 15-23, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31819272
5.
Small-molecule factor B inhibitor for the treatment of complement-mediated diseases.
Proc Natl Acad Sci U S A
; 116(16): 7926-7931, 2019 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30926668
6.
A small-molecule inhibitor of C5 complement protein.
Nat Chem Biol
; 15(7): 666-668, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31209353
7.
Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers.
Nature
; 501(7466): 232-6, 2013 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23934108
8.
Structure-based design and synthesis of macrocyclic human rhinovirus 3C protease inhibitors.
Bioorg Med Chem Lett
; 28(5): 906-909, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29433930
9.
Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering.
Proc Natl Acad Sci U S A
; 109(14): 5399-404, 2012 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22421438
10.
Structure based design of novel 6,5 heterobicyclic mitogen-activated protein kinase kinase (MEK) inhibitors leading to the discovery of imidazo[1,5-a] pyrazine G-479.
Bioorg Med Chem Lett
; 24(19): 4714-4723, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25193232
11.
Discovery of the 1,7-diazacarbazole class of inhibitors of checkpoint kinase 1.
Bioorg Med Chem Lett
; 24(24): 5704-5709, 2014 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25453805
12.
Inhibiting alternative pathway complement activation by targeting the factor D exosite.
J Biol Chem
; 287(16): 12886-92, 2012 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22362762
13.
A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis.
J Exp Med
; 204(6): 1319-25, 2007 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-17548523
14.
Cis-amide isosteric replacement in thienobenzoxepin inhibitors of PI3-kinase.
Bioorg Med Chem Lett
; 23(3): 897-901, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23265894
15.
Structure of C3b in complex with CRIg gives insights into regulation of complement activation.
Nature
; 444(7116): 217-20, 2006 Nov 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-17051150
16.
Discovery of Novel Quinoline-Based Proteasome Inhibitors for Human African Trypanosomiasis (HAT).
J Med Chem
; 65(17): 11776-11787, 2022 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35993839
17.
Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding.
EMBO J
; 26(23): 4902-12, 2007 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-17989695
18.
Inhibition of Wnt signaling by Dishevelled PDZ peptides.
Nat Chem Biol
; 5(4): 217-9, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19252499
19.
Structure-based design of thienobenzoxepin inhibitors of PI3-kinase.
Bioorg Med Chem Lett
; 21(13): 4054-8, 2011 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21636270
20.
Improving therapeutic efficacy of a complement receptor by structure-based affinity maturation.
J Biol Chem
; 284(51): 35605-11, 2009 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-19833734