Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Transcription factor EGR2 controls homing and pathogenicity of T_H17 cells in the central nervous system.

Gao, Yuanyuan; Wang, Yan; Chauss, Daniel; Villarino, Alejandro V; Link, Verena M; Nagashima, Hiroyuki; Spinner, Camille A; Koparde, Vishal N; Bouladoux, Nicolas; Abers, Michael S; Break, Timothy J; Chopp, Laura B; Park, Jung-Hyun; Zhu, Jinfang; Wiest, David L; Leonard, Warren J; Lionakis, Michail S; O'Shea, John J; Afzali, Behdad; Belkaid, Yasmine; Lazarevic, Vanja.

Nat Immunol ; 24(8): 1331-1344, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37443284

2.

Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate.

Isoda, Takeshi; Moore, Amanda J; He, Zhaoren; Chandra, Vivek; Aida, Masatoshi; Denholtz, Matthew; Piet van Hamburg, Jan; Fisch, Kathleen M; Chang, Aaron N; Fahl, Shawn P; Wiest, David L; Murre, Cornelis.

Cell ; 171(1): 103-119.e18, 2017 Sep 21.

Artigo em Inglês | MEDLINE | ID: mdl-28938112

3.

Doubling down to make killer T cells.

Kappes, Dietmar; Wiest, David L.

Nat Immunol ; 24(9): 1407-1408, 2023 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-37620604

4.

Tissue-infiltrating alloreactive T cells require Id3 to deflect PD-1-mediated immune suppression during GVHD.

Wang, Ying; He, Shan; Calendo, Gennaro; Bui, Tien; Tian, Yuanyuan; Lee, Che Young; Zhou, Yan; Zhao, Xin; Abraham, Ciril; Mo, Wenbin; Chen, Mimi; Sanders-Braggs, Ruqayyah; Madzo, Jozef; Issa, Jean-Pierre; Hexner, Elizabeth O; Wiest, David L; Reshef, Ran; Xue, Hai-Hui; Zhang, Yi.

Blood ; 143(2): 166-177, 2024 Jan 11.

Artigo em Inglês | MEDLINE | ID: mdl-37871574

5.

Disruption of polyunsaturated fatty acid biosynthesis drives STING-dependent acute myeloid leukemia cell maturation and death.

Kanefsky, Joice; Basse, Mary; Sokei, Judith; di Martino, Orsola; Valin, Liana; Jaspers, Yorrick; Martinez, Esteban; Huhn, Jacklyn; Di Marcantonio, Daniela; Magee, Jeffrey A; Goldman, Aaron R; Tang, Hsin-Yao; Ferraro, Francesca; Kemp, Stephan; Wiest, David L; Sykes, Stephen M.

J Biol Chem ; 300(5): 107214, 2024 Mar 22.

Artigo em Inglês | MEDLINE | ID: mdl-38522521

6.

THEMIS-tery is solved.

Wiest, David L.

Nat Immunol ; 18(4): 368-370, 2017 03 22.

Artigo em Inglês | MEDLINE | ID: mdl-28323266

7.

The ERK2-DBP domain opposes pathogenesis of a mouse JAK2V617F-driven myeloproliferative neoplasm.

Zhang, Yong; Truong, Billy; Fahl, Shawn P; Martinez, Esteban; Cai, Kathy Q; Al-Saleem, Essel D; Gong, Yulan; Liebermann, Dan A; Soboloff, Jonathan; Dunbrack, Roland; Levine, Ross L; Fletcher, Steven; Kappes, Dietmar; Sykes, Stephen M; Shapiro, Paul; Wiest, David L.

Blood ; 140(4): 359-373, 2022 07 28.

Artigo em Inglês | MEDLINE | ID: mdl-35436326

8.

Loss of Ribosomal Protein Paralog Rpl22-like1 Blocks Lymphoid Development without Affecting Protein Synthesis.

Fahl, Shawn P; Sertori, Robert; Zhang, Yong; Contreras, Alejandra V; Harris, Bryan; Wang, Minshi; Perrigoue, Jacqueline; Balachandran, Siddharth; Kennedy, Brian K; Wiest, David L.

J Immunol ; 208(4): 870-880, 2022 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-35046107

9.

Noncanonical mode of ERK action controls alternative αß and Î³Î´ T cell lineage fates.

Lee, Sang-Yun; Coffey, Francis; Fahl, Shawn P; Peri, Suraj; Rhodes, Michele; Cai, Kathy Q; Carleton, Michael; Hedrick, Stephen M; Fehling, Hans Joerg; Zúñiga-Pflücker, Juan Carlos; Kappes, Dietmar J; Wiest, David L.

Immunity ; 41(6): 934-46, 2014 Dec 18.

Artigo em Inglês | MEDLINE | ID: mdl-25526308

10.

Role of a selecting ligand in shaping the murine Î³Î´-TCR repertoire.

Fahl, Shawn P; Coffey, Francis; Kain, Lisa; Zarin, Payam; Dunbrack, Roland L; Teyton, Luc; Zúñiga-Pflücker, Juan Carlos; Kappes, Dietmar J; Wiest, David L.

Proc Natl Acad Sci U S A ; 115(8): 1889-1894, 2018 02 20.

Artigo em Inglês | MEDLINE | ID: mdl-29432160

11.

Id3 Restricts Î³Î´ NKT Cell Expansion by Controlling Egr2 and c-Myc Activity.

Zhang, Baojun; Jiao, Anjun; Dai, Meifang; Wiest, David L; Zhuang, Yuan.

J Immunol ; 201(5): 1452-1459, 2018 09 01.

Artigo em Inglês | MEDLINE | ID: mdl-30012846

12.

Multisystem Anomalies in Severe Combined Immunodeficiency with Mutant BCL11B.

Punwani, Divya; Zhang, Yong; Yu, Jason; Cowan, Morton J; Rana, Sadhna; Kwan, Antonia; Adhikari, Aashish N; Lizama, Carlos O; Mendelsohn, Bryce A; Fahl, Shawn P; Chellappan, Ajithavalli; Srinivasan, Rajgopal; Brenner, Steven E; Wiest, David L; Puck, Jennifer M.

N Engl J Med ; 375(22): 2165-2176, 2016 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-27959755

13.

Disruption of Thrombocyte and T Lymphocyte Development by a Mutation in ARPC1B.

Somech, Raz; Lev, Atar; Lee, Yu Nee; Simon, Amos J; Barel, Ortal; Schiby, Ginette; Avivi, Camila; Barshack, Iris; Rhodes, Michele; Yin, Jiejing; Wang, Minshi; Yang, Yibin; Rhodes, Jennifer; Marcus, Nufar; Garty, Ben-Zion; Stein, Jerry; Amariglio, Ninette; Rechavi, Gideon; Wiest, David L; Zhang, Yong.

J Immunol ; 199(12): 4036-4045, 2017 12 15.

Artigo em Inglês | MEDLINE | ID: mdl-29127144

14.

Integration of T-cell receptor, Notch and cytokine signals programs mouse Î³Î´ T-cell effector differentiation.

Zarin, Payam; In, Tracy Sh; Chen, Edward Ly; Singh, Jastaranpreet; Wong, Gladys W; Mohtashami, Mahmood; Wiest, David L; Anderson, Michele K; Zúñiga-Pflücker, Juan Carlos.

Immunol Cell Biol ; 96(9): 994-1007, 2018 10.

Artigo em Inglês | MEDLINE | ID: mdl-29754419

15.

Marked induction of the helix-loop-helix protein Id3 promotes the gammadelta T cell fate and renders their functional maturation Notch independent.

Lauritsen, Jens Peter Holst; Wong, Gladys W; Lee, Sang-Yun; Lefebvre, Juliette M; Ciofani, Maria; Rhodes, Michele; Kappes, Dietmar J; Zúñiga-Pflücker, Juan Carlos; Wiest, David L.

Immunity ; 31(4): 565-75, 2009 Oct 16.

Artigo em Inglês | MEDLINE | ID: mdl-19833086

16.

Rpl22 Loss Selectively Impairs αß T Cell Development by Dysregulating Endoplasmic Reticulum Stress Signaling.

Solanki, Nehal R; Stadanlick, Jason E; Zhang, Yong; Duc, Ann-Cecile; Lee, Sang-Yun; Lauritsen, Jens Peter Holst; Zhang, Zhiqiang; Wiest, David L.

J Immunol ; 197(6): 2280-9, 2016 09 15.

Artigo em Inglês | MEDLINE | ID: mdl-27489283

17.

Rpl22 Loss Impairs the Development of B Lymphocytes by Activating a p53-Dependent Checkpoint.

Fahl, Shawn P; Harris, Bryan; Coffey, Francis; Wiest, David L.

J Immunol ; 194(1): 200-9, 2015 Jan 01.

Artigo em Inglês | MEDLINE | ID: mdl-25416806

18.

Enforcement of Î³Î´-lineage commitment by the pre-T-cell receptor in precursors with weak Î³Î´-TCR signals.

Zarin, Payam; Wong, Gladys W; Mohtashami, Mahmood; Wiest, David L; Zúñiga-Pflücker, Juan Carlos.

Proc Natl Acad Sci U S A ; 111(15): 5658-63, 2014 Apr 15.

Artigo em Inglês | MEDLINE | ID: mdl-24706811

19.

Appl1 and Appl2 are Expendable for Mouse Development But Are Essential for HGF-Induced Akt Activation and Migration in Mouse Embryonic Fibroblasts.

Tan, Yinfei; Xin, Xiaoban; Coffey, Francis J; Wiest, David L; Dong, Lily Q; Testa, Joseph R.

J Cell Physiol ; 231(5): 1142-50, 2016 May.

Artigo em Inglês | MEDLINE | ID: mdl-26445298

20.

Regulatory Roles of Rpl22 in Hematopoiesis: An Old Dog with New Tricks.

Fahl, Shawn P; Wang, Minshi; Zhang, Yong; Duc, Anne-Cecile E; Wiest, David L.

Crit Rev Immunol ; 35(5): 379-400, 2015.

Artigo em Inglês | MEDLINE | ID: mdl-26853850

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