Detalhe da pesquisa
1.
A step-by-step in crystallo guide to bond cleavage and 1,6-anhydro-sugar product synthesis by a peptidoglycan-degrading lytic transglycosylase.
J Biol Chem
; 293(16): 6000-6010, 2018 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29483188
2.
Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway.
Mol Cell
; 44(3): 451-61, 2011 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22055190
3.
Visualization of a substrate-induced productive conformation of the catalytic triad of the Neisseria meningitidis peptidoglycan O-acetylesterase reveals mechanistic conservation in SGNH esterase family members.
Acta Crystallogr D Biol Crystallogr
; 70(Pt 10): 2631-9, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25286847
4.
De-O-acetylation of peptidoglycan regulates glycan chain extension and affects in vivo survival of Neisseria meningitidis.
Mol Microbiol
; 87(5): 1100-12, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23373517
5.
Acetylation regulates the oligomerization state and activity of RNase J, the Helicobacter pylori major ribonuclease.
Nat Commun
; 14(1): 8072, 2023 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38057323
6.
The mechanistic landscape of Lytic transglycosylase as targets for antibacterial therapy.
Curr Opin Struct Biol
; 77: 102480, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36323133
7.
Structural basis for the sugar nucleotide and acyl-chain selectivity of Leptospira interrogans LpxA.
Biochemistry
; 48(26): 6191-201, 2009 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-19456129
8.
Structure guided design of an antibacterial peptide that targets UDP-N-acetylglucosamine acyltransferase.
Sci Rep
; 9(1): 3947, 2019 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30850651
9.
The cryo-electron microscopy supramolecular structure of the bacterial stressosome unveils its mechanism of activation.
Nat Commun
; 10(1): 3005, 2019 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31285450
10.
Author Correction: N-terminomics identifies Prli42 as a membrane miniprotein conserved in Firmicutes and critical for stressosome activation in Listeria monocytogenes.
Nat Microbiol
; 3(8): 962, 2018 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-29941881
11.
Bulgecin A: The Key to a Broad-Spectrum Inhibitor That Targets Lytic Transglycosylases.
Antibiotics (Basel)
; 6(1)2017 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28241458
12.
N-terminomics identifies Prli42 as a membrane miniprotein conserved in Firmicutes and critical for stressosome activation in Listeria monocytogenes.
Nat Microbiol
; 2: 17005, 2017 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28191904
13.
The dynamics of peptidoglycan structure and function: conference report on the 3rd Great Wall Symposium.
Res Microbiol
; 165(1): 60-7, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24239960
14.
Structural basis for the acyl chain selectivity and mechanism of UDP-N-acetylglucosamine acyltransferase.
Proc Natl Acad Sci U S A
; 104(34): 13543-50, 2007 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-17698807
15.
Structure of UDP-N-acetylglucosamine acyltransferase with a bound antibacterial pentadecapeptide.
Proc Natl Acad Sci U S A
; 103(29): 10877-82, 2006 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-16835299
16.
Enzymatic synthesis of lipid A molecules with four amide-linked acyl chains. LpxA acyltransferases selective for an analog of UDP-N-acetylglucosamine in which an amine replaces the 3"-hydroxyl group.
J Biol Chem
; 279(24): 25411-9, 2004 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-15044493