Detalhe da pesquisa
1.
Chromosome 10q26-driven age-related macular degeneration is associated with reduced levels of HTRA1 in human retinal pigment epithelium.
Proc Natl Acad Sci U S A
; 118(30)2021 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34301870
2.
Protective chromosome 1q32 haplotypes mitigate risk for age-related macular degeneration associated with the CFH-CFHR5 and ARMS2/HTRA1 loci.
Hum Genomics
; 15(1): 60, 2021 09 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34563268
3.
Levels of the HtrA1 Protein in Serum and Vitreous Humor Are Independent of Genetic Risk for Age-Related Macular Degeneration at the 10q26 Locus.
Invest Ophthalmol Vis Sci
; 65(4): 34, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38648039
4.
Lead optimization of purine based orally bioavailable Mps1 (TTK) inhibitors.
Bioorg Med Chem Lett
; 22(13): 4377-85, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22632936
5.
Oxindole derivatives as inhibitors of TAK1 kinase.
Bioorg Med Chem Lett
; 21(6): 1724-7, 2011 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21316225
6.
Characterization of the cellular and antitumor effects of MPI-0479605, a small-molecule inhibitor of the mitotic kinase Mps1.
Mol Cancer Ther
; 10(12): 2267-75, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21980130
7.
Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2.
Mol Cell
; 9(5): 1045-54, 2002 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12049740