Detalhe da pesquisa
1.
Dimethyl fumarate and the oleanane triterpenoids, CDDO-imidazolide and CDDO-methyl ester, both activate the Nrf2 pathway but have opposite effects in the A/J model of lung carcinogenesis.
Carcinogenesis
; 36(7): 769-81, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25939751
2.
Novel synthetic pyridyl analogues of CDDO-Imidazolide are useful new tools in cancer prevention.
Pharmacol Res
; 100: 135-47, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26238177
3.
The combination of the histone deacetylase inhibitor vorinostat and synthetic triterpenoids reduces tumorigenesis in mouse models of cancer.
Carcinogenesis
; 34(1): 199-210, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23042302
4.
Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice.
Carcinogenesis
; 30(6): 1024-31, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19386581
5.
Prevention and treatment of experimental estrogen receptor-negative mammary carcinogenesis by the synthetic triterpenoid CDDO-methyl Ester and the rexinoid LG100268.
Clin Cancer Res
; 14(14): 4556-63, 2008 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18628471
6.
The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice.
Cancer Res
; 67(6): 2414-9, 2007 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17363558
7.
The rexinoid LG100268 and the synthetic triterpenoid CDDO-methyl amide are more potent than erlotinib for prevention of mouse lung carcinogenesis.
Mol Cancer Ther
; 7(5): 1251-7, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18483313
8.
A new rexinoid, NRX194204, prevents carcinogenesis in both the lung and mammary gland.
Clin Cancer Res
; 13(20): 6237-43, 2007 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17947492
9.
Novel semisynthetic analogues of betulinic acid with diverse cytoprotective, antiproliferative, and proapoptotic activities.
Mol Cancer Ther
; 6(7): 2113-9, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17620440
10.
The synthetic triterpenoid CDDO-Imidazolide suppresses STAT phosphorylation and induces apoptosis in myeloma and lung cancer cells.
Clin Cancer Res
; 12(14 Pt 1): 4288-93, 2006 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16857804
11.
The combination of the rexinoid, LG100268, and a selective estrogen receptor modulator, either arzoxifene or acolbifene, synergizes in the prevention and treatment of mammary tumors in an estrogen receptor-negative model of breast cancer.
Clin Cancer Res
; 12(19): 5902-9, 2006 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17020999
12.
The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling.
Cancer Res
; 65(11): 4789-98, 2005 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15930299
13.
Bromodomain inhibitors, JQ1 and I-BET 762, as potential therapies for pancreatic cancer.
Cancer Lett
; 394: 76-87, 2017 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28254412
14.
The selective estrogen receptor modulator arzoxifene and the rexinoid LG100268 cooperate to promote transforming growth factor beta-dependent apoptosis in breast cancer.
Cancer Res
; 64(10): 3566-71, 2004 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15150113
15.
Synthetic triterpenoids enhance transforming growth factor beta/Smad signaling.
Cancer Res
; 63(6): 1371-6, 2003 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12649201
16.
The Rexinoids LG100268 and LG101506 Inhibit Inflammation and Suppress Lung Carcinogenesis in A/J Mice.
Cancer Prev Res (Phila)
; 9(1): 105-14, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26554632
17.
The novel synthetic triterpenoid, CDDO-imidazolide, inhibits inflammatory response and tumor growth in vivo.
Clin Cancer Res
; 9(7): 2798-806, 2003 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12855660
18.
Prevention and treatment of experimental breast cancer with the combination of a new selective estrogen receptor modulator, arzoxifene, and a new rexinoid, LG 100268.
Clin Cancer Res
; 8(10): 3270-5, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12374698
19.
Receptor tyrosine kinase ERBB4 mediates acquired resistance to ERBB2 inhibitors in breast cancer cells.
Cell Cycle
; 14(4): 648-55, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25590338
20.
Design, synthesis, and biological evaluation of biotin conjugates of 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid for the isolation of the protein targets.
J Med Chem
; 47(20): 4923-32, 2004 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-15369396