Detalhe da pesquisa
1.
Mechanisms of hepatotoxicity associated with the monocyclic ß-lactam antibiotic BAL30072.
Arch Toxicol
; 91(11): 3647-3662, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28536862
2.
Prediction of Safety Margin and Optimization of Dosing Protocol for a Novel Antibiotic using Quantitative Systems Pharmacology Modeling.
Clin Transl Sci
; 11(5): 498-505, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29877622
3.
Proteolytic processing by matrix metalloproteinases and phosphorylation by protein kinase CK2 of fetuin-A, the major globulin of fetal calf serum.
Biochimie
; 89(3): 410-8, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17110014
4.
Investigation of low-abundant in vitro metabolites of stable isotope-labelled BAL4815 by accurate mass capillary-LC-ESI-qTof-MS and MS/MS.
J Mass Spectrom
; 41(7): 903-10, 2006 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-16810647
5.
Experiments for a systematic comparison between stable-isotope-(deuterium) labeling and radio-((14)C) labeling for the elucidation of the in vitro metabolic pattern of pharmaceutical drugs.
J Pharm Biomed Anal
; 85: 138-44, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23933567
6.
Sulfur as the key element for quantitative protein analysis by capillary liquid chromatography coupled to element mass spectrometry.
Angew Chem Int Ed Engl
; 42(29): 3425-7, 2003 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-12888976
7.
Investigation of the species-dependent in vitro metabolism of BAL30630 by stable isotope labeling and isotope exchange experiments analyzed by capillary liquid chromatography coupled to mass spectrometry.
J Chromatogr A
; 1216(18): 3946-53, 2009 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19327777
8.
Elucidation of the in vitro metabolic profile of stable isotope labeled BAL19403 by accurate mass capillary liquid chromatography/quadrupole time-of-flight mass spectrometry and isotope exchange.
Rapid Commun Mass Spectrom
; 21(7): 1093-9, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17318924
9.
Analysis of CheA histidine phosphorylation and its influence on protein stability by high-resolution element and electrospray mass spectrometry.
Anal Chem
; 77(7): 1957-62, 2005 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15801724
10.
Plk1 docking to GRASP65 phosphorylated by Cdk1 suggests a mechanism for Golgi checkpoint signalling.
EMBO J
; 24(4): 753-65, 2005 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-15678101
11.
Spotting and quantification of phosphoproteins purified by gel electrophoresis and laser ablation-element mass spectrometry with phosphorus-31 detection.
Electrophoresis
; 24(7-8): 1276-80, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12707922
12.
Stable isotope phospho-profiling of fibrinogen and fetuin subunits by element mass spectrometry coupled to capillary liquid chromatography.
Anal Biochem
; 317(1): 26-33, 2003 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12729597
13.
Cell cycle-regulated phosphorylation of the Xenopus polo-like kinase Plx1.
J Biol Chem
; 277(28): 25247-56, 2002 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-11994303
14.
Identification of phosphorylation sites in the polo-like kinases Plx1 and Plk1 by a novel strategy based on element and electrospray high resolution mass spectrometry.
Proteomics
; 2(11): 1516-23, 2002 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-12442251