Detalhe da pesquisa
1.
Identification of New Substrates and Inhibitors of Human CYP2A7.
Molecules
; 29(10)2024 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38792050
2.
Expected and Unexpected Products from the Biochemical Oxidation of Bacterial Alkylquinolones with CYP4F11.
J Nat Prod
; 86(11): 2502-2513, 2023 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37939299
3.
Deciphering the biotransformation mechanism of dialkylresorcinols by CYP4F11.
Bioorg Chem
; 131: 106330, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36565673
4.
Structural determinants of sphingosine-1-phosphate receptor selectivity.
Arch Pharm (Weinheim)
; 356(12): e2300387, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37806764
5.
Solving an Old Puzzle: Elucidation and Evaluation of the Binding Mode of Salvinorin A at the Kappa Opioid Receptor.
Molecules
; 28(2)2023 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36677775
6.
Development of an HPLC-MS/MS Method for Chiral Separation and Quantitation of (R)- and (S)-Salbutamol and Their Sulfoconjugated Metabolites in Urine to Investigate Stereoselective Sulfonation.
Molecules
; 28(20)2023 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37894685
7.
A Combined Bayesian and Similarity-Based Approach for Predicting E. coli Biofilm Inhibition by Phenolic Natural Compounds.
J Nat Prod
; 85(10): 2255-2265, 2022 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36107719
8.
Experimental and Computational Studies on the Biotransformation of Pseudopyronines with Human Cytochrome P450 CYP4F2.
J Nat Prod
; 85(11): 2603-2609, 2022 11 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36327116
9.
Metabolism of the antipsychotic drug olanzapine by CYP3A43.
Xenobiotica
; 52(4): 413-425, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35582917
10.
Complete Reaction Phenotyping of Propranolol and 4-Hydroxypropranolol with the 19 Enzymes of the Human UGT1 and UGT2 Families.
Int J Mol Sci
; 23(13)2022 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35806479
11.
Mechanistic Characterization of the Pharmacological Profile of HS-731, a Peripherally Acting Opioid Analgesic, at the µ-, δ-, κ-Opioid and Nociceptin Receptors.
Molecules
; 27(3)2022 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35164182
12.
A convenient test system for the identification of CYP4V2 inhibitors.
Mol Vis
; 27: 601-607, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34880593
13.
Dynophore-Based Approach in Virtual Screening: A Case of Human DNA Topoisomerase IIα.
Int J Mol Sci
; 22(24)2021 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34948269
14.
Antinociceptive Efficacy of the µ-Opioid/Nociceptin Peptide-Based Hybrid KGNOP1 in Inflammatory Pain without Rewarding Effects in Mice: An Experimental Assessment and Molecular Docking.
Molecules
; 26(11)2021 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34071603
15.
In Search for Multi-Target Ligands as Potential Agents for Diabetes Mellitus and Its Complications-A Structure-Activity Relationship Study on Inhibitors of Aldose Reductase and Protein Tyrosine Phosphatase 1B.
Molecules
; 26(2)2021 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33435264
16.
Chemical Evolution of Antivirals Against Enterovirus D68 through Protein-Templated Knoevenagel Reactions.
Angew Chem Int Ed Engl
; 60(24): 13294-13301, 2021 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33749121
17.
N-methyl-D-aspartate receptor dysfunction by unmutated human antibodies against the NR1 subunit.
Ann Neurol
; 85(5): 771-776, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30843274
18.
Design and synthesis of 3,5-substituted 1,2,4-oxadiazoles as catalytic inhibitors of human DNA topoisomerase IIα.
Bioorg Chem
; 99: 103828, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32315896
19.
Biased Ligands Differentially Shape the Conformation of the Extracellular Loop Region in 5-HT2B Receptors.
Int J Mol Sci
; 21(24)2020 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33419260
20.
Mechanistic Understanding of Peptide Analogues, DALDA, [Dmt1]DALDA, and KGOP01, Binding to the mu Opioid Receptor.
Molecules
; 25(9)2020 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32365707