Detalhe da pesquisa
1.
Towards a future regulatory framework for chemicals in the European Union - Chemicals 2.0.
Regul Toxicol Pharmacol
; 142: 105431, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37315707
2.
A scheme to evaluate structural alerts to predict toxicity - Assessing confidence by characterising uncertainties.
Regul Toxicol Pharmacol
; 135: 105249, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36041585
3.
Use of New Approach Methodologies (NAMs) in regulatory decisions for chemical safety: Report from an EPAA Deep Dive Workshop.
Regul Toxicol Pharmacol
; 135: 105261, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36103951
4.
Quantitative adverse outcome pathway (qAOP) models for toxicity prediction.
Arch Toxicol
; 94(5): 1497-1510, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32424443
5.
Regulatory assessment and risk management of chemical mixtures: challenges and ways forward.
Crit Rev Toxicol
; 49(2): 174-189, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30931677
6.
Development and analysis of an adverse outcome pathway network for human neurotoxicity.
Arch Toxicol
; 93(10): 2759-2772, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31444508
7.
Can currently available non-animal methods detect pre and pro-haptens relevant for skin sensitization?
Regul Toxicol Pharmacol
; 82: 147-155, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27569201
8.
Integrated Approaches to Testing and Assessment.
Adv Exp Med Biol
; 856: 317-342, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27671729
9.
Validation of Computational Methods.
Adv Exp Med Biol
; 856: 165-187, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27671722
10.
Exploring waiving opportunities for mammalian acute systemic toxicity tests.
Altern Lab Anim
; 44(3): 271-9, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-27494626
11.
Evaluation of non-animal methods for assessing skin sensitisation hazard: A Bayesian Value-of-Information analysis.
Altern Lab Anim
; 44(3): 255-69, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-27494625
12.
A tutorial for analysing the cost-effectiveness of alternative methods for assessing chemical toxicity: the case of acute oral toxicity prediction.
Altern Lab Anim
; 42(2): 115-27, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24901905
13.
In Silico Models for Predicting Acute Systemic Toxicity.
Methods Mol Biol
; 2425: 259-289, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35188637
14.
A matter of trust: Learning lessons about causality will make qAOPs credible.
Comput Toxicol
; 21: 100205, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35224319
15.
Probabilistic modelling of developmental neurotoxicity based on a simplified adverse outcome pathway network.
Comput Toxicol
; 21: 100206, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35211661
16.
The role of validation in establishing the scientific credibility of predictive toxicology approaches intended for regulatory application.
Comput Toxicol
; 17: 100144, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33681540
17.
Computational modelling for the sustainable management of chemicals.
Comput Toxicol
; 14: 100122, 2020 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-32421066
18.
Modeling the structure-property relationships of nanoneedles: A journey toward nanomedicine.
J Comput Chem
; 30(2): 275-84, 2009 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-18615420
19.
Unlocking the potential of in silico chemical safety assessment - A report on a cross-sector symposium on current opportunities and future challenges.
Comput Toxicol
; 10: 38-43, 2019 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-31218266
20.
Membrane transporter data to support kinetically-informed chemical risk assessment using non-animal methods: Scientific and regulatory perspectives.
Environ Int
; 126: 659-671, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30856453