Detalhe da pesquisa
1.
Clustered telomeres in phase-separated nuclear condensates engage mitotic DNA synthesis through BLM and RAD52.
Genes Dev
; 33(13-14): 814-827, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31171703
2.
Telomeres and telomerase: three decades of progress.
Nat Rev Genet
; 20(5): 299-309, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30760854
3.
Telomere extension occurs at most chromosome ends and is uncoupled from fill-in in human cancer cells.
Cell
; 138(3): 463-75, 2009 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-19665970
4.
Telomere position effect: regulation of gene expression with progressive telomere shortening over long distances.
Genes Dev
; 28(22): 2464-76, 2014 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25403178
5.
Catalysis-dependent inactivation of human telomerase and its reactivation by intracellular telomerase-activating factors (iTAFs).
J Biol Chem
; 294(30): 11579-11596, 2019 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31186347
6.
2D gel electrophoresis reveals dynamics of t-loop formation during the cell cycle and t-loop in maintenance regulated by heterochromatin state.
J Biol Chem
; 294(16): 6645-6656, 2019 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30819801
7.
Early and late steps in telomere overhang processing in normal human cells: the position of the final RNA primer drives telomere shortening.
Genes Dev
; 26(11): 1167-78, 2012 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22661228
8.
Regulation of the Human Telomerase Gene TERT by Telomere Position Effect-Over Long Distances (TPE-OLD): Implications for Aging and Cancer.
PLoS Biol
; 14(12): e2000016, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27977688
9.
Processive and distributive extension of human telomeres by telomerase under homeostatic and nonequilibrium conditions.
Mol Cell
; 42(3): 297-307, 2011 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-21549308
10.
Alternative lengthening of telomeres can be maintained by preferential elongation of lagging strands.
Nucleic Acids Res
; 45(5): 2615-2628, 2017 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28082393
11.
SORBS2 transcription is activated by telomere position effect-over long distance upon telomere shortening in muscle cells from patients with facioscapulohumeral dystrophy.
Genome Res
; 25(12): 1781-90, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26359233
12.
Alternative splicing regulation of telomerase: a new paradigm?
Trends Genet
; 30(10): 430-8, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25172021
13.
Impaired telomere maintenance in Alazami syndrome patients with LARP7 deficiency.
BMC Genomics
; 17(Suppl 9): 749, 2016 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27766953
14.
Human CST promotes telomere duplex replication and general replication restart after fork stalling.
EMBO J
; 31(17): 3537-49, 2012 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-22863775
15.
Quantitative telomerase enzyme activity determination using droplet digital PCR with single cell resolution.
Nucleic Acids Res
; 42(13): e104, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24861623
16.
Exome Sequencing of Normal and Isogenic Transformed Human Colonic Epithelial Cells (HCECs) Reveals Novel Genes Potentially Involved in the Early Stages of Colorectal Tumorigenesis.
BMC Genomics
; 16 Suppl 1: S8, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25923178
17.
Large-scale population analysis challenges the current criteria for the molecular diagnosis of fascioscapulohumeral muscular dystrophy.
Am J Hum Genet
; 90(4): 628-35, 2012 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22482803
18.
Tissue culture as a hostile environment: identifying conditions for breast cancer progression studies.
Cancer Cell
; 12(2): 100-1, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17692800
19.
Targeting of Nrf2 induces DNA damage signaling and protects colonic epithelial cells from ionizing radiation.
Proc Natl Acad Sci U S A
; 109(43): E2949-55, 2012 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23045680
20.
Branching morphogenesis of immortalized human bronchial epithelial cells in three-dimensional culture.
Differentiation
; 87(3-4): 119-26, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24830354