Detalhe da pesquisa
1.
Semipinacol Rearrangement of Iododifluorohomoallyl Alcohols and Its Application in the Allylic C-H Esterification Reactions.
J Org Chem
; 89(5): 3111-3122, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38343173
2.
Direct Oxidative Cyclization of 3-Arylpropionic Acids to 3,4-Dihydrocoumarins: Reinvestigation of the Reaction Mechanism.
J Org Chem
; 89(8): 5287-5297, 2024 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38568740
3.
Biocatalytic asymmetric reduction of fluoroalkyl ketones to access enantiopure fluoroalkyl secondary alcohols.
Org Biomol Chem
; 21(17): 3623-3627, 2023 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37066489
4.
Copper-catalyzed radical-mediated intermolecular cyanomonofluoroalkylation of alkenes and alkynes.
Org Biomol Chem
; 21(16): 3447-3452, 2023 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37039316
5.
Ethoxy-erianin phosphate and afatinib synergistically inhibit liver tumor growth and angiogenesis via regulating VEGF and EGFR signaling pathways.
Toxicol Appl Pharmacol
; 438: 115911, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35143806
6.
Enantioselective Copper-Catalyzed Intermolecular Cyanobenzoyldifluoromethylation of Alkenes: Access to Chiral ß-Difluoroacyl Nitriles.
J Org Chem
; 87(6): 4107-4111, 2022 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35209716
7.
Design, Synthesis, Biological Evaluation, and Molecular Modeling of 2-Difluoromethylbenzimidazole Derivatives as Potential PI3Kα Inhibitors.
Molecules
; 27(2)2022 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35056702
8.
A high-throughput and simultaneous determination of combretastatin A-4 phosphate and its metabolites in human plasma using HPLC-MS/MS: Application to a clinical pharmacokinetic study.
Biomed Chromatogr
; 35(11): e5204, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34165810
9.
Copper-mediated cascade radical cyclization of olefins with naphthalenyl iododifluoromethyl ketones.
Org Biomol Chem
; 17(26): 6426-6431, 2019 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31206117
10.
Discovery of (E)-1-amino-4-phenylbut-3-en-2-ol derivatives as novel neuraminidase inhibitors.
Bioorg Med Chem Lett
; 28(11): 2003-2007, 2018 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29748050
11.
Discovery of potent and selective urea-based ROCK inhibitors: Exploring the inhibitor's potency and ROCK2/PKA selectivity by 3D-QSAR, molecular docking and molecular dynamics simulations.
Bioorg Med Chem
; 23(10): 2505-17, 2015 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25882521
12.
Efficient and facile synthesis of novel stable monodeuterium labeled ractopamine.
J Labelled Comp Radiopharm
; 58(13-14): 479-82, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26526706
13.
Molecular modeling studies of atorvastatin analogues as HMGR inhibitors using 3D-QSAR, molecular docking and molecular dynamics simulations.
Bioorg Med Chem Lett
; 24(16): 3869-76, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25022881
14.
2-carbomethoxy-3-hydroxyquinoxaline-di-N-oxide as a novel ligand for the copper-catalyzed coupling reaction of phenols and aryl halides.
Org Biomol Chem
; 11(9): 1502-10, 2013 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23338157
15.
Visible-Light-Induced Copper-Catalyzed Intermolecular Three-Component Difluoroalkyl Thiocyanidation of Alkenes.
Org Lett
; 25(26): 4835-4839, 2023 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37358365
16.
Synthesis of quinoxaline 1,4-di-N-oxide analogues and crystal structure of 2-carbomethoxy-3-hydroxyquinoxaline-di-N-oxide.
Molecules
; 16(8): 6894-901, 2011 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21841728
17.
Design, synthesis and biological evaluation of combretastatin A-4 sulfamate derivatives as potential anti-cancer agents.
RSC Med Chem
; 12(8): 1374-1380, 2021 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34458740
18.
Ecust004 Suppresses Breast Cancer Cell Growth, Invasion, and Migration via EMT Regulation.
Drug Des Devel Ther
; 15: 3451-3461, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34408399
19.
Nickel-Catalyzed Coupling Reaction of α-Bromo-α-fluoroketones with Arylboronic Acids toward the Synthesis of α-Fluoroketones.
Org Lett
; 21(17): 6844-6849, 2019 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31411478
20.
Highly enantioselective construction of 3-hydroxy oxindoles through a decarboxylative aldol addition of trifluoromethyl α-fluorinated gem-diols to N-benzyl isatins.
Angew Chem Int Ed Engl
; 52(21): 5566-70, 2013 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-23589222